lecture 15 true and false quiz- immunology

Th17 cells primarily target intracellular pathogens and activate phagocytes.

Th1 cells are mainly responsible for defending against extracellular pathogens.

Th17 cells produce interleukin-17 (IL-17) and IL-21, but not IL-22.

Neutrophils play a crucial role in eliminating intracellular pathogens according to Th17 cells.

Th17 cells contribute to the maintenance of mucosal barrier integrity.

Th17 cells are important for defense against intracellular bacteria and viruses.

Excessive Th17 responses can lead to the pathogenesis of psoriasis and rheumatoid arthritis.

Th1 cells enhance the barrier function in the body to prevent infections.

Th2 cells are implicated in autoimmune diseases and inflammation.

Understanding the roles of Th1, Th2, and Th17 cells is not important for developing targeted therapeutic interventions for immune-related disorders.

Th1 cells are crucial for defense against extracellular pathogens like bacteria and fungi.

Excessive Th1 responses can lead to tissue damage and contribute to the pathogenesis of autoimmune diseases.

Th2 cells are essential for defense against bacterial infections.

Th2 cells are implicated in allergic diseases like asthma and allergic rhinitis.

Th17 cells primarily target eosinophils.

Activated macrophages downregulate the expression of co-stimulatory molecules such as CD80 and CD86.

Uncontrolled activation of macrophages can lead to enhanced tissue repair and regeneration.

Th1 cells play a central role in activating macrophages through IL-4 signaling.

Th17 cells are involved in promoting inflammation and host defense against extracellular pathogens.

The interaction between Th1 cells and macrophages plays a minor role in the immune response against intracellular microbes.

CD40L expressed on Th2 cells interacts with CD40 receptors on macrophages.

IFN-γ receptors on macrophages are activated by interferon-gamma produced by Th2 cells.

Th1 cells primarily regulate humoral immunity against pathogens like viruses and bacteria.

Th1 cells recognize antigens presented by MHC-II molecules on the surface of infected macrophages.

Th17 cells are involved in maintaining mucosal barrier integrity.

CD4+ helper T cells are also known as T helper cells.

Activated macrophages increase their capacity to kill bacteria through the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS).

Th2 cells are primarily responsible for activating eosinophils.

Th17 cells secrete pro-inflammatory cytokines such as TNF-α, IL-1, and IL-6.

Th1 cells activate macrophages to destroy intracellular microbes.

Th2 cells are primarily induced in response to viral infections and bacterial exposure.

IL-4 is the defining cytokine produced by Th2 cells, essential for initiating and driving the Th2 immune response.

Antigen-presenting cells (APCs) like dendritic cells present helminth antigens or allergens to naive CD8+ T cells.

Naive CD4+ T cells differentiate into Th2 cells under the influence of IL-17.

Proliferation and differentiation of Th2 cells involve the activation of specific transcription factors and epigenetic changes.

Th2 cells are primarily involved in orchestrating immune responses against bacterial infections.

Th1 cells activate macrophages to destroy extracellular microbes.

The main function of Th17 cells is to target extracellular pathogens and activate phagocytes.

Understanding the roles of Th1, Th2, and Th17 cells is crucial for developing targeted therapeutic interventions for immune-related disorders.

Neutrophils play a crucial role in eliminating intracellular pathogens according to Th2 cells.