lecture 15 true and false quiz- immunology
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Questions and Answers

Th17 cells primarily target intracellular pathogens and activate phagocytes.

False

Th1 cells are mainly responsible for defending against extracellular pathogens.

False

Th17 cells produce interleukin-17 (IL-17) and IL-21, but not IL-22.

False

Neutrophils play a crucial role in eliminating intracellular pathogens according to Th17 cells.

<p>False</p> Signup and view all the answers

Th17 cells contribute to the maintenance of mucosal barrier integrity.

<p>True</p> Signup and view all the answers

Th17 cells are important for defense against intracellular bacteria and viruses.

<p>False</p> Signup and view all the answers

Excessive Th17 responses can lead to the pathogenesis of psoriasis and rheumatoid arthritis.

<p>True</p> Signup and view all the answers

Th1 cells enhance the barrier function in the body to prevent infections.

<p>False</p> Signup and view all the answers

Th2 cells are implicated in autoimmune diseases and inflammation.

<p>False</p> Signup and view all the answers

Understanding the roles of Th1, Th2, and Th17 cells is not important for developing targeted therapeutic interventions for immune-related disorders.

<p>False</p> Signup and view all the answers

Th1 cells are crucial for defense against extracellular pathogens like bacteria and fungi.

<p>False</p> Signup and view all the answers

Excessive Th1 responses can lead to tissue damage and contribute to the pathogenesis of autoimmune diseases.

<p>True</p> Signup and view all the answers

Th2 cells are essential for defense against bacterial infections.

<p>False</p> Signup and view all the answers

Th2 cells are implicated in allergic diseases like asthma and allergic rhinitis.

<p>True</p> Signup and view all the answers

Th17 cells primarily target eosinophils.

<p>False</p> Signup and view all the answers

Activated macrophages downregulate the expression of co-stimulatory molecules such as CD80 and CD86.

<p>False</p> Signup and view all the answers

Uncontrolled activation of macrophages can lead to enhanced tissue repair and regeneration.

<p>False</p> Signup and view all the answers

Th1 cells play a central role in activating macrophages through IL-4 signaling.

<p>False</p> Signup and view all the answers

Th17 cells are involved in promoting inflammation and host defense against extracellular pathogens.

<p>True</p> Signup and view all the answers

The interaction between Th1 cells and macrophages plays a minor role in the immune response against intracellular microbes.

<p>False</p> Signup and view all the answers

CD40L expressed on Th2 cells interacts with CD40 receptors on macrophages.

<p>False</p> Signup and view all the answers

IFN-γ receptors on macrophages are activated by interferon-gamma produced by Th2 cells.

<p>False</p> Signup and view all the answers

Th1 cells primarily regulate humoral immunity against pathogens like viruses and bacteria.

<p>False</p> Signup and view all the answers

Th1 cells recognize antigens presented by MHC-II molecules on the surface of infected macrophages.

<p>True</p> Signup and view all the answers

Th17 cells are involved in maintaining mucosal barrier integrity.

<p>False</p> Signup and view all the answers

CD4+ helper T cells are also known as T helper cells.

<p>True</p> Signup and view all the answers

Activated macrophages increase their capacity to kill bacteria through the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS).

<p>True</p> Signup and view all the answers

Th2 cells are primarily responsible for activating eosinophils.

<p>True</p> Signup and view all the answers

Th17 cells secrete pro-inflammatory cytokines such as TNF-α, IL-1, and IL-6.

<p>False</p> Signup and view all the answers

Th1 cells activate macrophages to destroy intracellular microbes.

<p>True</p> Signup and view all the answers

Th2 cells are primarily induced in response to viral infections and bacterial exposure.

<p>False</p> Signup and view all the answers

IL-4 is the defining cytokine produced by Th2 cells, essential for initiating and driving the Th2 immune response.

<p>True</p> Signup and view all the answers

Antigen-presenting cells (APCs) like dendritic cells present helminth antigens or allergens to naive CD8+ T cells.

<p>False</p> Signup and view all the answers

Naive CD4+ T cells differentiate into Th2 cells under the influence of IL-17.

<p>False</p> Signup and view all the answers

Proliferation and differentiation of Th2 cells involve the activation of specific transcription factors and epigenetic changes.

<p>True</p> Signup and view all the answers

Th2 cells are primarily involved in orchestrating immune responses against bacterial infections.

<p>False</p> Signup and view all the answers

Th1 cells activate macrophages to destroy extracellular microbes.

<p>False</p> Signup and view all the answers

The main function of Th17 cells is to target extracellular pathogens and activate phagocytes.

<p>False</p> Signup and view all the answers

Understanding the roles of Th1, Th2, and Th17 cells is crucial for developing targeted therapeutic interventions for immune-related disorders.

<p>True</p> Signup and view all the answers

Neutrophils play a crucial role in eliminating intracellular pathogens according to Th2 cells.

<p>False</p> Signup and view all the answers

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