TH1, TH2, TH17, and Cytotoxic T Cells Quiz
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Questions and Answers

What is the primary role of cytotoxic T cells (CD8+ T cells)?

  • To promote local innate defense against pathogens.
  • To directly attack and kill other cells that display the antigen they have been sensitized to. (correct)
  • To coordinate the adaptive immune response by secreting cytokines.
  • To undergo isotype switching and differentiate into plasma cells.

Which of the following best describes the function of B cell memory?

  • B cell memory is necessary for isotype switching to occur.
  • B cell memory allows for a rapid and robust antibody response upon re-exposure to the same antigen. (correct)
  • B cell memory is responsible for the non-specific release of antibodies.
  • B cell memory enables the production of large amounts of antibodies as plasma cells.

What is the primary role of T helper (TH) cells in the adaptive immune response?

  • TH cells coordinate the adaptive immune response by secreting cytokines. (correct)
  • TH cells undergo isotype switching and differentiate into plasma cells.
  • TH cells directly attack and kill cells displaying the antigen they recognize.
  • TH cells promote local innate defense against pathogens.

What is the difference between active and passive immunity?

<p>Active immunity involves the production of antibodies or T cells after exposure to an antigen, while passive immunity involves the transfer of preformed antibodies or T cells from a donor. (C)</p> Signup and view all the answers

Which of the following best describes the relationship between T helper (TH) cells and B cells?

<p>TH cells coordinate the activation and differentiation of B cells through co-stimulation and cytokine signaling. (A)</p> Signup and view all the answers

How do cytokines characteristic of TH1 and TH2 cells differ in their effects on the immune response?

<p>TH1 cytokines indirectly promote inflammation, while TH2 cytokines directly attack and kill other cells. (C)</p> Signup and view all the answers

Which type of hypersensitivity reaction involves the production of IgG antibodies that bind to modified cells and make them susceptible to destruction?

<p>Type II (D)</p> Signup and view all the answers

Which type of hypersensitivity reaction is mediated by the deposition of immune complexes and the activation of inflammatory cells and the complement cascade?

<p>Type III (B)</p> Signup and view all the answers

Which type of T helper cells produce cytokines that recruit and activate eosinophils, leading to their degranulation and tissue injury?

<p>TH2 cells (A)</p> Signup and view all the answers

Which of the following is NOT a function of TH1 cells?

<p>Inducing macrophage differentiation in bone marrow (A)</p> Signup and view all the answers

Which type of T cells recognize soluble antigens and release IFN-γ to activate macrophages, causing tissue injury?

<p>TH1 cells (D)</p> Signup and view all the answers

Which cytokines are produced by TH2 cells?

<p>IL-4 and IL-5 (C)</p> Signup and view all the answers

What is the role of Tfh cells in the immune response?

<p>Helping B cell switching (B)</p> Signup and view all the answers

Which type of immune cells are responsible for direct cytotoxicity in Type IV hypersensitivity reactions?

<p>CD8+ T cells (D)</p> Signup and view all the answers

Which type of T cell is associated with CD8+ coreceptor molecules?

<p>Cytotoxic T cells (A)</p> Signup and view all the answers

What is the primary role of B cells in the immune system?

<p>Producing antibodies (B)</p> Signup and view all the answers

Which type of shock is associated with third spacing of fluids?

<p>Hypovolaemic shock (C)</p> Signup and view all the answers

Curling ulcers are most commonly associated with which condition?

<p>Burns (B)</p> Signup and view all the answers

What type of risk is associated with cancer, according to the text?

<p>Risk of cardiac arrhythmia (B)</p> Signup and view all the answers

What is the term for SCC that arises from non-healing wounds, such as burns?

<p>Marjolin ulcer (D)</p> Signup and view all the answers

In electrical burns, what is a common offending agent-related complication?

<p>Arrhythmia (B)</p> Signup and view all the answers

Which of the following is a potential risk associated with frictional injuries?

<p>Risk of TBI (B)</p> Signup and view all the answers

Which classification of burn involves healing that can take several months with long-term scarring?

<p>2nd degree deep partial-thickness burn (C)</p> Signup and view all the answers

Inadequate end organ perfusion can lead to which of the following conditions?

<p>Acute kidney injury (A)</p> Signup and view all the answers

What is the primary concern when discussing the 'shocked state' according to the text?

<p>Curling ulcer (C)</p> Signup and view all the answers

"Post-burn hypermetabolism" is a complication typically seen in which type of burn?

<p>3rd degree burn (C)</p> Signup and view all the answers

Which of the following is NOT a type of risk mentioned in the text?

<p>Frictional - risk of Curling ulcer (D)</p> Signup and view all the answers

Which condition is primarily associated with inhalation injury, as discussed in the text?

<p>Increased work of breathing (C)</p> Signup and view all the answers

Which of the following is a consequence of thermal burns with a high total body surface area (TBSA) involvement?

<p>Massive inflammatory response leading to systemic inflammatory response syndrome (SIRS) (D)</p> Signup and view all the answers

What is the primary cause of hypovolaemic shock in patients with extensive burns?

<p>Increased vascular permeability leading to fluid loss (C)</p> Signup and view all the answers

Which of the following is a risk factor for compartment syndrome in patients with circumferential burns?

<p>Formation of eschars (dried, necrotic skin tissue) (B)</p> Signup and view all the answers

Which type of shock is associated with radiation burns?

<p>Radiation poisoning (A)</p> Signup and view all the answers

Which of the following is a consequence of the postburn hypermetabolic state?

<p>Significant weight loss and muscle wasting (D)</p> Signup and view all the answers

Which zone of burn injury is characterized by coagulative necrosis and is considered irreversible?

<p>Zone of coagulation (C)</p> Signup and view all the answers

Which type of shock is characterized by a decrease in systemic vascular resistance?

<p>Distributive shock (B)</p> Signup and view all the answers

What is the main cause of cardiogenic shock?

<p>Myocardial infarction (heart attack) (C)</p> Signup and view all the answers

Which of the following is a common symptom of hypovolemic shock?

<p>Dehydration (C)</p> Signup and view all the answers

Which type of shock is characterized by a critical reduction in blood flow, leading to cellular dysfunction?

<p>All of the above (D)</p> Signup and view all the answers

Which type of shock is associated with third spacing of fluids?

<p>Septic shock (A)</p> Signup and view all the answers

What is the primary treatment for hypovolemic shock?

<p>Fluid resuscitation (C)</p> Signup and view all the answers

What is the primary characteristic of septic shock?

<p>Fever and chills (D)</p> Signup and view all the answers

Which type of shock is commonly associated with widespread inflammation and organ damage?

<p>Septic shock (A)</p> Signup and view all the answers

What is the main focus of treatment for hypovolemic shock?

<p>Providing fluid resuscitation (D)</p> Signup and view all the answers

Which type of shock involves addressing the underlying cause and often using vasopressors for treatment?

<p>Hypovolemic shock (D)</p> Signup and view all the answers

What distinguishes distributive shock from other types of shock?

<p>Widespread inflammation and organ damage (C)</p> Signup and view all the answers

What is a potential complication of mismanaged fluid resuscitation?

<p>Hyperkalemia (C)</p> Signup and view all the answers

Which type of shock is characterized by obstructed blood flow leading to decreased cardiac output?

<p>Cardiogenic shock (A)</p> Signup and view all the answers

What type of solution is commonly used for fluid resuscitation to improve organ perfusion?

<p>Isotonic crystalloid solution (A)</p> Signup and view all the answers

In which type of shock does inadequate cardiac function lead to systemic hypoperfusion?

<p>Cardiogenic shock (D)</p> Signup and view all the answers

Which of the following is a potential complication of fluid resuscitation in the context of hemorrhagic shock?

<p>Compartment syndrome (C)</p> Signup and view all the answers

What is the primary aim of fluid resuscitation in the context of cardiogenic shock?

<p>Improve organ perfusion (D)</p> Signup and view all the answers

What is the primary cause of obstructive shock?

<p>An obstruction in the blood vessels, preventing adequate circulation of blood (C)</p> Signup and view all the answers

Which of the following conditions can lead to cardiogenic shock?

<p>Myocardial infarction (B)</p> Signup and view all the answers

What is a common symptom of obstructive shock that may be observed?

<p>Cool extremities (A)</p> Signup and view all the answers

Which of the following is NOT a potential treatment approach for obstructive shock?

<p>Fluid resuscitation (C)</p> Signup and view all the answers

What is a common symptom of cardiogenic shock that may be observed?

<p>Shortness of breath (D)</p> Signup and view all the answers

Which type of shock is most likely to require fluid resuscitation as part of the treatment approach?

<p>Hypovolemic shock (A)</p> Signup and view all the answers

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