14 Questions
What is the mechanism of action of tetracyclines?
They inhibit protein synthesis
What is the main function of tetracyclines?
Inhibit protein synthesis
What type of bacteria are tetracyclines active against?
Gram-positive and gram-negative bacteria
What type of bacteria are tetracyclines active against?
Both gram-positive and gram-negative bacteria
How many mechanisms of resistance to tetracycline analogs are there?
Three
How many mechanisms of resistance to tetracycline analogs are there?
Three
What is the difference between tetracyclines in terms of their absorption and elimination?
They differ in their absorption after oral administration and in their elimination
In which body fluids are tetracyclines not distributed widely?
Cerebrospinal fluid
Where are tetracyclines distributed in the body?
Widely to tissues and body fluids except for cerebrospinal fluid
Where are tetracyclines excreted mainly?
Bile
How are tetracyclines excreted from the body?
Mainly in bile and urine
How are tetracyclines classified?
As short-acting, intermediate-acting, or long-acting
How are tetracyclines classified?
Short-acting, intermediate-acting, or long-acting
What is a potential side effect of tetracyclines?
Damage to growing bones and teeth
Study Notes
- Tetracyclines are antibiotics that inhibit protein synthesis.
- They are active against many gram-positive and gram-negative bacteria.
- There are three mechanisms of resistance to tetracycline analogs.
- Tetracyclines differ in their absorption after oral administration and in their elimination.
- Tetracyclines are 40–80% bound by serum proteins.
- Tetracyclines are distributed widely to tissues and body fluids except for cerebrospinal fluid.
- They cross the placenta to reach the fetus and are excreted in milk.
- Tetracyclines are excreted mainly in bile and urine.
- Tetracyclines are classified as short-acting, intermediate-acting, or long-acting.
- Tetracyclines can damage growing bones and teeth.
Think you know everything there is to know about tetracyclines? Test your knowledge with our quiz! From their mechanisms of resistance to their absorption and elimination, this quiz will cover all the key facts about tetracyclines. Plus, we'll dive into the different classifications of tetracyclines and the potential risks associated with their use. Perfect for students, healthcare professionals, and anyone interested in antibiotics and their effects on the body.
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