Tetanus Pathogenesis and Clinical Features
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Questions and Answers

What is a characteristic grimace of risus sardonicus in generalized tetanus?

  • Frowning face with clenched teeth and wrinkled forehead (correct)
  • Smiling face with an open mouth
  • Facial expression with drooping eyelids and a smile
  • Neutral face with an open mouth

    • What is a potential complication of generalized tetanus?

  • Respiratory failure and coma
  • Fracture of vertebral and long bones (correct)
  • Decreased heart rate and hypotension
  • Seizures and loss of consciousness

    • What is a characteristic of tetanospasms in generalized tetanus?

  • Regular, predictable, and long-lasting
  • Mild, brief, and symmetric
  • Severe, prolonged, and asymmetric
  • Intermittent, irregular, and unpredictable (correct)

    • What is a common mode of infection in neonatal tetanus?

    <p>Through an unhealed umbilical stump</p> Signup and view all the answers

    What is a characteristic symptom of neonatal tetanus?

    <p>Generalized weakness, poor sucking, and irritability</p> Signup and view all the answers

    What is the typical duration of spasms in generalized tetanus?

    <p>Several minutes to hours</p> Signup and view all the answers

    What is the estimated number of deaths worldwide in 1998 due to Tetanus?

    <p>Over 215,000</p> Signup and view all the answers

    Which of the following is a complication of Tetanus related to respiratory muscles?

    <p>Laryngospasm</p> Signup and view all the answers

    What is a common secondary infection seen in Tetanus patients in hospitals?

    <p>Hospital-acquired pneumonia</p> Signup and view all the answers

    In what type of climate is Tetanus most often found?

    <p>Hot and damp climates</p> Signup and view all the answers

    Which one of the following is a common complication of Tetanus in newborn infants with passive immunity?

    <p>Generalized tetanus</p> Signup and view all the answers

    How is Tetanus primarily transmitted?

    <p>Through contaminated wounds</p> Signup and view all the answers

    What is the primary mechanism by which tetanus toxin leads to muscle spasms?

    <p>By blocking the release of inhibitor neurotransmitters</p> Signup and view all the answers

    What is the typical duration of spasms in generalized tetanus?

    <p>3-4 weeks</p> Signup and view all the answers

    What is the correlation between the injury site and the incubation period?

    <p>The further the injury site from the CNS, the longer the incubation period</p> Signup and view all the answers

    What is the average time of symptom onset in neonatal tetanus?

    <p>7 days after birth</p> Signup and view all the answers

    What is a characteristic feature of local tetanus?

    <p>Fixed muscle rigidity confined to one area</p> Signup and view all the answers

    What is the typical progression of cephalic tetanus?

    <p>It may precede the onset of generalized tetanus</p> Signup and view all the answers

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