Complement Activation Pathways Quiz

Complement Activation

• The lectin pathway is initiated by the binding of lectins to carbohydrate molecules on microbial surfaces.

Complement Activation Proteins

• C5a plays a role in complement activation by attracting and activating phagocytic cells.

Membrane Attack Complex (MAC)

• The membrane attack complex (MAC) is composed of C5b, C6, C7, C8, and C9 proteins that assemble together to form a membrane-spanning pore.

Alternative Pathway

• The alternative pathway can be spontaneously activated in the absence of antibodies through the continuous low-level hydrolysis of C3.

C3b Role

• C3b plays a role in complement activation by serving as an opsonin, enhancing phagocytosis, and amplifying the complement response.

Membrane Attack Complex (MAC) Function

• The membrane attack complex (MAC) functions by forming a membrane-spanning pore in the target cell, leading to osmotic lysis and cell death.

Take our quiz on complement activation pathways to test your knowledge on the three different pathways: classical, alternative, and lectin. Learn how each pathway is triggered and the role of antibodies and lectins in activation. Put your knowledge to the test and challenge yourself with our quiz!