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Diabetes 2
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Diabetes 2

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Questions and Answers

What is diabetes and how does it affect the body's sugar processing?

Diabetes is a disease that affects how the body processes sugar. Type 2 diabetes is the most common and happens when the body doesn't produce enough insulin or the cells don't respond properly to it.

What are some complications that can arise from having diabetes?

Having diabetes can cause different complications like high or low blood sugar levels. Low levels of blood sugar can make you feel sick and dizzy, while high levels can cause thirst, blurry vision, and even lead to a life-threatening condition called ketoacidosis. Diabetes can also damage different parts of the body like the kidneys, eyes, and feet, which can lead to things like blindness and amputations.

What lifestyle factors are often linked with Type 2 diabetes?

Type 2 diabetes is often linked with obesity and lack of exercise.

What is the main cause of diabetes and how does it affect the body?

<p>The main cause of diabetes is the inability of the body to use glucose (sugar) properly. This can lead to different chemical reactions happening in the liver. Diabetes can affect different parts of the body, like the nerves, blood vessels, and retina.</p> Signup and view all the answers

What are some of the consequences of diabetes on the body?

<p>Diabetes can have a negative impact on different parts of the body, such as the nerves, blood vessels, and retina.</p> Signup and view all the answers

What is the article's main objective and how does it encourage readers?

<p>The article's main objective is to educate readers about diabetes. It encourages readers to learn more about this disease by checking out the recommended resources provided.</p> Signup and view all the answers

What is diabetes and what causes it?

<p>Diabetes is a metabolic disorder resulting from insufficient insulin production or improper insulin response. Type 1 diabetes is caused by autoimmune destruction of pancreatic β-cells, while Type 2 diabetes results from a combination of insulin resistance and reduced insulin production.</p> Signup and view all the answers

What is hyperglycemia and how does it relate to diabetes?

<p>Hyperglycemia is a condition characterized by high levels of glucose in the blood. It is a common symptom of diabetes and occurs when the body fails to produce enough insulin or when cells in the body do not react to insulin properly.</p> Signup and view all the answers

What factors are strongly associated with Type 2 diabetes?

<p>Type 2 diabetes is strongly associated with obesity and a sedentary lifestyle.</p> Signup and view all the answers

What are the consequences of insulin dysfunction, and how can hypoglycemia be remedied?

<p>Consequences of insulin dysfunction include hyperglycemia and hypoglycemia. Hypoglycemia can be remedied by consuming carbohydrates.</p> Signup and view all the answers

What is the most common complication of diabetes, and how is it related to disease duration?

<p>The most common complication of diabetes is diabetic retinopathy (DR), which is more common as the duration of the disease increases.</p> Signup and view all the answers

What is ketoacidosis, and when does it occur in relation to glucose availability?

<p>Ketoacidosis is a life-threatening condition that occurs when there is an absence of available glucose for cells, leading to abnormal fat metabolism and a build-up of ketones and blood acidosis.</p> Signup and view all the answers

What is the role of glucagon in diabetes?

<p>The body adapts to use alternative sources of energy, such as glucagon, when insulin is not working correctly.</p> Signup and view all the answers

What is the consequence of the lack of PFKII and Fructose 2,6BP metabolite in glucose metabolism?

<p>It prevents glucose from being metabolized efficiently.</p> Signup and view all the answers

What are the consequences of excess glucose in diabetes?

<p>It can lead to the generation of sorbitol by Aldose Reductase, causing depletion of NADPH, poor control of reactive oxygen species, and hypertonic conditions.</p> Signup and view all the answers

What are the fasting adaptations that can occur in diabetes, and what does the liver produce during these adaptations?

<p>During fasting adaptations in diabetes, the liver can produce glucose, ketone bodies, and VLDL lipoproteins.</p> Signup and view all the answers

What is the difference in medication requirements between type 1 and type 2 diabetes?

<p>Type 1 diabetes usually requires insulin injections, while type 2 diabetes may require insulin medication if it becomes progressive.</p> Signup and view all the answers

What are the key actions that can help prevent or delay the onset of diabetic complications?

<p>Maintaining a healthy lifestyle and controlling blood glucose levels are crucial to managing diabetes and preventing its complications.</p> Signup and view all the answers

What is the difference between Type 1 and Type 2 Diabetes in terms of pathophysiology and onset?

<p>Type 1 Diabetes results from pancreatic ß-cell destruction and exhibits an acute onset involving ketoacidosis, while Type 2 Diabetes occurs when the body does not produce enough insulin or is resistant to insulin; it is associated with obesity and a sedentary lifestyle.</p> Signup and view all the answers

What are the symptoms of hyperglycemia in diabetes?

<p>Symptoms of hyperglycemia in diabetes include increased thirst, tiredness, frequent urination, and blurry vision.</p> Signup and view all the answers

What are the potential complications of diabetic ketoacidosis?

<p>Diabetic ketoacidosis can lead to acidosis, vomiting, hypotension, dehydration, and glycosuria. Atherosclerosis and other complications can arise as well.</p> Signup and view all the answers

What is the role of aldose reductase in the pathophysiology of diabetes?

<p>Aldose reductase generates sorbitol from glucose, which depletes NADPH and leads to hypertonic conditions in diabetes.</p> Signup and view all the answers

What are some acute complications of diabetes?

<p>Hypoglycemia or hyperglycemia can lead to ketoacidosis and diabetic coma without proper treatment.</p> Signup and view all the answers

What are some chronic complications of diabetes?

<p>Hypertension, atherosclerosis, stroke, nephropathy, peripheral neuropathy, and infections are chronic complications of diabetes.</p> Signup and view all the answers

What are some common complications of diabetes?

<p>Complications of diabetes can include nephropathy, diabetic retinopathy, sensorimotor neuropathy, peripheral vascular disease, foot ulcers, and increased risk of infections.</p> Signup and view all the answers

What are some long-term damaging effects of continual hyperglycemia in diabetes?

<p>Long-term damaging effects of continual hyperglycemia in diabetes can include heart disease and stroke, nerve damage, retinopathy, kidney disease, and foot problems.</p> Signup and view all the answers

What is the 'fasting mode' present in diabetes and what are its consequences?

<p>The 'fasting mode' present in diabetes leads to the biochemical consequences of the liver producing glucose, ketone bodies, and VLDL lipoproteins.</p> Signup and view all the answers

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