Neoplasm I

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Which one of the following characteristics best distinguishes the peripheral 'coin lesion' in the right mid-lung field as a neoplasm, rather than a granuloma?

Necrosis

Rapid increase in size

Recurrence following excision (correct)

Sensitivity to radiation or chemotherapy

Which one of the following best describes the growth pattern of the peripheral 'coin lesion' in the right mid-lung field?

Recurrence following excision

Uncontrolled (autonomous) growth (correct)

Necrosis

Rapid increase in size

Which one of the following best describes the growth pattern of the firm nodule on the dome of the uterus?

Uncontrolled (autonomous) growth

Recurrence following excision

Necrosis

Rapid increase in size (correct)

Which one of the following best describes the clinical presentation of the patient with the firm nodule on the dome of the uterus?

Asymptomatic Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes the peripheral 'coin lesion' in the right mid-lung field as a neoplasm, rather than a granuloma?

Uncontrolled (autonomous) growth Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes the firm nodule on the dome of the uterus as a neoplasm?

Rapid increase in size Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes the peripheral 'coin lesion' in the right mid-lung field as a neoplasm?

Uncontrolled (autonomous) growth Signup and view all the answers

Which suffix is added to the tissue type to name benign tumors?

-oma Signup and view all the answers

Which of the following is an example of a benign tumor?

Fibroadenoma Signup and view all the answers

What is the term for tumors that are capable of invasion and destruction of adjacent normal tissues?

Malignant tumors Signup and view all the answers

Which suffix is added to the presumed histogenetic origin to name malignant tumors of epithelial origin?

-carcinoma Signup and view all the answers

Which term refers to the lack of differentiation in a tumor?

Anaplasia Signup and view all the answers

Which of the following is a morphologic predictor of malignancy at the cellular level?

Nuclear hyperchromasia Signup and view all the answers

Which type of spread is typically seen in intraperitoneal seeding of tumors?

Seeding Signup and view all the answers

Which of the following is an example of local invasion by a malignant tumor?

Lymphatic infiltration by breast adenocarcinoma Signup and view all the answers

Which of the following is a characteristic of malignant tumors?

Blood supply influences growth rate Signup and view all the answers

Which of the following is the most likely diagnosis for the uterine nodule that was examined microscopically and revealed benign smooth muscle cells?

Leiomyoma Signup and view all the answers

A healthy 22-year-old woman has a routine physical examination and a discreet, firm, rubbery, movable mass is found in the left breast. She has no axillary lymphadenopathy. The skin overlying the breast and the nipple appear normal. Which of the following neoplasms is most likely to be present?

Fibroadenoma Signup and view all the answers

A 32-year-old woman with dull pelvic pain undergoes an abdominal ultrasound that reveals an 8 cm mass involving the right ovary. The mass is surgically excised and is smooth, not adherent to surrounding structures, and filled with hair on sectioning. Microscopically, there is squamous epithelium, tall columnar glandular epithelium, cartilage, and fibrous connective tissue. What is the most likely diagnosis for this mass?

Teratoma Signup and view all the answers

A 62-year-old man complains of pain on urination. On cystoscopy, a slightly erythematous 1 cm diameter area is seen on the bladder wall. This area is biopsied and microscopically, the epithelium shows cells with marked hyperchromatism and increased nuclear/cytoplasmic ratio involving the full thickness. However, these changes are confined to the epithelium above the basement membrane. What best describes this process?

Carcinoma in situ Signup and view all the answers

A lump is felt in the right breast of a 56-year-old woman. The physician palpates an irregular 3 cm mass that is fixed to the overlying skin, which is retracted. A mastectomy is performed and the pathologist finds a 3 x 3.5 cm ovoid mass that infiltrates into the surrounding fibrofatty breast stroma. The mass is firm, white, and has a fibrous consistency. What feature is demonstrated by the gross appearance of this mass?

Desmoplasia Signup and view all the answers

A biopsy is performed on a patient with a mass lesion that proves to be a neoplasm. Of the following histopathologic findings, which one best indicates that the neoplasm is malignant?

Invasion Signup and view all the answers

A 60-year-old man with a history of cigarette smoking has a chronic cough and recent weight loss. A chest radiograph reveals a right hilar mass, and sputum cytology shows atypical, hyperchromatic squamous cells. What is the most common initial pathway of spread for this lesion?

Bronchi Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes teratomas from other neoplasms?

Presence of heterotopic rest of cells Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes choristoma from other congenital anomalies?

Presence of benign cells in an abnormal location Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes hamartoma from other benign masses?

Presence of disorganized tissue indigenous to the particular site Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes mesothelioma from other malignancies?

Presence of malignancy arising from the mesothelial cells lining the abdominal, pleural and pericardial cavities Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes myxoma from other benign neoplasms?

Presence of a benign neoplasm with an edematous (myxoid) gross appearance Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes carcinoma in-situ from other epithelial lesions?

Presence of neoplastic transformation of cells Signup and view all the answers

Which one of the following best describes the biologic characteristic that distinguishes invasive malignancy from other malignancies?

Presence of tissue invasion Signup and view all the answers

Which one of the following neoplasms arises from totipotential germ cells?

Teratoma Signup and view all the answers

Which one of the following is a benign mass of disorganized tissue indigenous to a particular site?

Hamartoma Signup and view all the answers

Which one of the following is an epithelial lesion confined by a basement membrane, indicating an in-situ lesion?

Carcinoma in-situ Signup and view all the answers

Which one of the following refers to microscopic loss of the structural and functional differentiation of tumor cells?

Anaplasia Signup and view all the answers

Which one of the following features are seen in malignant cells but can also be seen in reactive cells?

Atypia Signup and view all the answers

Which one of the following is the typical initial spread pattern of squamous cell carcinoma of the lung?

Spread via lymphatics to lymph nodes Signup and view all the answers

Which one of the following characteristics is a defining feature of neoplasms?

Differentiation and anaplasia Signup and view all the answers

Neoplasm I

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Questions and Answers

Which one of the following characteristics best distinguishes the peripheral 'coin lesion' in the right mid-lung field as a neoplasm, rather than a granuloma?

Which one of the following best describes the growth pattern of the peripheral 'coin lesion' in the right mid-lung field?

Which one of the following best describes the growth pattern of the firm nodule on the dome of the uterus?

Which one of the following best describes the clinical presentation of the patient with the firm nodule on the dome of the uterus?

Which one of the following best describes the biologic characteristic that distinguishes the peripheral 'coin lesion' in the right mid-lung field as a neoplasm, rather than a granuloma?

Which one of the following best describes the biologic characteristic that distinguishes the firm nodule on the dome of the uterus as a neoplasm?

Which one of the following best describes the biologic characteristic that distinguishes the peripheral 'coin lesion' in the right mid-lung field as a neoplasm?

Which suffix is added to the tissue type to name benign tumors?

Which of the following is an example of a benign tumor?

What is the term for tumors that are capable of invasion and destruction of adjacent normal tissues?

Which suffix is added to the presumed histogenetic origin to name malignant tumors of epithelial origin?

Which term refers to the lack of differentiation in a tumor?

Which of the following is a morphologic predictor of malignancy at the cellular level?

Which type of spread is typically seen in intraperitoneal seeding of tumors?

Which of the following is an example of local invasion by a malignant tumor?

Which of the following is a characteristic of malignant tumors?

Which of the following is the most likely diagnosis for the uterine nodule that was examined microscopically and revealed benign smooth muscle cells?

A healthy 22-year-old woman has a routine physical examination and a discreet, firm, rubbery, movable mass is found in the left breast. She has no axillary lymphadenopathy. The skin overlying the breast and the nipple appear normal. Which of the following neoplasms is most likely to be present?

A biopsy is performed on a patient with a mass lesion that proves to be a neoplasm. Of the following histopathologic findings, which one best indicates that the neoplasm is malignant?

A 60-year-old man with a history of cigarette smoking has a chronic cough and recent weight loss. A chest radiograph reveals a right hilar mass, and sputum cytology shows atypical, hyperchromatic squamous cells. What is the most common initial pathway of spread for this lesion?

Which one of the following best describes the biologic characteristic that distinguishes teratomas from other neoplasms?

Which one of the following best describes the biologic characteristic that distinguishes choristoma from other congenital anomalies?

Which one of the following best describes the biologic characteristic that distinguishes hamartoma from other benign masses?

Which one of the following best describes the biologic characteristic that distinguishes mesothelioma from other malignancies?

Which one of the following best describes the biologic characteristic that distinguishes myxoma from other benign neoplasms?

Which one of the following best describes the biologic characteristic that distinguishes carcinoma in-situ from other epithelial lesions?

Which one of the following best describes the biologic characteristic that distinguishes invasive malignancy from other malignancies?

Which one of the following neoplasms arises from totipotential germ cells?

Which one of the following is a benign mass of disorganized tissue indigenous to a particular site?

Which one of the following is an epithelial lesion confined by a basement membrane, indicating an in-situ lesion?

Which one of the following refers to microscopic loss of the structural and functional differentiation of tumor cells?

Which one of the following features are seen in malignant cells but can also be seen in reactive cells?

Which one of the following is the typical initial spread pattern of squamous cell carcinoma of the lung?

Which one of the following characteristics is a defining feature of neoplasms?

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