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Questions and Answers
What is a common feature of astrocytoma, IDH-mutant, grade 3?
What is a common feature of astrocytoma, IDH-mutant, grade 3?
- Microvascular proliferation
- Necrosis
- Prominent cytologic atypia
- Fibrillary background with mitotic figures (correct)
What distinguishes astrocytoma, IDH-mutant, grade 4 from grade 3?
What distinguishes astrocytoma, IDH-mutant, grade 4 from grade 3?
- Absence of mitotic figures
- Presence of homozygous deletion of CDKN2A &/or CDKN2B (correct)
- More nuclear pleomorphism
- Lack of astrocytic cell processes in the background
Which feature is NOT present in astrocytoma, IDH-mutant, grade 3?
Which feature is NOT present in astrocytoma, IDH-mutant, grade 3?
- Mitotic activity
- Microvascular proliferation (correct)
- Fibrillary background
- Enlarged irregular nuclei
What type of stain is used to identify tumor cells in astrocytoma?
What type of stain is used to identify tumor cells in astrocytoma?
In astrocytoma, what protein is used to identify the glial cells?
In astrocytoma, what protein is used to identify the glial cells?
In astrocytoma, IDH-mutant, grade 4, which feature distinguishes it from grade 3?
In astrocytoma, IDH-mutant, grade 4, which feature distinguishes it from grade 3?
Which characteristic is NOT typically found in astrocytoma, IDH-mutant, grade 3?
Which characteristic is NOT typically found in astrocytoma, IDH-mutant, grade 3?
What cellular feature is commonly observed in astrocytoma, IDH-mutant, grade 4?
What cellular feature is commonly observed in astrocytoma, IDH-mutant, grade 4?
Which stain is positive in tumor cells of astrocytoma?
Which stain is positive in tumor cells of astrocytoma?
What is a distinguishing feature of astrocytoma, IDH-mutant, grade 4 compared to lower grades?
What is a distinguishing feature of astrocytoma, IDH-mutant, grade 4 compared to lower grades?
Which factor plays a significant role in grading astrocytomas?
Which factor plays a significant role in grading astrocytomas?
What feature is NOT typically observed in astrocytoma, IDH-mutant, grade 3?
What feature is NOT typically observed in astrocytoma, IDH-mutant, grade 3?
Which characteristic is common to both astrocytoma, IDH-mutant, grades 3 and 4?
Which characteristic is common to both astrocytoma, IDH-mutant, grades 3 and 4?
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