Neoplasia I: Introduction & Overview of Benign and Malignant Neoplasms

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22 Questions

What is the most common type of cancer in Ireland?

Bowel cancer

Which term is used to describe cancer cells that have formed but not yet spread out of the epithelium?

Carcinoma in situ

What is the distinguishing characteristic of benign neoplasms?

Microscopical assessment of cell morphology

What term is used to describe the spread of cancer from the primary site to a distant site?

Metastasis

What pathology assessment role involves microscopical assessment of cell morphology and tissue architecture, such as maturation of the epithelium?

Differentiating between benign and malignant neoplasms

What feature indicates malignant cells during microscopical assessment?

Pleomorphism

Why is the specimen 'inked' during breast carcinoma surgery?

To assess the extent of local invasion

What is the term for the capability of malignant neoplasms to spread from the primary site to a distant site?

'Metastasis'

'Pleomorphism' and increased mitotic activity are characteristics of which type of neoplasm?

'Leiomyosarcoma'

What is the distinguishing feature of carcinoma in situ?

Not invading through basement membrane

What is the main difference between neoplasms and hyperplasia?

Neoplasms involve abnormal cell growth, while hyperplasia involves increased number of normal cells

What distinguishes a hamartoma from a neoplasm?

A hamartoma is a developmental error/malformation rather than a neoplasm

What is the difference between benign and malignant neoplasms?

Benign neoplasms do not invade nearby tissues, while malignant neoplasms can invade and spread to other parts of the body

What does the term 'neoplasm' mean?

'New growth'

What is the distinguishing feature of a carcinoma in situ?

The tumor has not invaded nearby tissues

What is the characteristic that indicates malignant cells during microscopical assessment?

Pleomorphism and increased mitotic activity

What is the difference between a neoplasm and a tumor?

A neoplasm is a new growth of abnormal cells, while a tumor is a swelling or condition of being swollen

What is the definition of hyperplasia?

Increased number of normal cells

What best describes a hamartoma?

A benign malformation rather than a neoplasm

How can neoplasm be classified?

As either benign or malignant

Which term refers to an increased number of normal cells?

Hyperplasia

What do the Greek words 'neo' and 'plasma' mean in the term 'neoplasm'?

'New' and 'growth'

Test your knowledge on the introduction and overview of benign and malignant neoplasms, including the definition, differences between neoplasms and tumors, as well as between benign and malignant neoplasms. This quiz is based on the Year 1 Pathology course at RCSI Royal College of Surgeons in Ireland, taught by Professor Paul Murray in 2024.

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