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Teratology Lecture 2: Genetic Anomalies

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Questions and Answers

What percentage of trisomy 21 pregnancies conceived end as spontaneous abortions or stillbirths?

90%

50%

20%

80% (correct)

What is the approximate incidence of Down syndrome amongst livebirths?

1/25000

1/8000

1/800 (correct)

1/1000

What is the most common cause of trisomy 21?

Nondisjunction event (correct)

Genetic inheritance

Environmental factors

Mutations

What percentage of trisomy 13 conceptuses result in livebirths?

1-2% (B) Signup and view all the answers

What is the approximate incidence of Patau syndrome amongst liveborn infants?

1/25000 (B) Signup and view all the answers

What percentage of trisomy 18 conceptuses end as early spontaneous abortions?

95% (A) Signup and view all the answers

What percentage of spontaneous abortions will have trisomy 18?

1% (D) Signup and view all the answers

What is the approximate incidence of Edward's syndrome amongst livebirths?

1/8000 (B) Signup and view all the answers

What percentage of stillbirths will have trisomy 21?

1% (C) Signup and view all the answers

What percentage of spontaneous abortions will have trisomy 21?

1% (A) Signup and view all the answers