Teratology Lecture 2: Genetic Anomalies
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Questions and Answers

What percentage of trisomy 21 pregnancies conceived end as spontaneous abortions or stillbirths?

  • 90%
  • 50%
  • 20%
  • 80% (correct)
  • What is the approximate incidence of Down syndrome amongst livebirths?

  • 1/25000
  • 1/8000
  • 1/800 (correct)
  • 1/1000
  • What is the most common cause of trisomy 21?

  • Nondisjunction event (correct)
  • Genetic inheritance
  • Environmental factors
  • Mutations
  • What percentage of trisomy 13 conceptuses result in livebirths?

    <p>1-2%</p> Signup and view all the answers

    What is the approximate incidence of Patau syndrome amongst liveborn infants?

    <p>1/25000</p> Signup and view all the answers

    What percentage of trisomy 18 conceptuses end as early spontaneous abortions?

    <p>95%</p> Signup and view all the answers

    What percentage of spontaneous abortions will have trisomy 18?

    <p>1%</p> Signup and view all the answers

    What is the approximate incidence of Edward's syndrome amongst livebirths?

    <p>1/8000</p> Signup and view all the answers

    What percentage of stillbirths will have trisomy 21?

    <p>1%</p> Signup and view all the answers

    What percentage of spontaneous abortions will have trisomy 21?

    <p>1%</p> Signup and view all the answers

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