Teratogenesis: Factors and Principles

Play an AI-generated podcast conversation about this lesson

Which of the following genetic anomalies is commonly associated with the short arm deletion of chromosome 5?

Turner syndrome

Cri du chat syndrome (correct)

Down syndrome

Klinefelter syndrome

Which teratogenic drug, if used during pregnancy, can lead to birth defects like cataracts and deafness?

Thalidomide (correct)

Valproic acid

Warfarin

Halofantrin Hcl

What is the term for the error in cell division that leads to numerical chromosomal abnormalities like Down syndrome?

Duplication

Translocation

Nondisjunction (correct)

Inversion

What perinatal diagnosis method involves the sampling of amniotic fluid for genetic testing?

Amniocentesis Signup and view all the answers

Exposure to which antihypertensive drug during pregnancy can have teratogenic effects?

ACE Inhibitors Signup and view all the answers

Which virus can cause hepatomegaly and hydrancephaly when contracted by a pregnant woman?

Herpes simplex virus Signup and view all the answers

What is the term used to describe developmental disorders present at birth?

Congenital anomalies Signup and view all the answers

During which weeks of gestation do malformations typically occur?

3rd to 8th weeks Signup and view all the answers

What type of anomaly is characterized by morphological alterations of already formed structures due to destructive processes?

Disruption Signup and view all the answers

Which teratogenic effects occur due to environmental and/or genetic factors acting independently or together?

Malformation Signup and view all the answers

What are the four clinically significant types of congenital anomalies mentioned in the text?

Malformation, Disruption, Deformation, Dysplasia Signup and view all the answers

Which term refers to specific abnormality resulting from disruption of normal developmental processes?

'Disruption' Signup and view all the answers

Which factor is NOT listed as a potential cause of anomalies in the text?

Bacterial infections Signup and view all the answers

What is a critical principle in teratogenesis according to the text?

Random exposure to chemicals during pregnancy Signup and view all the answers

What is recommended when dealing with diseases during pregnancy?

Use drugs with known effects on pregnancy without signs of embryotoxicity Signup and view all the answers

What is a key aspect to consider during maternal serum screening according to the text?

Can detect certain conditions that may require further testing Signup and view all the answers

What is a key consideration for amniocentesis procedure discussed in the text?

Provides genetic information about the fetus Signup and view all the answers

Why are ultrasound scans used during pregnancy according to the text?

To monitor fetal growth and development, detect abnormalities, and estimate gestational age Signup and view all the answers