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Questions and Answers
What is a key ideal property of fillers in tablet formulation?
What is a key ideal property of fillers in tablet formulation?
- Highly reactive with the active pharmaceutical ingredient (API)
- Expensive and commercially unviable
- Chemically inert and compatible with drug and other excipients (correct)
- Hygroscopic and moisture-absorbent
Why is it important for fillers to be non-hygroscopic in tablet formulation?
Why is it important for fillers to be non-hygroscopic in tablet formulation?
- To enhance their solubility in water for rapid dissolution of the tablet
- To prevent them from taking up moisture and causing instability in the tablet (correct)
- To ensure they have good flow properties and are easy to compress
- To improve their taste and make the tablet more palatable
Which of the following is the most common filler in tablet formulations?
Which of the following is the most common filler in tablet formulations?
- Sorbitol
- Cellulose
- Mannitol
- Lactose (correct)
What is the role of fillers in tablet formulation?
What is the role of fillers in tablet formulation?
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