4 Immunology
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Questions and Answers

Which type of T cells release IL-2, IL-4, and interferon-gamma?

  • Suppressor T cells (CD8)
  • Cytotoxic T cells (CD8)
  • Natural killer cells
  • Helper T cells (CD4) (correct)

What is the main function of IL-4 released by helper T cells?

  • Stimulates cytotoxic T cells
  • Activates macrophages
  • Recognizes and attacks non–self-antigens
  • Causes B-cell maturation into plasma cells (correct)

Which type of T cells recognize and attack non–self-antigens attached to MHC class I receptors?

  • Natural killer cells
  • Helper T cells (CD4)
  • Suppressor T cells (CD8)
  • Cytotoxic T cells (CD8) (correct)

Which cells are involved in delayed-type hypersensitivity and bring in inflammatory cells by chemokine secretion?

<p>Helper T cells (B)</p> Signup and view all the answers

What is the main effector cell in cell-mediated immunity?

<p>Macrophages (C)</p> Signup and view all the answers

What is the main infection associated with defects in cell-mediated immunity?

<p>Viral infections (C)</p> Signup and view all the answers

Which cytokine stimulates B cells to become plasma cells?

<p>Interleukin-4 (IL-4) (A)</p> Signup and view all the answers

Which immunoglobulin is secreted with reinfection?

<p>IgG (C)</p> Signup and view all the answers

What is the main function of suppressor T cells (CD8)?

<p>To regulate CD4 and CD8 cells (A)</p> Signup and view all the answers

What is the purpose of an intradermal skin test (e.g. TB skin test)?

<p>To test for cell-mediated immunity (D)</p> Signup and view all the answers

Which type of hypersensitivity reaction involves IgE receptors on mast cells and basophils?

<p>Type I (D)</p> Signup and view all the answers

What is the most abundant antibody in the body responsible for the secondary immune response?

<p>IgG (D)</p> Signup and view all the answers

Which antibody is found in secretions, in Peyer’s patches in the gut, and in breast milk?

<p>IgA (A)</p> Signup and view all the answers

Which antibody is responsible for initial antibody secretion after exposure to an antigen (primary immune response)?

<p>IgM (A)</p> Signup and view all the answers

Which cells recognize cells that lack self-MHC and are part of the body’s natural immunosurveillance for cancer?

<p>Natural killer cells (D)</p> Signup and view all the answers

In T-cell and B-cell activation, what provides the costimulatory signal required after alloantigen binds to antigen-specific receptors?

<p>IL-1 (B)</p> Signup and view all the answers

Which type of infection leads to endocytosis of proteins, which get bound to class II MHC molecules and are recognized by CD4 helper T cells?

<p>Bacterial infection (D)</p> Signup and view all the answers
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