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Cytotoxic T-Cells and Antigen Specificity

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Cytotoxic T-Cells and Antigen Specificity

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Questions and Answers

Which pathway involves the translocation of ingested proteins into the cytosol for degradation by the proteasome before loading peptides onto MHC class I molecules?

Processing of antigens in the Golgi before loading onto MHC class I

Transport of peptides through TAP directly to MHC class I molecules

Presentation of cellular antigens by MHC class II molecules

Direct transport of antigens from the phagolysosome into a vesicular loading compartment (correct)

Which protein is responsible for inducing a conformational change in the alpha chain to form a quaternary complex with microglobulin?

Calreticulin

Tapasin

Proteasome

Calnexin (correct)

What is the role of TAP (transporter associated with antigen processing) in the antigen presentation pathway?

Transporting antigens from MHC-II to MHC-I molecules

Transporting peptides directly from the phagolysosome to the golgi apparatus

Binding directly to MHC class I molecules for peptide loading

Mediating the ATP-dependent process for introducing peptides into the endoplasmic reticulum (correct)

Where are MHC class I processed antigens delivered after loading?

<p>Golgi apparatus</p> Signup and view all the answers

Which pathway allows cytosolic antigens to be presented by MHC class II molecules?

<p>Presentation of cellular antigens by MHC class II molecules</p> Signup and view all the answers

Cytotoxic T-Cells and Antigen Specificity

Choose a study mode

Podcast

Questions and Answers

Which pathway involves the translocation of ingested proteins into the cytosol for degradation by the proteasome before loading peptides onto MHC class I molecules?

Which protein is responsible for inducing a conformational change in the alpha chain to form a quaternary complex with microglobulin?

What is the role of TAP (transporter associated with antigen processing) in the antigen presentation pathway?

Where are MHC class I processed antigens delivered after loading?

Which pathway allows cytosolic antigens to be presented by MHC class II molecules?

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