5 Questions
Which pathway involves the translocation of ingested proteins into the cytosol for degradation by the proteasome before loading peptides onto MHC class I molecules?
Direct transport of antigens from the phagolysosome into a vesicular loading compartment
Which protein is responsible for inducing a conformational change in the alpha chain to form a quaternary complex with microglobulin?
Calnexin
What is the role of TAP (transporter associated with antigen processing) in the antigen presentation pathway?
Mediating the ATP-dependent process for introducing peptides into the endoplasmic reticulum
Where are MHC class I processed antigens delivered after loading?
Golgi apparatus
Which pathway allows cytosolic antigens to be presented by MHC class II molecules?
Presentation of cellular antigens by MHC class II molecules
Explore the role of hyper variable regions in determining antigen specificity for CD8 Cytotoxic T-cells. Learn about the mechanisms of action for cytotoxic T-cells, including inducing apoptosis or secreting enzymes to kill diseased cells.
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