lecture 13 true and false quiz- immunology

Positive selection in the cortex is a key event in B cell maturation.

Chemokine-guided migration of B cells occurs during lymphocyte maturation.

Negative selection in the medulla is a process involved in T cell survival.

Selection and elimination occur at checkpoints as key events in B cell maturation.

Actions of the Pre-T cell receptor are essential for B cell development in the thymus.

Positive selection in the cortex ensures that only B cells with non-functional receptors undergo apoptosis.

Chemokine-guided migration of T cells only occurs during negative selection in the medulla.

Negative selection in the medulla leads to the elimination of T cells that recognize self-antigens too strongly.

T cell survival is promoted by apoptosis.

Lymphocyte maturation involves a random series of events that results in a limited range of diverse lymphocytes.

Positive selection is a crucial step in the maturation of B cells in the bone marrow.

Positive selection promotes survival of lymphocytes with strong interactions with self-antigens.

Negative selection eliminates T cells that bind weakly to self-antigens.

Clonal deletion occurs during positive selection.

Actions of the pre-T cell receptor are involved in B cell maturation.

During maturation, immature B cells may initially express two versions of the antigen receptor, one from each chromosome.

The pre-BCR promotes allelic exclusion during B cell maturation.

T cell maturation involves chemokine-guided migration to the thymus.

During B cell maturation, the expression of surrogate light chains continues in mature B cells.

One key event in T cell maturation is sequential rearrangement.

Positive selection in the cortex is a key event in T cell maturation.

Chemokine-guided migration of B cells occurs during lymphocyte maturation.

Negative selection in the medulla is a process involved in T cell survival.

T cell survival and apoptosis are regulated by the actions of the Pre-B cell receptor.

Lymphocyte maturation involves selection and elimination as key events in B cell maturation.

Receptor editing in B cells provides a mechanism to modify antigen receptor specificity and avoid autoreactivity.

T cell survival with strong reactivity to self-antigens is promoted by negative selection.

B cell maturation involves three rounds of sequential rearrangement of immunoglobulin (Ig) genes.

Key events in T cell maturation include sequential rearrangement of immunoglobulin genes.

Lymphocyte maturation ensures the generation of dysfunctional B cells incapable of recognizing antigens.

Positive selection in the cortex is a key event in T cell maturation.

Chemokine-guided migration of T cells occurs during positive selection in the medulla.

Negative selection in the medulla is a process involved in promoting T cell survival.

T cell survival is promoted by apoptosis.

Lymphocyte maturation involves a random series of events that results in a limited range of diverse lymphocytes.

Selection and elimination occur at checkpoints as key events in T cell maturation.

Actions of the Pre-B cell receptor are essential for T cell development in the thymus.

Key events in T cell maturation involve changes in surface marker expression.

Actions of the Pre-T cell receptor take place during B cell development in the thymus.

T cell development in the thymus involves rearrangement of antigen receptor genes in a stepwise manner.