Podcast
Questions and Answers
What is the function of CTLA-4 during T cell activation?
What is the function of CTLA-4 during T cell activation?
- Activates TCR signaling
- Triggers cell cycle progression
- Promotes T cell proliferation
- Inhibits T cell proliferation (correct)
Which molecule leads to cell cycle arrest during T cell activation?
Which molecule leads to cell cycle arrest during T cell activation?
- CD25
- CD40L
- CTLA-4 (correct)
- PD-1
What happens after 3 days of T cell expansion regarding proliferation?
What happens after 3 days of T cell expansion regarding proliferation?
- Proliferation stops
- Proliferation becomes uncontrolled
- Proliferation accelerates
- Proliferation slows down (correct)
Which molecule is involved in the formation of Effector Memory T cells (TEM)?
Which molecule is involved in the formation of Effector Memory T cells (TEM)?
What role does PD-1 play in T cell activation?
What role does PD-1 play in T cell activation?
Which molecule is responsible for promoting cytotoxicity in T cells?
Which molecule is responsible for promoting cytotoxicity in T cells?
What is the function of CD40L during T cell activation?
What is the function of CD40L during T cell activation?
Which signaling molecule downstream of the TCR leads to T cell activation?
Which signaling molecule downstream of the TCR leads to T cell activation?
What is the role of B7 in T cell activation?
What is the role of B7 in T cell activation?
Which molecule initiates the Ras pathway in T cell signaling?
Which molecule initiates the Ras pathway in T cell signaling?
What is the function of NFAT in T cell activation?
What is the function of NFAT in T cell activation?
Which enzyme is responsible for removing inhibitory phosphates from NFAT during T cell activation?
Which enzyme is responsible for removing inhibitory phosphates from NFAT during T cell activation?
What is the primary outcome of clonal expansion in T cell activation?
What is the primary outcome of clonal expansion in T cell activation?
Which molecule is responsible for activating PKC in T cell signaling?
Which molecule is responsible for activating PKC in T cell signaling?
What is the function of AP-1 in T cell activation signaling?
What is the function of AP-1 in T cell activation signaling?
Which enzyme is activated by Lck and leads to the activation of Ras pathway in T cell signaling?
Which enzyme is activated by Lck and leads to the activation of Ras pathway in T cell signaling?
What is the role of CD28 receptor in T cell activation signaling?
What is the role of CD28 receptor in T cell activation signaling?
