Systemic Connective Tissue Diseases Quiz
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Questions and Answers

What was the previous name for systemic connective tissue diseases, which does not reflect their essence?

  • Connective tissue diseases
  • Rheumatic diseases
  • Collagen diseases (correct)
  • Immunological disorders
  • What is the primary cause of connective tissue damage in rheumatic diseases?

  • Infection by virus
  • Genetic mutations
  • Physical factors such as cooling
  • Immunological homeostasis disruption (correct)
  • How many phases are involved in the manifestation of connective tissue damage in rheumatic diseases?

  • 6
  • 5
  • 3
  • 4 (correct)
  • What is the primary feature that distinguishes one rheumatic disease from another?

    <p>Predominant localization of changes in certain organs and tissues</p> Signup and view all the answers

    What is the common underlying mechanism of rheumatic diseases?

    <p>Immunopathological reactions</p> Signup and view all the answers

    What is the typical course of rheumatic diseases?

    <p>Chronic and undulating</p> Signup and view all the answers

    What type of cells typically surrounds rheumatic granulomas during development?

    <p>Lymphocytes</p> Signup and view all the answers

    What is the final phase of connective tissue disorganization in rheumatism?

    <p>Hyalinosis</p> Signup and view all the answers

    Which pathologist described the process of rheumatic nodule morphogenesis in more detail after Aschoff?

    <p>V.T.Talalaev</p> Signup and view all the answers

    Which of the following is NOT a form of rheumatic valvular endocarditis?

    <p>Destructive endocarditis</p> Signup and view all the answers

    What type of endocarditis is characterized by fibrosis and scarring as a prominent feature?

    <p>Fibroplastic endocarditis</p> Signup and view all the answers

    In rheumatic endocarditis, what is noted concerning the connective base of the endocardium?

    <p>Cell proliferation (granulomatosis)</p> Signup and view all the answers

    Which manifestations are characteristic of the acute warty type of rheumatic valvular endocarditis?

    <p>Endothelial damage and thrombotic deposits</p> Signup and view all the answers

    Which layer of the heart experiences pronounced dystrophic and inflammatory changes in rheumatism?

    <p>Endocardium</p> Signup and view all the answers

    Which connective tissue disorganization phase mainly results from cell proliferation and granulomas in rheumatism?

    <p>Secondary sclerosis</p> Signup and view all the answers

    What are the most characteristic changes in rheumatism when it comes to the specific organs affected?

    <p>Dystrophic and inflammatory changes in the heart and blood vessels</p> Signup and view all the answers

    What is the primary lesion location in rheumatism?

    <p>Heart and blood vessels</p> Signup and view all the answers

    What type of bacteria is responsible for the development of rheumatism?

    <p>β-hemolytic streptococcus group A</p> Signup and view all the answers

    What is the result of the immune response to streptococcal antigens in rheumatism?

    <p>Production of antibodies that cross-react with heart tissues</p> Signup and view all the answers

    What is the characteristic arrangement of cells in a typical rheumatic granuloma?

    <p>Palisade-shaped or fan-shaped</p> Signup and view all the answers

    What is the final stage of granuloma development in rheumatism?

    <p>Formation of scar tissue</p> Signup and view all the answers

    What is the role of macrophages in rheumatic granulomas?

    <p>To participate in the resorption of fibrinoid</p> Signup and view all the answers

    What is the duration of the granuloma development cycle in rheumatism?

    <p>3-4 months</p> Signup and view all the answers

    What is the result of the damage to connective tissue in rheumatism?

    <p>Breakdown of glycosaminoglycan complexes with proteins</p> Signup and view all the answers

    What is the characteristic feature of mucoid swelling in rheumatism?

    <p>Increased metachromatic reaction to glycosaminoglycans</p> Signup and view all the answers

    What are the dystrophic changes in nerve cells associated with in rheumatic vasculitis?

    <p>Foci of destruction of the brain tissue and hemorrhages</p> Signup and view all the answers

    What is the most common clinical form of rheumatism in children?

    <p>Cerebral form</p> Signup and view all the answers

    Which organ can develop autoimmunization in rheumatism?

    <p>Endocrine glands</p> Signup and view all the answers

    What is the most common complication associated with rheumatism?

    <p>Damage to the heart</p> Signup and view all the answers

    What can be a source of thromboembolism in rheumatism?

    <p>Warty endocarditis</p> Signup and view all the answers

    What can lead to decompensated heart disease in rheumatism patients?

    <p>Thromboembolic complications</p> Signup and view all the answers

    What is the primary characteristic of nodular productive (granulomatous) myocarditis?

    <p>The formation of rheumatic granulomas in the perivascular connective tissue of the myocardium</p> Signup and view all the answers

    What is the most common location of rheumatic granulomas in nodular myocarditis?

    <p>Left atrial appendage</p> Signup and view all the answers

    Which form of myocarditis is characterized by a slight focal infiltration of the myocardium by lymphocytes, histiocytes, and neutrophils?

    <p>Focal interstitial exudative myocarditis</p> Signup and view all the answers

    What is the primary characteristic of diffuse interstitial exudative myocarditis?

    <p>Significant infiltration of lymphocytes, histiocytes, neutrophils, and eosinophils</p> Signup and view all the answers

    Which form of myocarditis is associated with severe cardiosclerosis and can quickly end in decompensation and death of the patient?

    <p>Diffuse interstitial exudative myocarditis</p> Signup and view all the answers

    What is the primary characteristic of rheumatic vasculitis?

    <p>Fibrinoid changes in the walls of arteries and arterioles</p> Signup and view all the answers

    What is the primary characteristic of rheumatic endotheliosis?

    <p>The exfoliation of endothelial cells</p> Signup and view all the answers

    What is the primary characteristic of rheumatic polyarthritis?

    <p>The occurrence of a serous-fibrinous effusion in the joint cavity</p> Signup and view all the answers

    What is the primary characteristic of rheumatic nodules?

    <p>The existence of large nodes, which dissolve over time</p> Signup and view all the answers

    What is the primary characteristic of rheumatic nodules?

    <p>The existence of large nodes, which dissolve over time</p> Signup and view all the answers

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