Systemic Connective Tissue Diseases Quiz

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Questions and Answers

What was the previous name for systemic connective tissue diseases, which does not reflect their essence?

  • Connective tissue diseases
  • Rheumatic diseases
  • Collagen diseases (correct)
  • Immunological disorders

What is the primary cause of connective tissue damage in rheumatic diseases?

  • Infection by virus
  • Genetic mutations
  • Physical factors such as cooling
  • Immunological homeostasis disruption (correct)

How many phases are involved in the manifestation of connective tissue damage in rheumatic diseases?

  • 6
  • 5
  • 3
  • 4 (correct)

What is the primary feature that distinguishes one rheumatic disease from another?

<p>Predominant localization of changes in certain organs and tissues (D)</p> Signup and view all the answers

What is the common underlying mechanism of rheumatic diseases?

<p>Immunopathological reactions (A)</p> Signup and view all the answers

What is the typical course of rheumatic diseases?

<p>Chronic and undulating (D)</p> Signup and view all the answers

What type of cells typically surrounds rheumatic granulomas during development?

<p>Lymphocytes (B)</p> Signup and view all the answers

What is the final phase of connective tissue disorganization in rheumatism?

<p>Hyalinosis (A)</p> Signup and view all the answers

Which pathologist described the process of rheumatic nodule morphogenesis in more detail after Aschoff?

<p>V.T.Talalaev (A)</p> Signup and view all the answers

Which of the following is NOT a form of rheumatic valvular endocarditis?

<p>Destructive endocarditis (B)</p> Signup and view all the answers

What type of endocarditis is characterized by fibrosis and scarring as a prominent feature?

<p>Fibroplastic endocarditis (A)</p> Signup and view all the answers

In rheumatic endocarditis, what is noted concerning the connective base of the endocardium?

<p>Cell proliferation (granulomatosis) (C)</p> Signup and view all the answers

Which manifestations are characteristic of the acute warty type of rheumatic valvular endocarditis?

<p>Endothelial damage and thrombotic deposits (C)</p> Signup and view all the answers

Which layer of the heart experiences pronounced dystrophic and inflammatory changes in rheumatism?

<p>Endocardium (C)</p> Signup and view all the answers

Which connective tissue disorganization phase mainly results from cell proliferation and granulomas in rheumatism?

<p>Secondary sclerosis (A)</p> Signup and view all the answers

What are the most characteristic changes in rheumatism when it comes to the specific organs affected?

<p>Dystrophic and inflammatory changes in the heart and blood vessels (D)</p> Signup and view all the answers

What is the primary lesion location in rheumatism?

<p>Heart and blood vessels (C)</p> Signup and view all the answers

What type of bacteria is responsible for the development of rheumatism?

<p>β-hemolytic streptococcus group A (D)</p> Signup and view all the answers

What is the result of the immune response to streptococcal antigens in rheumatism?

<p>Production of antibodies that cross-react with heart tissues (A)</p> Signup and view all the answers

What is the characteristic arrangement of cells in a typical rheumatic granuloma?

<p>Palisade-shaped or fan-shaped (C)</p> Signup and view all the answers

What is the final stage of granuloma development in rheumatism?

<p>Formation of scar tissue (D)</p> Signup and view all the answers

What is the role of macrophages in rheumatic granulomas?

<p>To participate in the resorption of fibrinoid (D)</p> Signup and view all the answers

What is the duration of the granuloma development cycle in rheumatism?

<p>3-4 months (A)</p> Signup and view all the answers

What is the result of the damage to connective tissue in rheumatism?

<p>Breakdown of glycosaminoglycan complexes with proteins (B)</p> Signup and view all the answers

What is the characteristic feature of mucoid swelling in rheumatism?

<p>Increased metachromatic reaction to glycosaminoglycans (D)</p> Signup and view all the answers

What are the dystrophic changes in nerve cells associated with in rheumatic vasculitis?

<p>Foci of destruction of the brain tissue and hemorrhages (C)</p> Signup and view all the answers

What is the most common clinical form of rheumatism in children?

<p>Cerebral form (C)</p> Signup and view all the answers

Which organ can develop autoimmunization in rheumatism?

<p>Endocrine glands (C)</p> Signup and view all the answers

What is the most common complication associated with rheumatism?

<p>Damage to the heart (C)</p> Signup and view all the answers

What can be a source of thromboembolism in rheumatism?

<p>Warty endocarditis (A)</p> Signup and view all the answers

What can lead to decompensated heart disease in rheumatism patients?

<p>Thromboembolic complications (D)</p> Signup and view all the answers

What is the primary characteristic of nodular productive (granulomatous) myocarditis?

<p>The formation of rheumatic granulomas in the perivascular connective tissue of the myocardium (A)</p> Signup and view all the answers

What is the most common location of rheumatic granulomas in nodular myocarditis?

<p>Left atrial appendage (C)</p> Signup and view all the answers

Which form of myocarditis is characterized by a slight focal infiltration of the myocardium by lymphocytes, histiocytes, and neutrophils?

<p>Focal interstitial exudative myocarditis (D)</p> Signup and view all the answers

What is the primary characteristic of diffuse interstitial exudative myocarditis?

<p>Significant infiltration of lymphocytes, histiocytes, neutrophils, and eosinophils (B)</p> Signup and view all the answers

Which form of myocarditis is associated with severe cardiosclerosis and can quickly end in decompensation and death of the patient?

<p>Diffuse interstitial exudative myocarditis (C)</p> Signup and view all the answers

What is the primary characteristic of rheumatic vasculitis?

<p>Fibrinoid changes in the walls of arteries and arterioles (A)</p> Signup and view all the answers

What is the primary characteristic of rheumatic endotheliosis?

<p>The exfoliation of endothelial cells (C)</p> Signup and view all the answers

What is the primary characteristic of rheumatic polyarthritis?

<p>The occurrence of a serous-fibrinous effusion in the joint cavity (A)</p> Signup and view all the answers

What is the primary characteristic of rheumatic nodules?

<p>The existence of large nodes, which dissolve over time (A)</p> Signup and view all the answers

What is the primary characteristic of rheumatic nodules?

<p>The existence of large nodes, which dissolve over time (C)</p> Signup and view all the answers

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