Connective Tissue Diseases
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Questions and Answers

What is a common feature of connective tissue diseases mentioned in the text?

  • Single-organ involvement
  • Male predominance
  • Genetic predisposition (correct)
  • Acute disease course

    • Which of the following is not a connective tissue disease included in the text?

  • Wegener granulomatosis
  • Churg-Strauss syndrome
  • Temporal arteritis
  • Celiac disease (correct)

    • What is the significance of early diagnosis in connective tissue diseases?

  • To improve disease management and outcome (correct)
  • To ensure acute disease course
  • To achieve complete cure without relapse
  • To prevent genetic predisposition

    • What is a common characteristic of connective tissue diseases mentioned in the text?

    <p>Fluctuation between flares and remission</p> Signup and view all the answers

    Which connective tissue disease is characterized by Raynaud's phenomenon, skin thickening, and internal organ involvement?

    <p>Systemic sclerosis/Scleroderma (SS)</p> Signup and view all the answers

    Which type of arthritis often starts with involvement of the distal interphalangeal (DIP) joints?

    <p>Psoriatic arthritis</p> Signup and view all the answers

    What type of arthritis is histologically similar to rheumatoid arthritis but is usually less destructive?

    <p>Psoriatic arthritis</p> Signup and view all the answers

    Which form of arthritis can lead to 'telescopic fingers' due to the collapse of soft tissues?

    <p>Psoriatic arthritis</p> Signup and view all the answers

    Which type of arthritis is associated with 'pencil in cup' osteolysis on imaging?

    <p>Rheumatoid arthritis</p> Signup and view all the answers

    What is the most common type of chronic joint disease characterized by progressive erosion of articular cartilage?

    <p>Osteoarthritis</p> Signup and view all the answers

    'Sausage fingers/toes' are characteristic of which type of arthritis?

    <p>Psoriatic arthritis</p> Signup and view all the answers

    Which condition is characterized by deposition of monosodium urate crystals in joints leading to acute inflammatory monoarthritis?

    <p>Gout</p> Signup and view all the answers

    What is the most common affected joint in Gout?

    <p>First toe</p> Signup and view all the answers

    Which condition is characterized by calcification of fibrous and hyaline cartilage, leading to acute pain and swelling in joints such as knee, wrist, or shoulder?

    <p>Pseudogout</p> Signup and view all the answers

    Which type of crystals are characteristic of Pseudogout when viewed under polarized light?

    <p>Weakly positively birefringent rhomboid crystals</p> Signup and view all the answers

    Which condition is characterized by an infection in the joint, presenting as 'Hot red monoarthritis'?

    <p>Septic Arthritis</p> Signup and view all the answers

    What is the most common causative agent of septic arthritis in older children and adults?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    What is the term for deposits of monosodium urate crystals in the inflamed synovial membranes and periarticular tissue leading to cartilage damage and joint destruction in Gout?

    <p><strong>Gouty tophi</strong></p> Signup and view all the answers

    How do intra-articular crystals in Pseudogout induce an acute synovitis reaction?

    <p>By inducing neutrophil migration</p> Signup and view all the answers

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