18 Questions
Which type of tests are used to detect the presence of antibodies to treponemal antigens?
Treponemal tests
What is the method used for detecting reagin in the RPR test?
Addition of choline chloride
Which specimen type is used for the VDRL test?
Inactivated serum, CSF
What is the antigen detected in the ELISA test?
T.pallidum
At what temperature must the tests be performed?
Within the range of 23°C to 29°C
For how long are the small glass vials containing the suspension stable after opening?
3 months
How long does the primary stage of syphilis typically last?
28-42 days
What is the detection method for rashes that develop in syphilis patients?
None of the above
What are the symptoms of latent stage syphilis?
No symptoms may be present
How is Congenital Syphilis different from Venereal Syphilis?
Congenital Syphilis usually has CNS abnormalities
Which test is used to detect Neurosyphilis in patients?
None of the above
What are the lesions like in non-venereal endemic syphilis?
Elevated, granulomatous nodules
What is the predominant antibody in Specific Anti-Treponemal Antibodies?
IgM
When does IgG rapidly increase in Specific Anti-Treponemal Antibodies?
During the early stages of infection
What do Non-Treponemal Antibodies (Reagin Antibodies) indicate?
Other infectious diseases and conditions
What is the purpose of non-treponemal assays in serological testing for syphilis?
To screen for antibodies to cardiolipin released from damaged cells
Which type of antibody do the non-treponemal assays primarily target in serological testing?
IgG
What is the role of fluorescent-labeled antibody conjugate in the laboratory diagnosis of syphilis?
Detects specific T pallidum antibodies
Test your knowledge on specific anti-treponemal antibodies and non-treponemal antibodies in syphilis diagnosis. Learn about IgM and IgG antibodies, as well as their characteristics and clinical significance.
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