18 Questions
What is the first diagnostic blood test for syphilis?
Complement fixation test
What is the causative agent of syphilis?
Treponema pallidum
Which stage of syphilis is characterized by large sores inside the body or on the skin, cardiovascular syphilis, or neurosyphilis?
Tertiary stage
Which Treponema subspecies can cause yaws?
Treponema pallidum subsp. pertenue
What is the Gram stain characteristic of Treponema pallidum?
Gram-negative spirochete
What is the mode of transmission for congenital syphilis?
Congenital transmission
What type of antibodies are IgM antibodies in Treponemal serologic tests?
Predominantly produced early in infection
In Treponemal serologic tests, when does IgG antibody level rapidly increase?
At the end of the infection
What do non-Treponemal Antibodies (Reagin Antibodies) target in patients?
Components of their own cells
Why are non-Treponemal assays not specific for Treponema?
They detect antibodies to lipoprotein material and cardiolipin
What is the key to diagnosing syphilis in a patient without active lesions?
Serological testing for antibodies
What does a fluorescent-labeled antibody conjugate to Treponema pallidum indicate in testing methods?
Specific detection of T. pallidum antibodies
What is the primary stage symptom of Treponema pallidum subsp. endemicum?
Formation of a painless lesion at the site of entry
How can latent stage syphilis be described?
No symptoms are present
Which detection method is used for identifying rashes all over the body in syphilis?
Laboratory examination
What is the common name for Treponema pertenue, resembling syphilis with elevated granulomatous nodules?
Frambesia tropica
Which test is used for the detection of latent syphilis if untreated?
Non-treponemal tests for IgM and IgG
What does a patient experience when passing through the second stage of syphilis and then re-experiencing secondary stage symptoms?
Relapses of secondary stage symptoms
Test your knowledge on specific and non-specific antibodies produced in syphilis infections. Learn about the characteristics of IgM and IgG antibodies, as well as non-treponemal antibodies.
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