Neuro - Quiz 1

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Questions and Answers

Which of the following sensory modalities includes the perception of pain?

  • Proprioceptive sensations
  • Thermal sensations
  • Equilibrium
  • Somatic sensory modalities (correct)

What is the function of visceral senses?

  • They provide information about conditions within internal organs. (correct)
  • They detect external stimuli like light and sound.
  • They measure body temperature and pain.
  • They allow perception of joint movements.

Which sensory receptor process involves converting energy from a stimulus into a graded potential?

  • Sensory adaptation
  • Transmission of the signal
  • Stimulation of the sensory receptor
  • Transduction of the stimulus (correct)

Which type of sensation does NOT belong to the general senses?

<p>Hearing (D)</p> Signup and view all the answers

What allows proprioceptive sensations to provide information about body position and movement?

<p>Conscious and unconscious perception (C)</p> Signup and view all the answers

What characterizes an electrical synapse?

<p>The membranes of two cells are in tight contact to allow electrical coupling. (D)</p> Signup and view all the answers

Which of the following cells can serve as target cells in synaptic connections?

<p>Nerves, muscles, and glands (A)</p> Signup and view all the answers

How do electrical synapses compare to chemical synapses in terms of speed?

<p>They are faster than chemical synapses. (C)</p> Signup and view all the answers

What is the primary structural difference between chemical and electrical synapses?

<p>Chemical synapses have the presynaptic and postsynaptic cells separated by a gap. (D)</p> Signup and view all the answers

Which statement about synapses is correct?

<p>Chemical synapses allow for complex signaling due to the presence of a synaptic cleft. (B)</p> Signup and view all the answers

What type of sensory receptor adapts slowly to a stimulus and continues to transmit signals?

<p>Tonic receptors (A), Proprioceptors (B)</p> Signup and view all the answers

Which of the following statements accurately describes phasic receptors?

<p>They rapidly adapt and mainly signal changes in the stimulus. (A)</p> Signup and view all the answers

What happens to sensory receptors during adaptation?

<p>Their responsiveness typically diminishes while the stimulus is maintained. (B)</p> Signup and view all the answers

Which receptor type is known for not adapting to stimuli?

<p>Nociceptors (B)</p> Signup and view all the answers

Which of the following examples correctly illustrates rapid adaptation in sensory receptors?

<p>Realizing a bad smell disappears over time (C)</p> Signup and view all the answers

What type of sensory neurons carry impulses from the peripheral nervous system into the central nervous system?

<p>First order neurons (B)</p> Signup and view all the answers

Which type of receptor is primarily responsible for detecting mechanical stress such as pressure and vibration?

<p>Mechanoreceptors (C)</p> Signup and view all the answers

What happens when graded potentials in sensory neurons reach the threshold level?

<p>They generate impulses (B)</p> Signup and view all the answers

Which type of receptors lack structural specialization and are responsible for detecting pain and temperature?

<p>Free nerve endings (C)</p> Signup and view all the answers

Which statement regarding the integration of sensory input is correct?

<p>Conscious sensations are integrated in the cerebral cortex. (D)</p> Signup and view all the answers

What is the primary role of nociceptors in the human body?

<p>To detect potential damage to tissues (C)</p> Signup and view all the answers

What type of receptors are responsible for detecting light and are found in the retina?

<p>Photoreceptors (D)</p> Signup and view all the answers

What phenomenon occurs when initial pain stimuli lead to increased sensitivity to further painful stimuli?

<p>Hyperalgesia (D)</p> Signup and view all the answers

Which type of response illustrates the inhibition of pain transmission through descending pathways?

<p>Stimulation-produced analgesia (A)</p> Signup and view all the answers

Which receptor type detects changes in temperature and has two distinct types for hot and cold stimuli?

<p>Thermoreceptors (D)</p> Signup and view all the answers

Which classification of receptors responds primarily to external stimuli like touch and temperature?

<p>Exteroceptors (B)</p> Signup and view all the answers

What characterizes encapsulated nerve endings compared to free nerve endings?

<p>They have specialized connective tissue capsules. (C)</p> Signup and view all the answers

What type of sensory receptor is responsible for responding to electromagnetic waves?

<p>Electromagnetic receptors (A)</p> Signup and view all the answers

What type of neurotransmitter is classified as an endorphin?

<p>Neuropeptide (C)</p> Signup and view all the answers

Which receptor does morphine primarily act on?

<p>Opiate receptors (D)</p> Signup and view all the answers

How does cocaine affect dopamine in the synaptic cleft?

<p>Blocks the reuptake system (A)</p> Signup and view all the answers

What is the primary effect of nerve gas (Sarin) on neurotransmission?

<p>Blocks acetylcholine removal (C)</p> Signup and view all the answers

What autoimmune condition is characterized by antibodies that antagonistically affect acetylcholine receptors?

<p>Myasthenia Gravis (B)</p> Signup and view all the answers

Which component is NOT considered a basic constituent of neural circuits?

<p>Muscle fibers (A)</p> Signup and view all the answers

What type of neurotransmission is primarily implicated in epilepsy?

<p>Reduced inhibitory transmission (B)</p> Signup and view all the answers

What structure provides the primary location for synaptic connectivity?

<p>Neuropil (C)</p> Signup and view all the answers

Which of the following is an example of a neuronal pool?

<p>A group of connected interneurons (C)</p> Signup and view all the answers

In the myotatic reflex, sensory neurons transmit information in which direction?

<p>Toward the central nervous system (D)</p> Signup and view all the answers

Which psychiatric condition is linked with low levels of serotonin?

<p>Depression (D)</p> Signup and view all the answers

What term describes neurons that only participate in local aspects of a circuit?

<p>Interneurons (A)</p> Signup and view all the answers

What is the effect of cold on endorphin levels?

<p>Increases endorphin levels (C)</p> Signup and view all the answers

What is one function of endorphins?

<p>Reduce stress (D)</p> Signup and view all the answers

What is the primary role of neurotransmitters at synapses?

<p>To facilitate the transmission of action potentials (D)</p> Signup and view all the answers

What determines the amplitude of an excitatory postsynaptic potential (EPSP)?

<p>The number of vesicles released from the presynaptic cell (C)</p> Signup and view all the answers

How do inhibitory neurotransmitters affect the postsynaptic cell?

<p>They lead to hyperpolarization of the cell (C)</p> Signup and view all the answers

What is the primary excitatory neurotransmitter in the central nervous system (CNS)?

<p>Glutamate (D)</p> Signup and view all the answers

What enzyme is responsible for degrading serotonin in the synaptic cleft?

<p>Monoamine oxidase (MAO) (D)</p> Signup and view all the answers

Which neurotransmitter is primarily involved in muscle contraction?

<p>Acetylcholine (C)</p> Signup and view all the answers

What happens to the membrane potential when excitatory neurotransmitters bind to their receptors?

<p>The membrane potential becomes more positive (B)</p> Signup and view all the answers

Which of the following is NOT an example of an inhibitory neurotransmitter?

<p>Acetylcholine (D)</p> Signup and view all the answers

How do modulating neurotransmitters differ from fast-acting neurotransmitters?

<p>They act more slowly and have longer-lasting effects (D)</p> Signup and view all the answers

Which neurotransmitter is synthesized from the amino acid tryptophan?

<p>Serotonin (D)</p> Signup and view all the answers

What is the function of the receptor channels in nerve synapses?

<p>To facilitate ion movement across the membrane (B)</p> Signup and view all the answers

What role does vitamin B6 play in serotonin production?

<p>It helps synthesize serotonin (B)</p> Signup and view all the answers

Which of the following neurotransmitters can act both as a neurotransmitter and a modulator?

<p>Serotonin (C)</p> Signup and view all the answers

How is the action potential concluded at the presynaptic cell?

<p>By degradation of the neurotransmitter (D)</p> Signup and view all the answers

What is divergence in neuronal pools?

<p>The spread of information from one pool to multiple pools (D)</p> Signup and view all the answers

How does convergence affect motor neurons?

<p>It allows conscious control over the same motor neurons (A)</p> Signup and view all the answers

What characterizes serial processing in neurons?

<p>Information is relayed in a stepwise fashion from one pool to another (B)</p> Signup and view all the answers

What does parallel processing allow in the context of sensory information?

<p>Simultaneous processing of information by several neuronal pools (D)</p> Signup and view all the answers

What is reverberation in a neural circuit?

<p>A feedback loop that continues to stimulate itself (B)</p> Signup and view all the answers

Which of the following best defines sensation?

<p>Any stimulus the body is aware of through its receptors (C)</p> Signup and view all the answers

What distinguishes perception from sensation?

<p>Perception involves the storage of sensory memories in the cortex (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of divergence?

<p>Restricting the information to a few options (C)</p> Signup and view all the answers

What can occur when sensory impulses reach the spinal cord?

<p>Only simple reflex actions like the stretch reflex (B)</p> Signup and view all the answers

Which pattern of interaction among neurons allows for the same inputs to produce different outputs?

<p>Convergence (D)</p> Signup and view all the answers

In which situation is serial processing primarily observed?

<p>When relaying information between different hemispheres of the brain (A)</p> Signup and view all the answers

What type of feedback is involved in maintaining normal breathing according to reverberation?

<p>Negative feedback (C)</p> Signup and view all the answers

What is NOT a sensory modality?

<p>X-rays (C)</p> Signup and view all the answers

What mechanism allows a sharp stimulus to produce multiple simultaneous reactions?

<p>Divergence (B)</p> Signup and view all the answers

Which of the following best describes the relationship between sensation and perception?

<p>Sensation is the physical input; perception is the interpretation of that input (C)</p> Signup and view all the answers

Flashcards

Synapse

The point where a nerve cell (neuron) communicates with another cell.

What does a synapse connect to?

Nerve cells, muscle cells, or glands.

Electrical Synapse

A type of synapse where the membranes of two cells are tightly connected, allowing nerve impulses to pass quickly and reliably.

Chemical Synapse

A type of synapse where the cells are separated by a small gap called the synaptic cleft, and communication happens through chemical messengers.

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What is special about electrical synapses vs. chemical synapses?

A type of synapse where the cells are directly touching each other, resulting in faster and more synchronized communication.

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Sensation

The ability to detect changes in the environment through sensory receptors.

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Sensory Receptors

Specialized cells or dendrites of sensory neurons that respond to specific stimuli.

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Transduction

The conversion of a stimulus into a graded potential by a sensory receptor.

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Somatic Senses

Sensations that arise from the skin, muscles, joints, and tendons, providing information about touch, pressure, temperature, pain, and body position.

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Visceral Senses

Sensations that arise from internal organs, providing information about conditions like fullness, pain, and pressure.

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Proprioceptors

A type of sensory receptor found in muscles, tendons, and joint capsules. They provide information about body position and movement.

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Adaptation

The tendency of sensory receptors to decrease their response to a constant stimulus over time.

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Tonic Receptor

A type of sensory receptor that adapts slowly to a stimulus and continues to signal for the duration of the stimulus. It provides information about the duration of the stimulus.

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Phasic Receptor

A type of sensory receptor that adapts rapidly to a stimulus. It does not provide information about the duration of the stimulus, but rather responds to changes in stimulus intensity or rate.

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Rapidly Adapting Receptors

Sensory receptors that are specialized for detecting changes in stimuli, such as smell, pressure, and touch.

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Synaptic Transmission

The process by which a chemical neurotransmitter is released from the presynaptic cell, allowing for the transmission of signals across a synapse.

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Neurotransmitter Release Regulation

The ability of a presynaptic neuron to control the amount of neurotransmitter released, ensuring precise signal transmission.

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Neurotransmitter

A specific molecule released from the presynaptic neuron that binds to receptors on the postsynaptic neuron, triggering changes in its activity.

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Neurotransmitter Receptor

The specific protein on the postsynaptic neuron that binds to a neurotransmitter, initiating a response.

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Ionotropic Receptor

A type of receptor that can act as both a binding site for a neurotransmitter and an ion channel, allowing for direct ion flow.

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Receptor Activation

The change in the three-dimensional structure of a receptor upon neurotransmitter binding, resulting in the opening of an ion channel.

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Excitatory Post-Synaptic Potential (EPSP)

A localized depolarization of the postsynaptic membrane, making it more likely to generate an action potential. Caused by the influx of positively charged ions.

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Inhibitory Post-Synaptic Potential (IPSP)

A localized hyperpolarization of the postsynaptic membrane, making it less likely to generate an action potential. Caused by the influx of negatively charged ions.

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Glutamate

The main excitatory neurotransmitter in the central nervous system (CNS). Involved in learning and memory.

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Acetylcholine

The neurotransmitter at nerve-skeletal muscle synapses, triggering muscle contraction.

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Glycine

A neurotransmitter that inhibits postsynaptic activity, often by increasing chloride permeability, making the cell more negative.

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Gamma Aminobutyric Acid (GABA)

The primary inhibitory neurotransmitter in the brain, involved in regulating anxiety, sleep, and motor control.

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Serotonin (5-HT)

A neurotransmitter involved in mood regulation, sleep, appetite, and other functions. Made from tryptophan.

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Monoamine Oxidase (MAO)

An enzyme that breaks down serotonin in the synaptic cleft, terminating its action.

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Modulator (e.g., Serotonin, Dopamine)

A type of neurotransmitter that can have long-lasting, modulating effects on the postsynaptic cell, potentially influencing gene expression.

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What are endorphins?

Endorphins are neuropeptides that act as natural painkillers, reduce stress, and promote calmness.

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How do endorphins work?

Endorphins inhibit pain signals by binding to opioid receptors in the brain and spinal cord.

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What increases endorphin levels?

Activities like exercise and exposure to cold can increase endorphin production, leading to feelings of euphoria and pain relief.

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How does nicotine affect the brain?

Nicotine activates nicotinic acetylcholine receptors, primarily in the brain, which causes the release of dopamine, leading to feelings of euphoria.

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How does curare work?

Curare, a South American arrow poison, blocks acetylcholine receptors, preventing muscle contraction and resulting in flaccid paralysis.

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What are the effects of morphine and heroin?

Morphine and heroin act on opiate receptors, producing pain relief, euphoria, and sedation.

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How does cannabis affect the brain?

Cannabis affects the brain by activating cannabinoid receptors, leading to a range of effects including relaxation, altered perception, and appetite increase.

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How does cocaine work?

Cocaine blocks the reuptake of dopamine, causing an increase in dopamine levels in the synaptic cleft. This excess dopamine leads to feelings of euphoria and increased alertness.

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How does sarin work?

Saringas works by blocking the removal of acetylcholine at nerve-muscle synapses, leading to continuous muscle contraction and spastic paralysis.

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What is Myasthenia Gravis?

Myasthenia Gravis is an autoimmune disorder where antibodies block acetylcholine receptors at the neuromuscular junction, leading to muscle weakness and fatigue.

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What is Graves' disease?

Graves' disease is an autoimmune disorder where antibodies stimulate the thyroid gland, leading to an overproduction of thyroid hormones.

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How is epilepsy linked to synapses?

Epilepsy is often linked to reduced inhibitory neurotransmission of GABA in the brain, resulting in excessive neuronal activity and seizures.

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How are depression and schizophrenia related to synapses?

Depression and schizophrenia are often linked to dysfunctions in synaptic transmission involving neurotransmitters like serotonin and dopamine.

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What are neuronal pools?

Neuronal pools are groups of interconnected neurons with specific functions, playing a crucial role in processing information in the nervous system.

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What is a neuropil?

A neuropil is a tangled network of dendrites, axon terminals, and glial cells where most synaptic connections occur.

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Neuronal pool

A group of interconnected neurons that work together to perform a specific function within the nervous system.

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Neural circuit

The pattern of communication between neurons within a circuit.

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Divergence

The spread of information from one neuronal pool to multiple other pools, enabling broad distribution of a signal.

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Convergence

The convergence of multiple neurons onto a single postsynaptic neuron, allowing for integrated input.

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Serial processing

A step-by-step relay of information from one neuronal pool to another, often used for transmitting sensory signals.

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Parallel processing

The simultaneous processing of the same information by multiple neurons or pools, allowing for parallel responses.

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Reverberating circuit

A neural circuit that utilizes feedback to sustain or amplify its own activity, often involved in maintaining consciousness or rhythmic processes.

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Perception

The conscious interpretation and understanding of sensations, providing meaning and context.

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Sensory modality

The distinct quality or type of sensation, such as sight, sound, taste, touch, or smell.

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Spinal reflex

A reflex that involves the spinal cord only, without requiring input from the brain.

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Brain stem reflex

A reflex that involves the brain stem, controlling basic physiological functions like heart rate and breathing.

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Cerebral cortex sensation

A sensation that reaches the cerebral cortex, allowing for detailed and conscious processing of the stimulus.

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Sensory transduction

The process of converting a sensory stimulus into a neural signal that the brain can understand.

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Olfactory Receptor Signal Transduction

Stimulation of olfactory receptors in the nose results in conversion of chemical energy to electrical signals in the form of graded potentials.

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Graded Potentials

Graded potentials vary in strength depending on the intensity of the stimulus. Unlike action potentials, they are not propagated.

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First Order Neurons (1Ëš)

Sensory neurons that transmit signals from the peripheral nervous system (PNS) to the central nervous system (CNS).

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Sensory Integration by the CNS

The process of receiving and integrating sensory information within the central nervous system.

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Free Nerve Endings

Free nerve endings are unmyelinated dendrites that lack structural specialization and respond to pain, temperature, tickle, itch, and light touch.

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Encapsulated Nerve Endings

Encapsulated nerve endings are dendrites enclosed in connective tissue capsules that respond to pressure, vibration, and deep touch.

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Separate Sensory Cells

Separate sensory cells are specialized for specific senses (like vision, taste, hearing, and balance) and synapse with first-order neurons.

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Mechanoreceptors

Mechanoreceptors respond to physical or mechanical stress, such as touch, pressure, vibration, hearing, proprioception, and equilibrium.

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Thermoreceptors

Thermoreceptors are sensitive to changes in temperature, with specialized receptors for both heat and cold.

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Nociceptors

Nociceptors detect potential tissue damage by responding to intense mechanical deformation, excessive heat, or chemical signals.

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Chemoreceptors

Chemoreceptors respond to chemicals such as those involved in taste and smell, as well as blood oxygen, CO2, glucose, and pH.

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Photoreceptors

Photoreceptors detect visible light. Rods are highly sensitive but do not distinguish color, while cones are less sensitive but detect different colors.

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Generator Potential

A type of graded potential produced by free nerve endings, encapsulated nerve endings, and olfactory receptors. When large enough, it triggers a nerve impulse in a first-order neuron.

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Receptor Potential

A type of graded potential produced by receptors involved in vision, hearing, equilibrium, and taste. It triggers the release of neurotransmitters, which in turn can generate a nerve impulse in a first-order neuron.

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Exteroceptors

Exteroceptors are located near the surface of the body and receive external stimuli, such as touch, pressure, pain, temperature, hearing, vision, smell, and taste.

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Study Notes

Synapses

  • Synapses are specialized junctions where neurons communicate with target cells.
  • Target cells include nerves, muscles, and glands.
  • Two types of synapses: electrical and chemical.

Electrical Synapses

  • Rare in vertebrates.
  • Membranes of the two cells are in close contact, creating electrical coupling.
  • Enables fast and reliable transmission of nerve impulses (action potentials).
  • Faster than chemical synapses.
  • More synchronized.

Chemical Synapses

  • More common.
  • Presynaptic and postsynaptic cells are separated by a synaptic cleft (10-15 times wider than electrical synapses).
  • Transmission relies on neurotransmitters released from the presynaptic cell.
  • Allows for precise control of neurotransmitter release.

Neurotransmitters

  • Neurotransmitters and their receptors have a lock-and-key fit.
  • At nerve-muscle and many nerve-nerve synapses, receptors act as ion channels.
  • Binding of a neurotransmitter changes the receptor shape, opening an intrinsic pore.

Excitatory Postsynaptic Potentials (EPSPs)

  • Excitatory neurotransmitters open ion channels allowing positively charged sodium ions to enter the cell.
  • This depolarizes the postsynaptic membrane, creating an EPSP.
  • EPSP amplitude is roughly proportional to the number of released vesicles.
  • Sufficiently large EPSPs trigger an action potential in the target cell.

Inhibitory Transmitters

  • Inhibitory neurotransmitters make the postsynaptic cell less excitable.
  • Often associated with chloride or potassium channels, leading to hyperpolarization (making the interior more negative).
  • Examples include glycine and GABA.

Acetylcholine and Glutamate

  • Acetylcholine is excitatory at nerve-skeletal muscle synapses.
  • Glutamate is the main excitatory neurotransmitter in the central nervous system.

Serotonin (5-hydroxytryptamine, 5-HT)

  • Synthesized from tryptophan, with vitamin B6 aiding the process.
  • Predominantly found in the gut.
  • Stored in vesicles in the presynaptic terminals.
  • Action potential triggers exocytosis of serotonin into the synaptic cleft.
  • Serotonin binds to receptors on the postsynaptic cell, depolarizing it.
  • Reaching threshold initiates an action potential in the postsynaptic cell.
  • Remaining serotonin is degraded by monoamine oxidase (MAO).
  • MAO also degrades reabsorbed serotonin, terminating nerve signals and preparing the synapse for subsequent impulses.
  • Catechol-O-methyl transferase (COMT) targets catecholamines (not serotonin).
  • MAOIs are antidepressants.
  • Serotonin can act as a modulator.

Modulation

  • Slower and longer-lasting than fast neurotransmitters.
  • Often involve activation of intracellular messengers (not directly opening ion channels).
  • Can affect gene expression.
  • Multiple neurotransmitters/modulators can be released by a single nerve terminal.

Enkephalins (Opiates/Endorphins)

  • Neuropeptide.
  • Inhibitory effect.
  • Located in the brain and spinal cord.
  • Functions: stress reduction, promoting calmness, natural pain killer.
  • Cold and exercise likely increase endorphin production.

Synapse Abuse

  • Many drugs affect synapses.
  • Nicotine activates nicotinic acetylcholine receptors, causing dopamine release.
  • Curare is an antagonist of acetylcholine receptors, blocking neuromuscular transmission.
  • Morphine/Heroin act on opiate receptors.
  • Cannabis acts on cannabinoid receptors.
  • Cocaine blocks dopamine reuptake (prolonged dopamine in the cleft).
  • Nerve gas (Sarin) blocks acetylcholine removal, causing spastic paralysis.

Disorders of Synaptic Function

  • Myasthenia Gravis: Autoantibodies antagonize acetylcholine receptors, leading to reduced neurotransmission and fatigue.
  • Graves Disease: Autoantibodies agonistically bind to the thyroid gland.
  • Epilepsy: Possibly linked to decreased inhibitory transmission (GABA).
  • Depression/Schizophrenia: Likely involve serotonin/dopamine synapse disruptions.

Neural Circuits

  • Neurons function in ensembles.
  • Synaptic connections form a neuropil, a dense network between cell bodies, where most connections occur.
  • Afferent neurons carry information to the CNS.
  • Efferent neurons carry information away from the CNS.
  • Interneurons participate in local circuits.
  • Example: stretch reflex circuit (sensory afferents, interneurons, motor efferents).

Neuronal Pools

  • Groups of interconnected neurons with specific functions.
  • Defined functionally, not anatomically.
  • Five circuit patterns: divergence, convergence, serial processing, parallel processing, reverberation.

Sensation

  • Conscious/unconscious awareness of stimuli.
  • Nature of sensation depends on impulse destination and receptor type.
  • Can range from simple reflexes to complex perceptions.

Sensation vs. Perception

  • Sensation: Awareness of any stimulus detected by receptors.
  • Perception: Conscious awareness and interpretation of a sensation.

Sensory Modality

  • Property differentiating one sensation from another.
  • General senses (somatic & visceral) and special senses (smell, taste, vision, hearing, equilibrium).

General Senses

  • Somatic senses: tactile (touch, pressure, vibration, itch), thermal (temperature), pain, proprioceptive (joint/muscle position).
  • Visceral senses: Conditions within internal organs (e.g., pressure, pain).

Special Senses

  • Smell, taste, vision, hearing, equilibrium (cranial nerves).

Process of Sensation

  • 4 steps: stimulation of sensory receptor, transduction into a graded potential (generator or receptor potential), generation of impulses (action potentials), and integration by the CNS.

Sensory Receptors

  • Range from simple to complex structures.
  • Classified by structure, stimulus type, response to stimulus, and location.

Types of Receptors

  • Free nerve endings: Bare dendrites (pain, temperature, itch, light touch).
  • Encapsulated nerve endings: Dendrites in connective tissue capsules (pressure, vibration, deep touch).
  • Separate sensory cells: Specialized cells that synapse onto neurons (vision, taste, hearing, equilibrium - except smell).

Stimulus Types of Receptors

  • Mechanoreceptors: Detect physical or mechanical stress.
  • Thermoreceptors: Detect temperature changes (hot/cold).
  • Nociceptors: Detect potential tissue damage (intense mechanical deformation, excessive heat, chemicals).
  • Chemoreceptors: Detect chemicals (taste, smell, blood oxygen, pH).
  • Photoreceptors: Detect light (rods/cones).
  • Other: Electromagnetic receptors, baroreceptors.

Hyperalgesia/Stimulation-produced analgesia

  • Hyperalgesia: Increased sensitivity to pain after initial stimulus.
  • Stimulation-produced analgesia: Descending pathways inhibiting pain signals; opioids involved.
  • Referred pain: Pain felt at site different from actual injury location.

Pain-Gate Theory

  • Stimulation of non-pain afferents can inhibit pain pathways (TENS).

Receptor Potential

  • A graded potential in receptors in the special senses.

Receptor Location

  • Exteroceptors: External stimuli.
  • Interoceptors: Internal stimuli (e.g., blood pressure).
  • Proprioceptors: Body position (muscles, tendons, joints).

Adaptation

  • Most receptors adapt (decrease sensitivity to maintained stimuli).
  • Tonic receptors: Adapt slowly, provide information about stimulus duration.
  • Phasic receptors: Adapt rapidly, signal changes in stimulus intensity.

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