Symptoms of Cholestasis and Their Effects
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Questions and Answers

What is a specific mechanism by which the kidney adapts to support bile salt removal from the blood in cholestasis?

  • Decreasing tubular reabsorption of bile acids
  • Decreasing tubular secretion of bile
  • Decreasing glomerular filtration
  • Increasing active secretion of bile (correct)
  • Which specific protein, mentioned in the text, increases its expression in the kidney to aid in renal bile salt and toxin elimination?

  • MRP2 (correct)
  • Albumin
  • Insulin
  • Glucagon
  • What clinical manifestation is suggested by gastrointestinal symptoms such as prolonged right upper quadrant pain or tenderness, epigastric tenderness, and stool changes indicating fat malabsorption?

  • Cirrhosis
  • Biliary obstruction (correct)
  • Cholecystitis
  • Primary biliary cholangitis
  • Which condition among the following may lead to cholestasis as mentioned in the text?

    <p>Primary sclerosing cholangitis</p> Signup and view all the answers

    What kind of cholestasis is specifically suggested by symptoms like discomfort or nausea after meals and evidence of gross fat malabsorption?

    <p>Primary biliary cholangitis-related cholestasis</p> Signup and view all the answers

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