30 Questions
What neurotransmitter dysfunctions are associated with symptoms of increased negative affect?
Serotonin (5HT) and norepinephrine (NE) dysfunction
What is required when prescribing mood-stabilizing drugs?
All of the above
Which medication should be taken with at least 350 calories of food for maximum absorption and may be used as a second-line treatment for new-onset bipolar disorder in women who do not want to wait for long-term contraception or decide to get pregnant?
Lurasidone
For patients with renal failure who are prescribed lithium carbonate (Lithobid), what is the recommended starting dose adjustment?
The starting dose should be reduced by at least 50%
Which drug classes can increase lithium levels?
NSAIDs and ACE inhibitors
Which substance is mentioned in the text as decreasing lithium levels?
Caffeine
Which labs should be monitored for a patient on lithium?
Serum lithium level, renal function, and thyroid function
When does a patient need to return for lithium serum level monitoring after a dose increase?
The text does not specify a timeframe
What symptoms are associated with increased negative affect due to 5HT and NE dysfunction?
Depressed mood, guilt, fear, anxiety
What is a requirement for all antidepressants as per the FDA?
Information about potential risks of mania on product labeling
Which drug class may be used as a second-line treatment for new-onset bipolar disorder in women who do not want to wait for long-term contraception or decide to get pregnant?
Lurasidone
What is the recommended starting dose adjustment for patients with renal failure who are prescribed lithium carbonate?
Reduce the dose by at least 50%
Which two drug classes can increase lithium levels?
NSAIDs and ACE inhibitors
Which labs should be monitored for a patient on lithium?
Serum lithium level, renal function, and thyroid function
When should a patient return for lithium serum level monitoring after an increase in their lithium dose?
$1-2$ days after the dose increase
What is a common side effect of mood-stabilizing drugs that may require routine laboratory monitoring?
Nephrotoxicity
What are the symptoms associated with increased negative affect due to 5HT and NE dysfunction?
Depressed mood, guilt, fear, anxiety, hostility, irritability, loneliness, appetite changes
What is the starting dose requirement for patients with renal failure who are prescribed lithium carbonate (Lithobid)?
The starting dose should be reduced by at least 50%
Which two drug classes can increase lithium levels?
NSAIDs and ACE inhibitors
What medication should be taken with at least 350 calories of food for maximum absorption and may be used as a second-line treatment for new-onset bipolar disorder in women who do not want to wait for long-term contraception or decide to get pregnant?
Lurasidone
What is required when prescribing mood-stabilizing drugs?
Both b and c
What is the FDA requirement for all antidepressants?
Product labeling must contain information about potential risks of mania
Which substance is mentioned in the text as decreasing lithium levels?
Caffeine
When does a patient need to return for lithium serum level monitoring after an increase in their lithium dose?
After 2 weeks
Which laboratory tests should be monitored for a patient taking valproic acid (Depakote)?
Serum valproate level, liver function, and CBC
When should lithium serum levels be monitored after a dose adjustment?
5 days after the adjustment
Which laboratory tests should be monitored for a patient taking carbamazepine?
Serum carbamazepine levels, renal and liver function, and CBC
What is the recommended frequency for monitoring lithium levels in a stable patient?
Every 6 months
Which laboratory tests should be monitored for patients taking atypical antipsychotics?
CBC and HbA1c
What is a requirement when prescribing mood-stabilizing drugs to women of childbearing age?
Pre-conception and contraceptive counseling
This quiz covers symptoms of increased negative affect like depressed mood, guilt, anxiety, as well as the prescribing pearls for mood stabilizing drugs such as baseline monitoring and contraceptive counseling. Test your knowledge on mood-related symptoms and regulatory requirements when prescribing drugs.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
