Pharmaceutical Science Quiz

Pharmacodynamics vs Pharmacokinetics

• Pharmacodynamics studies the effects of drugs on the body, including mechanisms of action and the relationship between drug concentration and effect.
• Pharmacokinetics investigates the movement of drugs within the body, focusing on absorption, distribution, metabolism, and excretion (ADME).

Phase I Metabolism

• The primary focus of phase I metabolism is to modify drugs through chemical alterations, such as oxidation, reduction, or hydrolysis, to enhance their excretion.
• Phase I reactions typically involve cytochrome P450 enzymes that facilitate the biochemical transformation of drugs.

Elimination Routes

• Routes of elimination include urine, feces, sweat, breath, and lactation. These pathways are vital for the clearance of drugs and their metabolites from the body.

Focus Areas of Pharmacokinetics and Pharmacodynamics

• The main focus of pharmacokinetics is to understand how the body affects a drug over time, including the processes of absorption, distribution, metabolism, and excretion.
• The primary focus of pharmacodynamics is to determine how a drug produces its effects at the target sites within the body.

Key Terms in Pharmacology

• ADME stands for Absorption, Distribution, Metabolism, and Excretion, representing the four key processes that affect drug availability and action.
• Enterohepatic circulation refers to the recycling of drugs and metabolites between the liver and the intestines, which can influence the duration and effectiveness of drug action.

Test your knowledge of pharmacology, pharmaceutical chemistry, and pharmacy practice with this quiz. Learn about ADME, pharmacodynamics, pharmacokinetics, routes of administration, absorption, distribution, and metabolism. Presented by Dr. Rajan, this quiz will help you understand essential concepts in pharmaceutical science.