Surgical Oncology Concepts
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Questions and Answers

Which virus is associated with cervical cancer and preventable by vaccination?

  • Helicobacter pylori
  • Hepatitis B virus
  • Schistosoma japonicum
  • Human papilloma virus (HPV) (correct)
  • Cancer causes more deaths than AIDS, tuberculosis, and malaria combined.

    True

    Name the study that focuses on the incidence and distribution of disease.

    Epidemiology

    A neoplasm that has the potential to progress to cancer if left untreated is called a ______.

    <p>pre-malignancy</p> Signup and view all the answers

    Match the biological agents with their associated locations or conditions:

    <p>Hepatitis B virus = Liver Schistosoma japonicum = Gut, bladder Helicobacter pylori = Stomach Human papilloma virus (HPV) = Cervical cancer</p> Signup and view all the answers

    Which of the following is NOT a form of cancer screening?

    <p>Biopsy</p> Signup and view all the answers

    Granulomas are used by parasites to help transport eggs into the gut.

    <p>True</p> Signup and view all the answers

    What term describes a solid neoplasm that is not invasive?

    <p>Tumour</p> Signup and view all the answers

    What is the purpose of surgical margins in cancer treatment?

    <p>To determine if the entire tumour was removed</p> Signup and view all the answers

    A tumour can never recur after surgical excision.

    <p>False</p> Signup and view all the answers

    What is meant by the term 'metastasis'?

    <p>New tumours that appear far from the original tumour.</p> Signup and view all the answers

    The probability of survival five years after diagnosis is known as _____ .

    <p>prognosis</p> Signup and view all the answers

    Which mode of chemotherapy is used before surgical removal to shrink the tumour?

    <p>Neoadjuvant chemotherapy</p> Signup and view all the answers

    Match the following chemotherapy types with their descriptions:

    <p>Primary chemotherapy = Used as the sole anti-cancer treatment Concurrent chemotherapy = Given simultaneously with radiation Adjuvant chemotherapy = Given after surgical removal of the tumour Neoadjuvant chemotherapy = Given before surgery to shrink the tumour</p> Signup and view all the answers

    What grading system is commonly used to assess cervical intraepithelial neoplasia?

    <p>Bethesda</p> Signup and view all the answers

    Chemotherapy is a treatment method that uses radiation to kill cancer cells.

    <p>False</p> Signup and view all the answers

    Which of the following is not a characteristic of malignant neoplasms?

    <p>Self-limited</p> Signup and view all the answers

    Cigarette tobacco is associated with the development of cancer in several areas including the lung and bladder.

    <p>True</p> Signup and view all the answers

    What is the branch of medicine that studies, diagnoses, treats, and prevents cancer called?

    <p>Oncology</p> Signup and view all the answers

    Malignant neoplasms can spread to other locations in the body through the _____ or lymphatic system.

    <p>blood</p> Signup and view all the answers

    Which of the following factors is associated with breast, vaginal, and endometrial carcinomas?

    <p>Oestrogens</p> Signup and view all the answers

    Match the following carcinogenic substances with the types of cancer they are associated with:

    <p>Asbestos = Lung cancer Vinyl chloride = Liver (angiosarcoma) Aflatoxin = Liver cancer Polycyclic hydrocarbons = Skin cancer</p> Signup and view all the answers

    Benign neoplasms do not invade surrounding tissues or metastasize.

    <p>True</p> Signup and view all the answers

    Name one biological agent that can contribute to the development of cancer.

    <p>Infectious agents</p> Signup and view all the answers

    Study Notes

    Surgical Procedures and Recurrence

    • Surgical excision involves the removal of a tumor by a surgeon to prevent further growth.
    • Recurrence refers to the appearance of a new tumor at the original site post-surgery.
    • Surgical margins are assessed by a pathologist to determine if the tumor was fully excised (negative margins) or if remnants remain (positive margins).

    Grading and Staging of Tumors

    • Tumor grading, typically on a scale of 3, reflects how similar the tumor is to surrounding healthy tissue.
    • Grading systems include Bethesda and Gleeson.
    • Tumor staging, commonly on a scale of 4, indicates the degree of invasion within the body.
    • Metastasis is the development of new tumors away from the primary site.
    • Transformation refers to the progression of a low-grade tumor into a higher-grade malignancy.
    • Prognosis estimates the likelihood of successful treatment, usually expressible as a five-year survival rate post-diagnosis.

    Chemotherapy Basics

    • Primary chemotherapy serves as the sole treatment, especially effective for highly sensitive tumors.
    • Concurrent chemotherapy is administered alongside radiation to enhance cancer cell vulnerability.
    • Adjuvant chemotherapy follows surgical removal to eliminate microscopic residual cancer.
    • Neoadjuvant chemotherapy is given before surgery to reduce tumor size for improved surgical outcomes.

    Tumor Classification and Associated Risks

    • Carcinomas arise from epithelial cells and are categorized as malignant tumors.
    • Infectious agents associated with cancer include:
      • Hepatitis B virus linked to liver cancer.
      • Schistosoma japonicum, a parasite affecting gut and bladder.
      • Helicobacter pylori, a bacterium associated with stomach cancer.
      • Human papilloma virus (HPV), preventable by the Gardasil vaccine, linked to cervical cancer.

    Epidemiology and Impact

    • Epidemiology examines disease incidence and distribution, projecting 17 million cancer deaths by 2030, accounting for 13% of global deaths.
    • Cancer ranks as a leading cause of death globally, surpassing deaths from AIDS, tuberculosis, and malaria combined.

    Tumors and Early Detection

    • Tumors, defined as solid neoplasms, can be pre-malignant, having potential for progression to cancer without intervention.
    • Pre-malignant conditions include atypia, dysplasia, and carcinoma in situ.
    • Screening tests, such as mammograms, detect tumors in asymptomatic individuals.
    • A definitive diagnosis requires biopsy and pathologist evaluation.

    Cancer Definition and Characteristics

    • Neoplasm indicates new growth, while malignant neoplasms show uncontrolled growth, invasion of adjacent tissues, and the potential to metastasize.
    • Benign neoplasms are characterized by self-limiting growth without invasion or metastasis.
    • Oncology focuses on cancer study, diagnosis, treatment, and prevention.

    Aetiology and Contributing Factors

    • Cancer causes are often elusive, but notable risk factors include tobacco, alcohol, diet, UV light exposure, infectious pathogens, and certain drugs.
    • Specific causative agents associated with cancer include:
      • Smoking linked to mouth, lung, and bladder cancers.
      • UV exposure correlating with skin cancers.
      • Asbestos exposure primarily linked to lung cancer.
      • Oestrogen, a risk factor for breast and reproductive cancers.

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    Description

    Test your knowledge on key surgical oncology terms such as surgical excision, recurrence, and surgical margins. This quiz covers the essential definitions and significance of tumor removal techniques and pathology grading. Challenge yourself to see how well you understand these crucial concepts in cancer treatment.

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