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Questions and Answers
What is the common chemical nucleus of sulfonamides?
What is the common chemical nucleus of sulfonamides?
- Resembling thiazide diuretics
- Resembling P amino benzoic acid (PABA) (correct)
- Resembling bilirubin
- Resembling folic acid
What is the pharmacokinetic feature of sulfonamides?
What is the pharmacokinetic feature of sulfonamides?
- Renal metabolism
- Extensive tissue penetration
- Excretion in feces
- Modest tissue penetration (correct)
How do sulfonamides affect the solubility in acidic urine?
How do sulfonamides affect the solubility in acidic urine?
- Become more soluble in acidic urine
- Remain unaffected by urine pH
- May be decreased, resulting in precipitation of metabolites (correct)
- May be increased, leading to crystallization
What is the selective toxicity of sulfonamides attributed to?
What is the selective toxicity of sulfonamides attributed to?
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What type of organisms are sulfonamides active against?
What type of organisms are sulfonamides active against?
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What route of administration is indicated for simple urinary tract infections?
What route of administration is indicated for simple urinary tract infections?
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Which condition is NOT indicated for topical administration of sulfonamides?
Which condition is NOT indicated for topical administration of sulfonamides?
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What adverse reaction occurs commonly due to sulfonamides?
What adverse reaction occurs commonly due to sulfonamides?
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Which drug interaction is associated with sulfonamides?
Which drug interaction is associated with sulfonamides?
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What condition should be considered before using sulfonamides in the third trimester of pregnancy?
What condition should be considered before using sulfonamides in the third trimester of pregnancy?
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