Heavy Metals in Medicine Quiz
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Questions and Answers

What is the mode of action of perchloride of mercury (HgCl2)?

Depends on free Hg ions which make coagulation of albumin of bacterial cell forming insoluble protein called albuminate of mercury causing destruction of bacterial cell.

What are the uses of perchloride of mercury (HgCl2)?

It is a very powerful bactericidal disinfectant and was used as a topical antiseptic and disinfectant.

Why has modern medicine deemed perchloride of mercury (HgCl2) unsafe for use?

It is considered unsafe due to its corrosive nature to mucous membranes.

What is the mode of action of silver compounds?

<p>Silver ions readily interact with proteins, amino acid residues, free anions, and receptors on mammalian and bacterial cell membranes, precipitating proteins and interfering with essential metabolic activities of microbial cells.</p> Signup and view all the answers

What is the mode of action of quaternary ammonium compounds (QAC)?

<p>They irreversibly bind to phospholipids in the cell membrane, denature proteins, and impair the permeability of bacterial cells.</p> Signup and view all the answers

Silver is a remarkably safe, nontoxic metal for humans and animals. Uses • It is used in water and medical devices disinfection. Mode of action • Silver metal and inorganic silver compounds ionize in the presence of water, body fluids, and tissue exudates. • Silver ions readily interact with proteins, amino acid residues, free anions, and receptors on mammalian and bacterial cell membranes. • Silver ions precipitate proteins as well as it interferes with essential metabolic activities of microbial cells. 6-Quaternary Ammonium compounds ( QAC) Mode of action • Irreversible bind to phospholipids in the cell membrane. • Denature proteins. • Both impaire the permeability of bacterial cell. Activity range (Uses) • Lethal to G. positive bacteria, at concentrations (0.0005%). • Lethal to G. negative organisms, at concentrations (0.003%) but Ps.

<p>disinfectant</p> Signup and view all the answers

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