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Questions and Answers
What is the mode of action of perchloride of mercury (HgCl2)?
What is the mode of action of perchloride of mercury (HgCl2)?
Depends on free Hg ions which make coagulation of albumin of bacterial cell forming insoluble protein called albuminate of mercury causing destruction of bacterial cell.
What are the uses of perchloride of mercury (HgCl2)?
What are the uses of perchloride of mercury (HgCl2)?
It is a very powerful bactericidal disinfectant and was used as a topical antiseptic and disinfectant.
Why has modern medicine deemed perchloride of mercury (HgCl2) unsafe for use?
Why has modern medicine deemed perchloride of mercury (HgCl2) unsafe for use?
It is considered unsafe due to its corrosive nature to mucous membranes.
What is the mode of action of silver compounds?
What is the mode of action of silver compounds?
What is the mode of action of quaternary ammonium compounds (QAC)?
What is the mode of action of quaternary ammonium compounds (QAC)?
Silver is a remarkably safe, nontoxic metal for humans and animals. Uses • It is used in water and medical devices disinfection. Mode of action • Silver metal and inorganic silver compounds ionize in the presence of water, body fluids, and tissue exudates. • Silver ions readily interact with proteins, amino acid residues, free anions, and receptors on mammalian and bacterial cell membranes. • Silver ions precipitate proteins as well as it interferes with essential metabolic activities of microbial cells. 6-Quaternary Ammonium compounds ( QAC) Mode of action • Irreversible bind to phospholipids in the cell membrane. • Denature proteins. • Both impaire the permeability of bacterial cell. Activity range (Uses) • Lethal to G. positive bacteria, at concentrations (0.0005%). • Lethal to G. negative organisms, at concentrations (0.003%) but Ps.
Silver is a remarkably safe, nontoxic metal for humans and animals. Uses • It is used in water and medical devices disinfection. Mode of action • Silver metal and inorganic silver compounds ionize in the presence of water, body fluids, and tissue exudates. • Silver ions readily interact with proteins, amino acid residues, free anions, and receptors on mammalian and bacterial cell membranes. • Silver ions precipitate proteins as well as it interferes with essential metabolic activities of microbial cells. 6-Quaternary Ammonium compounds ( QAC) Mode of action • Irreversible bind to phospholipids in the cell membrane. • Denature proteins. • Both impaire the permeability of bacterial cell. Activity range (Uses) • Lethal to G. positive bacteria, at concentrations (0.0005%). • Lethal to G. negative organisms, at concentrations (0.003%) but Ps.
Flashcards
Mode of action of HgCl2
Mode of action of HgCl2
HgCl2 forms insoluble mercury albuminate, destroying bacterial cells by coagulating bacterial cell albumin.
HgCl2 uses
HgCl2 uses
Strong bactericidal disinfectant, previously used as antiseptic and disinfectant.
HgCl2 safety concern
HgCl2 safety concern
HgCl2 is now deemed unsafe due to its corrosive effect on mucous membranes.
Silver compounds' mode of action
Silver compounds' mode of action
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QAC mode of action
QAC mode of action
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Silver use in disinfection
Silver use in disinfection
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