Subcutaneous Injection Pharmacology

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5 Questions

What is the primary difference between the sublingual and buccal routes of drug administration?

Sublingual allows the drug to dissolve under the tongue, while buccal places it between the cheek and gum

Which of the following is an advantage of both the buccal and sublingual routes?

No first-pass hepatic metabolism

Which of the following is not true about drugs administered via the buccal or sublingual routes?

They are subject to first-pass hepatic metabolism

Where is the drug placed when using the sublingual route?

Under the tongue

Which statement correctly describes the buccal route of drug administration?

The medicament is placed between the cheek and the gum

Study Notes

Subcutaneous (SC)

  • Slower absorption of drugs compared to Intramuscular (IM) sites
  • Suitable for administering drugs that don't require rapid response and those that degrade when taken orally, such as insulin and sodium heparin
  • Aqueous solutions are rapidly absorbed from SC sites
  • Depot preparations from SC sites are absorbed slowly
  • Irritant drugs are not suitable for SC injection

Enteral Routes

  • Buccal or Sublingual (SL) Routes
    • Sublingual route involves placing the drug under the tongue to dissolve
    • Buccal route involves placing the medication between the cheek and gum
    • No first-pass hepatic metabolism occurs in these routes
    • No degradation of drugs occurs in these routes, unlike in the Gastrointestinal Tract (GIT)

Learn about the absorption and administration of drugs through subcutaneous injection, including its advantages and disadvantages. Discover the types of drugs suitable for SC injection and their characteristics.

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