Subcutaneous Injection Pharmacology
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Questions and Answers

What is the primary difference between the sublingual and buccal routes of drug administration?

  • Buccal allows the drug to dissolve under the tongue, while sublingual places it between the cheek and gum
  • Buccal involves swallowing the drug, while sublingual requires keeping the drug on the tongue
  • Sublingual allows the drug to dissolve under the tongue, while buccal places it between the cheek and gum (correct)
  • Sublingual involves swallowing the drug, while buccal requires keeping the drug on the tongue
  • Which of the following is an advantage of both the buccal and sublingual routes?

  • Rapid degradation of drug in the GIT
  • No need for hydration when administering
  • Reduced absorption compared to oral routes
  • No first-pass hepatic metabolism (correct)
  • Which of the following is not true about drugs administered via the buccal or sublingual routes?

  • They are subject to first-pass hepatic metabolism (correct)
  • They provide rapid onset of action
  • They are placed under the tongue or between the cheek and gum
  • They avoid degradation encountered in the GIT
  • Where is the drug placed when using the sublingual route?

    <p>Under the tongue</p> Signup and view all the answers

    Which statement correctly describes the buccal route of drug administration?

    <p>The medicament is placed between the cheek and the gum</p> Signup and view all the answers

    Study Notes

    Subcutaneous (SC)

    • Slower absorption of drugs compared to Intramuscular (IM) sites
    • Suitable for administering drugs that don't require rapid response and those that degrade when taken orally, such as insulin and sodium heparin
    • Aqueous solutions are rapidly absorbed from SC sites
    • Depot preparations from SC sites are absorbed slowly
    • Irritant drugs are not suitable for SC injection

    Enteral Routes

    • Buccal or Sublingual (SL) Routes
      • Sublingual route involves placing the drug under the tongue to dissolve
      • Buccal route involves placing the medication between the cheek and gum
      • No first-pass hepatic metabolism occurs in these routes
      • No degradation of drugs occurs in these routes, unlike in the Gastrointestinal Tract (GIT)

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    Description

    Learn about the absorption and administration of drugs through subcutaneous injection, including its advantages and disadvantages. Discover the types of drugs suitable for SC injection and their characteristics.

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