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Questions and Answers
What is the primary difference between the sublingual and buccal routes of drug administration?
What is the primary difference between the sublingual and buccal routes of drug administration?
- Buccal allows the drug to dissolve under the tongue, while sublingual places it between the cheek and gum
- Buccal involves swallowing the drug, while sublingual requires keeping the drug on the tongue
- Sublingual allows the drug to dissolve under the tongue, while buccal places it between the cheek and gum (correct)
- Sublingual involves swallowing the drug, while buccal requires keeping the drug on the tongue
Which of the following is an advantage of both the buccal and sublingual routes?
Which of the following is an advantage of both the buccal and sublingual routes?
- Rapid degradation of drug in the GIT
- No need for hydration when administering
- Reduced absorption compared to oral routes
- No first-pass hepatic metabolism (correct)
Which of the following is not true about drugs administered via the buccal or sublingual routes?
Which of the following is not true about drugs administered via the buccal or sublingual routes?
- They are subject to first-pass hepatic metabolism (correct)
- They provide rapid onset of action
- They are placed under the tongue or between the cheek and gum
- They avoid degradation encountered in the GIT
Where is the drug placed when using the sublingual route?
Where is the drug placed when using the sublingual route?
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Which statement correctly describes the buccal route of drug administration?
Which statement correctly describes the buccal route of drug administration?
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Study Notes
Subcutaneous (SC)
- Slower absorption of drugs compared to Intramuscular (IM) sites
- Suitable for administering drugs that don't require rapid response and those that degrade when taken orally, such as insulin and sodium heparin
- Aqueous solutions are rapidly absorbed from SC sites
- Depot preparations from SC sites are absorbed slowly
- Irritant drugs are not suitable for SC injection
Enteral Routes
- Buccal or Sublingual (SL) Routes
- Sublingual route involves placing the drug under the tongue to dissolve
- Buccal route involves placing the medication between the cheek and gum
- No first-pass hepatic metabolism occurs in these routes
- No degradation of drugs occurs in these routes, unlike in the Gastrointestinal Tract (GIT)
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Description
Learn about the absorption and administration of drugs through subcutaneous injection, including its advantages and disadvantages. Discover the types of drugs suitable for SC injection and their characteristics.
