Subcutaneous Biosimilar Infliximab Quiz
25 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the mechanism of action of Vedolizumab?

  • Targets the cellular adhesion molecule α4-integrin
  • Inhibits signaling through TNFα receptors
  • Binds to soluble TNF-α
  • Blocks the entry of lymphocytes into mucosal tissues (correct)
  • What adverse effect is NOT commonly associated with Vedolizumab?

  • Blurred vision and dizziness
  • Fast, pounding heartbeat (correct)
  • Joint pain and headache
  • Yellow skin or eyes
  • Which biologic agent targets the cellular adhesion molecule α4-integrin?

  • Vedolizumab
  • Natalizumab (correct)
  • Adalimumab
  • Certolizumab pegol
  • What serious risk is associated with Natalizumab?

    <p>Progressive multifocal leukoencephalopathy</p> Signup and view all the answers

    How does Certolizumab pegol inhibit TNF-α?

    <p>By binding to soluble TNF-α</p> Signup and view all the answers

    What is the mechanism of action of Vedolizumab in the treatment of inflammatory bowel disease (IBD)?

    <p>Prevents lymphocytes from egressing from lymphoid organs</p> Signup and view all the answers

    Which adverse effect is NOT commonly associated with Natalizumab therapy?

    <p>Joint pain</p> Signup and view all the answers

    Which enzyme is involved in the metabolism of Etrasimod, one of the new treatments for IBD?

    <p>CYP3A4</p> Signup and view all the answers

    What type of monoclonal antibody is Mirikizumab, another new treatment for IBD?

    <p>IgG4</p> Signup and view all the answers

    Which biologic agent is known for binding to the S1P-receptor and preventing lymphocytes from egressing from lymphoid organs?

    <p>Vedolizumab</p> Signup and view all the answers

    What distinguishes the delivery of the biosimilar of infliximab from the original drug?

    <p>It is delivered subcutaneously</p> Signup and view all the answers

    Which of the following is NOT a possible side effect of the biosimilar of infliximab according to the text?

    <p>Changes in taste perception</p> Signup and view all the answers

    What distinguishes Adalimumab from infliximab in terms of its structure?

    <p>Adalimumab is fully humanized</p> Signup and view all the answers

    Which cytokine do biologic agents like Adalimumab and infliximab target?

    <p>TNF-α</p> Signup and view all the answers

    Among the listed possible side effects, which one warrants immediate medical attention?

    <p>Warm, red, swollen, or painful skin</p> Signup and view all the answers

    Which enzyme is responsible for the metabolism of thiopurine methyltransferase (TPMT) to 6-methyl-mercaptopurine (6-MMP)?

    <p>Hypoxanthine–guanine phosphoribosyl transferase (HGPRT)</p> Signup and view all the answers

    Which biologic agent for IBD acts by blocking the p19 subunit of interleukin-23?

    <p>Risankizumab-rzaa</p> Signup and view all the answers

    What is a potential adverse effect associated with vedolizumab?

    <p>Swelling of the face and throat</p> Signup and view all the answers

    What is the primary mode of action of Infliximab, a biologic agent that targets TNF-α?

    <p>Binds TNF-α and inhibits its inflammatory effects</p> Signup and view all the answers

    Which biologic agent is a TNF-α inhibitor used in the treatment of IBD?

    <p>Adalimumab</p> Signup and view all the answers

    What is the main function of Vedolizumab in the treatment of inflammatory bowel disease (IBD)?

    <p>Blocks lymphocyte trafficking into the gut</p> Signup and view all the answers

    What is a possible adverse effect associated with Infliximab?

    <p>Loss of response over time</p> Signup and view all the answers

    What is a common adverse effect associated with natalizumab?

    <p>Increased risk of infections</p> Signup and view all the answers

    Which biologic agent for IBD interacts with the IL-23 receptor to prevent its action?

    <p>Ustekinumab</p> Signup and view all the answers

    Which biologic agent targets TNF-α and has been FDA approved around 2023?

    <p>Infliximab</p> Signup and view all the answers

    More Like This

    Infliximab (Remicade) Flashcards
    6 questions

    Infliximab (Remicade) Flashcards

    WellConnectedComputerArt avatar
    WellConnectedComputerArt
    Use Quizgecko on...
    Browser
    Browser