Podcast
Questions and Answers
What is the mechanism of action of Vedolizumab?
What is the mechanism of action of Vedolizumab?
- Targets the cellular adhesion molecule α4-integrin
- Inhibits signaling through TNFα receptors
- Binds to soluble TNF-α
- Blocks the entry of lymphocytes into mucosal tissues (correct)
What adverse effect is NOT commonly associated with Vedolizumab?
What adverse effect is NOT commonly associated with Vedolizumab?
- Blurred vision and dizziness
- Fast, pounding heartbeat (correct)
- Joint pain and headache
- Yellow skin or eyes
Which biologic agent targets the cellular adhesion molecule α4-integrin?
Which biologic agent targets the cellular adhesion molecule α4-integrin?
- Vedolizumab
- Natalizumab (correct)
- Adalimumab
- Certolizumab pegol
What serious risk is associated with Natalizumab?
What serious risk is associated with Natalizumab?
How does Certolizumab pegol inhibit TNF-α?
How does Certolizumab pegol inhibit TNF-α?
What is the mechanism of action of Vedolizumab in the treatment of inflammatory bowel disease (IBD)?
What is the mechanism of action of Vedolizumab in the treatment of inflammatory bowel disease (IBD)?
Which adverse effect is NOT commonly associated with Natalizumab therapy?
Which adverse effect is NOT commonly associated with Natalizumab therapy?
Which enzyme is involved in the metabolism of Etrasimod, one of the new treatments for IBD?
Which enzyme is involved in the metabolism of Etrasimod, one of the new treatments for IBD?
What type of monoclonal antibody is Mirikizumab, another new treatment for IBD?
What type of monoclonal antibody is Mirikizumab, another new treatment for IBD?
Which biologic agent is known for binding to the S1P-receptor and preventing lymphocytes from egressing from lymphoid organs?
Which biologic agent is known for binding to the S1P-receptor and preventing lymphocytes from egressing from lymphoid organs?
What distinguishes the delivery of the biosimilar of infliximab from the original drug?
What distinguishes the delivery of the biosimilar of infliximab from the original drug?
Which of the following is NOT a possible side effect of the biosimilar of infliximab according to the text?
Which of the following is NOT a possible side effect of the biosimilar of infliximab according to the text?
What distinguishes Adalimumab from infliximab in terms of its structure?
What distinguishes Adalimumab from infliximab in terms of its structure?
Which cytokine do biologic agents like Adalimumab and infliximab target?
Which cytokine do biologic agents like Adalimumab and infliximab target?
Among the listed possible side effects, which one warrants immediate medical attention?
Among the listed possible side effects, which one warrants immediate medical attention?
Which enzyme is responsible for the metabolism of thiopurine methyltransferase (TPMT) to 6-methyl-mercaptopurine (6-MMP)?
Which enzyme is responsible for the metabolism of thiopurine methyltransferase (TPMT) to 6-methyl-mercaptopurine (6-MMP)?
Which biologic agent for IBD acts by blocking the p19 subunit of interleukin-23?
Which biologic agent for IBD acts by blocking the p19 subunit of interleukin-23?
What is a potential adverse effect associated with vedolizumab?
What is a potential adverse effect associated with vedolizumab?
What is the primary mode of action of Infliximab, a biologic agent that targets TNF-α?
What is the primary mode of action of Infliximab, a biologic agent that targets TNF-α?
Which biologic agent is a TNF-α inhibitor used in the treatment of IBD?
Which biologic agent is a TNF-α inhibitor used in the treatment of IBD?
What is the main function of Vedolizumab in the treatment of inflammatory bowel disease (IBD)?
What is the main function of Vedolizumab in the treatment of inflammatory bowel disease (IBD)?
What is a possible adverse effect associated with Infliximab?
What is a possible adverse effect associated with Infliximab?
What is a common adverse effect associated with natalizumab?
What is a common adverse effect associated with natalizumab?
Which biologic agent for IBD interacts with the IL-23 receptor to prevent its action?
Which biologic agent for IBD interacts with the IL-23 receptor to prevent its action?
Which biologic agent targets TNF-α and has been FDA approved around 2023?
Which biologic agent targets TNF-α and has been FDA approved around 2023?
