Infliximab (Remicade) Flashcards

What is the drug classification of Infliximab?

What is Infliximab used to treat?

What is the primary action of Infliximab?

Which of the following are adverse effects of Infliximab? (Select all that apply)

Nursing implications include administering Infliximab in a setting where personnel and supplies for treatment of __________ reactions are available.

Infliximab should be discontinued if severe reactions occur.

Infliximab (Remicade) Overview

Classification: Tumor necrosis factor alpha (TNF-alpha) blocking agent, used in treatment protocols.
Therapeutic Uses: Effective for managing rheumatoid arthritis (RA) and Crohn's disease, providing relief from symptoms and inflammation.

Mechanism of Action

Functions by inhibiting TNF-alpha, leading to significant anti-inflammatory effects in the body.

Adverse Effects

Can trigger hypersensitivity reactions, necessitating awareness and monitoring.
Cardiovascular/Respiratory: May cause dyspnea, hypotension, and heart failure (HF).
Dermatological: Possible skin reactions include urticaria (hives).
Risk of infections and malignancies, particularly lymphoma, requiring assessment and caution.

Nursing Implications

Administer infliximab where trained personnel and emergency supplies (epinephrine, antihistamines, corticosteroids) are accessible to manage hypersensitivity reactions.
Be prepared to discontinue therapy if severe adverse reactions occur, ensuring patient safety.

Test your knowledge about Infliximab, a TNF-alpha blocking agent used to treat rheumatoid arthritis (RA) and Crohn's disease. This quiz covers its drug classification, mechanism of action, uses, and potential adverse effects. Perfect for students and healthcare professionals!