Infliximab (Remicade) Flashcards
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Questions and Answers

What is the drug classification of Infliximab?

  • Corticosteroid
  • Analgesic
  • Anti-inflammatory agent
  • Tumor necrosis factor alpha blocking agent (correct)

What is Infliximab used to treat?

Rheumatoid arthritis and Crohn's disease

What is the primary action of Infliximab?

Inhibits TNF-alpha

Which of the following are adverse effects of Infliximab? (Select all that apply)

<p>Hypersensitivity reactions (A), Hypotension (B), Urticaria (D)</p> Signup and view all the answers

Nursing implications include administering Infliximab in a setting where personnel and supplies for treatment of __________ reactions are available.

<p>hypersensitivity</p> Signup and view all the answers

Infliximab should be discontinued if severe reactions occur.

<p>True (A)</p> Signup and view all the answers

Study Notes

Infliximab (Remicade) Overview

  • Classification: Tumor necrosis factor alpha (TNF-alpha) blocking agent, used in treatment protocols.
  • Therapeutic Uses: Effective for managing rheumatoid arthritis (RA) and Crohn's disease, providing relief from symptoms and inflammation.

Mechanism of Action

  • Functions by inhibiting TNF-alpha, leading to significant anti-inflammatory effects in the body.

Adverse Effects

  • Can trigger hypersensitivity reactions, necessitating awareness and monitoring.
  • Cardiovascular/Respiratory: May cause dyspnea, hypotension, and heart failure (HF).
  • Dermatological: Possible skin reactions include urticaria (hives).
  • Risk of infections and malignancies, particularly lymphoma, requiring assessment and caution.

Nursing Implications

  • Administer infliximab where trained personnel and emergency supplies (epinephrine, antihistamines, corticosteroids) are accessible to manage hypersensitivity reactions.
  • Be prepared to discontinue therapy if severe adverse reactions occur, ensuring patient safety.

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Description

Test your knowledge about Infliximab, a TNF-alpha blocking agent used to treat rheumatoid arthritis (RA) and Crohn's disease. This quiz covers its drug classification, mechanism of action, uses, and potential adverse effects. Perfect for students and healthcare professionals!

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