Structure of Chromosomes and Chromatin

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Questions and Answers

What is the primary purpose of mitosis?

  • To produce gametes
  • To reduce the chromosome number
  • To maintain the same chromosome number in daughter cells (correct)
  • To facilitate genetic recombination

During which phase of mitosis do sister chromatids separate?

  • Telophase
  • Anaphase (correct)
  • Metaphase
  • Prophase

What significant event happens during meiosis that is not part of mitosis?

  • Restructuring of the nuclear membrane
  • Duplication of sister chromatids
  • Formation of spindle fibers
  • Halving of the chromosome number (correct)

What role do the spindle fibers play during mitosis?

<p>They aid in moving chromosomes to opposite poles (C)</p> Signup and view all the answers

Which process leads to genetic variation among gametes?

<p>Crossing over (D)</p> Signup and view all the answers

What occurs during the telophase of mitosis?

<p>Spindle fibers fully disassemble (B), Nuclear membrane reappears (C)</p> Signup and view all the answers

Which cell division process is responsible for asexual reproduction?

<p>Mitosis (C)</p> Signup and view all the answers

Which statement best describes cytokinesis?

<p>It occurs alongside karyokinesis. (C)</p> Signup and view all the answers

What is the name of the complex formed by DNA and proteins in the nucleus?

<p>Chromatin (B)</p> Signup and view all the answers

What discovery did Walther Flemming make related to cell division?

<p>He named the process mitosis. (D)</p> Signup and view all the answers

What role do histones play in relation to DNA?

<p>They help in coiling and packaging DNA. (C)</p> Signup and view all the answers

During which phase of the cell cycle do chromosomes duplicate?

<p>Synthesis Phase (C)</p> Signup and view all the answers

What is the purpose of the centromere in a chromosome?

<p>Attachment of spindle fibers during cell division (A)</p> Signup and view all the answers

Which of the following statements about genes is correct?

<p>Genes are units of heredity transferred from parents to offspring. (B)</p> Signup and view all the answers

Which phase of the cell cycle is known as the resting phase?

<p>Interphase (A)</p> Signup and view all the answers

What type of cell division results in haploid cells?

<p>Meiosis (B)</p> Signup and view all the answers

Flashcards

Chromatin

Complex of DNA and proteins, appearing as long threads when the cell isn't dividing; it condenses into chromosomes when the cell divides.

Chromosome

A discrete unit within the nucleus, containing a long DNA molecule associated with proteins. Visible during cell division.

Sister Chromatids

Two identical copies of a chromosome, formed during DNA replication, joined at the centromere.

Centromere

The point where two sister chromatids attach.

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Gene

Specific DNA sequence on a chromosome that encodes for a particular protein, influencing a specific trait.

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Mitosis

Cell division producing diploid cells for growth and repair.

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Interphase

Non-dividing phase of the cell cycle, consisting of growth (G1, G2) and DNA synthesis (S) phases.

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Cell Cycle

Series of events in creating two copies of a cell through division.

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Karyokinesis

The division of the nucleus during mitosis, involving four distinct phases: prophase, metaphase, anaphase, and telophase.

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Cytokinesis

Division of the cytoplasm after karyokinesis, resulting in two separate daughter cells.

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Prophase

The first stage of mitosis, where chromosomes condense, spindle fibers form, and the nuclear membrane disappears.

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Metaphase

The second stage of mitosis, where chromosomes line up at the equator of the cell, attached to spindle fibers.

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Anaphase

The third stage of mitosis, where sister chromatids separate and move to opposite poles of the cell.

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Telophase

The final stage of mitosis, where nuclear membranes reform around the separated chromosomes, spindle fibers disappear, and the cell begins to divide.

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Study Notes

Structure of Chromosomes

  • The nucleus contains most of the cell's DNA, organized into discrete units called chromosomes.
  • Each chromosome contains one long DNA molecule associated with many proteins.
  • This DNA and protein complex is called chromatin.
  • When a cell is not dividing, chromatin appears as a long thread.
  • When a cell is dividing, chromatin condenses to form chromosomes.
  • Chromatin is a colored body (chroma) and a body (soma).

Chromatin

  • Chromatin material forms a fibre made of two components:
    • DNA, made of repeating nucleotides (phosphate, sugar, nitrogenous base).
    • Nucleotides are joined by complementary nitrogenous bases: Adenine, Guanine, Cytosine, Thymine.

Histones

  • Histones are proteins that help coil and package DNA into structural units called nucleosomes.
  • Nucleosomes contain eight histone proteins.

Chromosome Structure

  • A chromosome, in its condensed form during cell division, consists of two sister chromatids joined at the centromere.
  • The centromere is the point of attachment for spindle fibres during cell division.

Genes

  • Genes are specific sequences of nucleotides on a chromosome.
  • They encode particular proteins, expressing specific features of the body.
  • Genes are units of heredity passed from parents to offspring.

Cell Cycle

  • The cell cycle describes a series of events leading to DNA duplication and cell division, producing two daughter cells.
  • The cell cycle consists of two phases:
    • Interphase (non-dividing phase):
      • First growth phase (G1): Resting phase, no chromosome change.
      • Synthesis phase (S): DNA synthesis and chromosome duplication.
      • Second growth phase (G2): More RNA synthesis.
    • M-phase (dividing phase):
      • Mitosis and cytokinesis

Mitosis

  • Mitosis is a type of cell division where a parent cell divides into two identical daughter cells.

  • Chromosome number remains the same after mitosis.

  • Mitosis has four phases:

    • Prophase
    • Metaphase
    • Anaphase
    • Telophase
  • Mitosis is crucial for:

    • Growth
    • Repair
    • Replacement
    • Asexual reproduction

Meiosis

  • Meiosis is the cell division that produces sex cells (gametes).
  • Meiosis reduces the chromosome number to half (haploid).
  • Meiosis is important for:
    • Halving chromosome numbers
    • Mixing up genes

Meiosis Phases

  • Meiosis involves two divisions:

    • Prophase I, Metaphase I, Anaphase I, Telophase I (First division)
    • Prophase II, Metaphase II, Anaphase II, Telophase II (Second division)
  • Crossing over and mixing of maternal and paternal chromosomes happen during meiosis.

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