Medical Genetics Committee 3 Lecture 1-2: Chromosome Structure and Classification

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Questions and Answers

What is the basic structural unit of chromatin called?

  • Nucleosome (correct)
  • MARs
  • Histone H5
  • SARs

Which type of chromatin is transcriptionally active?

  • Euchromatin (correct)
  • Heterokromatin
  • Histone acetylation
  • Histone proteins

What is the function of histone acetyltransferase (HAT) in relation to histones?

  • Transcription inhibition
  • Gene repression
  • Gene activation (correct)
  • DNA packaging

Which proteins are considered the major proteins of chromatin?

<p>Histone proteins (B)</p>
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What happens during histone methylation?

<p>Addition of methyl groups to histone tails (D)</p>
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Which region of the chromosome is associated with DNA packaging and structure?

<p>Scaffold attachment regions (SARs) (C)</p>
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What is the function of the SWI/SNF complex?

<p>Loosen DNA-histone contact (C)</p>
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What is the structure that is 2 nm in diameter in DNA packaging?

<p>Nucleosome (B)</p>
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Which proteins make up the 'Beads on a string' structure in chromatin?

<p>Histone H1 (A)</p>
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What does HMG stand for in the context of chromatin structure?

<p>High Mobility Group (C)</p>
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Where is the localization of HMG proteins predominantly found?

<p>Protein scaffold (D)</p>
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How many pairs of chromosomes do humans have?

<p>23 pairs (A)</p>
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