Medical Genetics Committee 3 Lecture 1-2: Chromosome Structure and Classification
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Questions and Answers

What is the basic structural unit of chromatin called?

  • Nucleosome (correct)
  • MARs
  • Histone H5
  • SARs

    • Which type of chromatin is transcriptionally active?

  • Euchromatin (correct)
  • Heterokromatin
  • Histone acetylation
  • Histone proteins

    • What is the function of histone acetyltransferase (HAT) in relation to histones?

  • Transcription inhibition
  • Gene repression
  • Gene activation (correct)
  • DNA packaging

    • Which proteins are considered the major proteins of chromatin?

    <p>Histone proteins</p> Signup and view all the answers

    What happens during histone methylation?

    <p>Addition of methyl groups to histone tails</p> Signup and view all the answers

    Which region of the chromosome is associated with DNA packaging and structure?

    <p>Scaffold attachment regions (SARs)</p> Signup and view all the answers

    What is the function of the SWI/SNF complex?

    <p>Loosen DNA-histone contact</p> Signup and view all the answers

    What is the structure that is 2 nm in diameter in DNA packaging?

    <p>Nucleosome</p> Signup and view all the answers

    Which proteins make up the 'Beads on a string' structure in chromatin?

    <p>Histone H1</p> Signup and view all the answers

    What does HMG stand for in the context of chromatin structure?

    <p>High Mobility Group</p> Signup and view all the answers

    Where is the localization of HMG proteins predominantly found?

    <p>Protein scaffold</p> Signup and view all the answers

    How many pairs of chromosomes do humans have?

    <p>23 pairs</p> Signup and view all the answers

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