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Medical Genetics Committee 3 Lecture 1-2: Chromosome Structure and Classification

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Medical Genetics Committee 3 Lecture 1-2: Chromosome Structure and Classification

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Questions and Answers

What is the basic structural unit of chromatin called?

Nucleosome (correct)

MARs

Histone H5

SARs

Which type of chromatin is transcriptionally active?

Euchromatin (correct)

Heterokromatin

Histone acetylation

Histone proteins

What is the function of histone acetyltransferase (HAT) in relation to histones?

Transcription inhibition

Gene repression

Gene activation (correct)

DNA packaging

Which proteins are considered the major proteins of chromatin?

Histone proteins Signup and view all the answers

What happens during histone methylation?

Addition of methyl groups to histone tails Signup and view all the answers

Which region of the chromosome is associated with DNA packaging and structure?

Scaffold attachment regions (SARs) Signup and view all the answers

What is the function of the SWI/SNF complex?

Loosen DNA-histone contact Signup and view all the answers

What is the structure that is 2 nm in diameter in DNA packaging?

Nucleosome Signup and view all the answers

Which proteins make up the 'Beads on a string' structure in chromatin?

Histone H1 Signup and view all the answers

What does HMG stand for in the context of chromatin structure?

High Mobility Group Signup and view all the answers

Where is the localization of HMG proteins predominantly found?

Protein scaffold Signup and view all the answers

How many pairs of chromosomes do humans have?

23 pairs Signup and view all the answers