DNA Packaging and Chromatin Structure Quiz

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Questions and Answers

What type of chromatin is more highly condensed and associated with areas of the chromosomes that are not expressed?

  • Euchromatin
  • Nucleosomes
  • Heterochromatin (correct)
  • Sister chromatids

What is the primary genetic material in most organisms?

  • Nucleosomes
  • Double-stranded DNA (correct)
  • Histone H1
  • Heterochromatin

What process allows the assessment of chromosome abnormalities by identifying translocations, deletions, inversions, and duplications?

  • Histone association
  • Karyotype analysis (correct)
  • Nucleosome condensation
  • Euchromatin formation

Which component is NOT part of a nucleotide?

<p>Hydrogen group (D)</p> Signup and view all the answers

During which phase of the cell cycle is all the DNA highly condensed to allow separation of the sister chromatids?

<p>Mitosis (B)</p> Signup and view all the answers

Which nitrogenous base is present in RNA but not in DNA?

<p>Uracil (C)</p> Signup and view all the answers

What is the sugar component of DNA nucleotides?

<p>Deoxyribose (D)</p> Signup and view all the answers

How many hydrogen bonds are there in a G ≡ C base pair?

<p>Three (D)</p> Signup and view all the answers

What type of RNA acts as the carrier of genetic information from DNA to the translational machinery?

<p>Messenger RNA (mRNA) (D)</p> Signup and view all the answers

What is the most abundant class of RNA molecule, making up around 85% of total cellular RNA?

<p>Ribosomal RNA (rRNA) (D)</p> Signup and view all the answers

What is the primary function of histone H1 in the context of chromatin structure?

<p>To help package nucleosomes into a solenoid-like structure (C)</p> Signup and view all the answers

Which type of chromatin corresponds to loosely associated nucleosomes (10-nm fibers) and is more available for gene expression?

<p>Euchromatin (D)</p> Signup and view all the answers

What is the purpose of banding techniques in assessing chromosome abnormalities?

<p>To identify translocations, deletions, inversions, and duplications (B)</p> Signup and view all the answers

During which phase of the cell cycle does all the DNA become highly condensed to allow separation of the sister chromatids?

<p>Mitosis (C)</p> Signup and view all the answers

What is the sugar component of RNA nucleotides?

<p>ribose (A)</p> Signup and view all the answers

What is the function of ribosomal RNA (rRNA)?

<p>Associated with ribosomes and makes up about 85% of total cellular RNA (A)</p> Signup and view all the answers

Which base pair in DNA has three hydrogen bonds between them?

<p>G ≡ C (C)</p> Signup and view all the answers

What are the main types of RNA molecules found in cells?

<p>messenger RNA (mRNA), small nuclear RNA (snRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA) (D)</p> Signup and view all the answers

What is the characteristic structure of purines and pyrimidines?

<p>Double-ring structure for both purines and pyrimidines (D)</p> Signup and view all the answers

What is the role of transfer RNA (tRNA) in protein synthesis?

<p>Provides specificity for the insertion of correct amino acids into proteins (A)</p> Signup and view all the answers

Flashcards

What is Heterochromatin?

Heterochromatin is a highly condensed form of chromatin that is typically not expressed. It's involved in regulating gene expression and structural organization, particularly in the nucleus.

What is the primary genetic material?

Double-stranded DNA is the primary genetic material in most organisms. It carries the genetic code that determines an organism's traits.

What is Karyotype analysis?

Karyotype analysis is a technique used to assess chromosome abnormalities by examining the number and structure of chromosomes in a cell. It identifies changes like translocations, deletions, inversions, and duplications.

What is a nucleotide?

A nucleotide is a building block of DNA and RNA. It comprises three components: a phosphate group, a sugar molecule (deoxyribose in DNA, ribose in RNA), and a nitrogenous base.

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During which phase of the cell cycle does DNA condense?

Mitosis is a crucial process in cell division where the duplicated chromosomes are separated into two identical daughter cells.

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Which nitrogenous base is unique to RNA?

Uracil is a nitrogenous base found in RNA but not in DNA. It pairs with adenine.

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What is the sugar component of DNA?

Deoxyribose is a sugar molecule that forms the backbone of DNA. It differs from ribose, the sugar in RNA, by the absence of an oxygen atom at the 2' carbon.

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How many hydrogen bonds are in a G-C base pair?

There are three hydrogen bonds between guanine (G) and cytosine (C) in a DNA base pair. This makes the G-C bond stronger than the A-T bond, which has two hydrogen bonds.

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What is the role of mRNA?

Messenger RNA (mRNA) is a type of RNA that carries genetic information from DNA in the nucleus to the ribosomes in the cytoplasm for protein synthesis.

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What is the function of rRNA?

Ribosomal RNA (rRNA) is a type of RNA that is a major component of ribosomes, the cellular machinery responsible for protein synthesis. It makes up about 85% of total cellular RNA.

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What is the role of Histone H1?

Histone H1 acts as a linker histone in chromatin structure. It helps package nucleosomes into a solenoid-like structure, further compacting the DNA.

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What is Euchromatin?

Euchromatin is a less condensed form of chromatin that is actively transcribed. It's associated with areas of the genome where genes are expressed.

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What is the purpose of chromosome banding?

Banding techniques are vital in assessing chromosome abnormalities. They create distinct banding patterns on chromosomes, which are used to identify changes like translocations, deletions, inversions, and duplications.

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During which phase of the cell cycle does DNA condense?

Mitosis is the phase of the cell cycle where DNA condenses to allow for the separation of duplicated chromosomes into two identical daughter cells.

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What is the sugar component of RNA?

Ribose is a five-carbon sugar that forms the backbone of RNA molecules. It differs from deoxyribose, the sugar in DNA, by the presence of an oxygen atom at the 2' carbon.

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What is the function of rRNA?

Ribosomal RNA (rRNA) is a major component of ribosomes, the cellular machinery responsible for protein synthesis. It makes up about 85% of total cellular RNA.

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Which base pair in DNA has three hydrogen bonds?

Guanine (G) and cytosine (C) form a base pair in DNA, with three hydrogen bonds between them. This makes the G-C bond stronger than the bond between adenine (A) and thymine (T).

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What are the main types of RNA?

Messenger RNA (mRNA), transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA) are the main types of RNA found in cells, each playing a crucial role in gene expression and protein synthesis.

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Describe the structure of purines and pyrimidines.

Purines and pyrimidines are two types of nitrogenous bases found in DNA and RNA. Purines, like adenine (A) and guanine (G), have a double-ring structure, whereas pyrimidines, like cytosine (C) and thymine (T) (or uracil in RNA), have a single-ring structure.

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What is the role of tRNA in protein synthesis?

Transfer RNA (tRNA) is a type of RNA that plays a crucial role in protein synthesis by acting as an adapter molecule. It delivers the correct amino acid to the ribosome, where it's incorporated into a growing polypeptide chain.

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