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Questions and Answers
What condition is particularly associated with the antibiotic streptomycin?
What condition is particularly associated with the antibiotic streptomycin?
Which of the following is a potential risk when administering antibiotics at high doses?
Which of the following is a potential risk when administering antibiotics at high doses?
What concurrent treatment may increase the risk of neuromuscular paralysis when administered with high doses of antibiotics?
What concurrent treatment may increase the risk of neuromuscular paralysis when administered with high doses of antibiotics?
Which of the following statements is NOT true regarding the side effects of antibiotics?
Which of the following statements is NOT true regarding the side effects of antibiotics?
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What event related to antibiotics should be considered uncommon?
What event related to antibiotics should be considered uncommon?
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What is a potential consequence of producing a protein with altered biological function?
What is a potential consequence of producing a protein with altered biological function?
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Which factor may influence the alteration of protein production in bacteria?
Which factor may influence the alteration of protein production in bacteria?
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How might a change in protein function affect a bacterium?
How might a change in protein function affect a bacterium?
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Why is the production of proteins with altered functions significant in bacteria?
Why is the production of proteins with altered functions significant in bacteria?
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What can be a result of an abnormal protein impacting bacterial metabolism?
What can be a result of an abnormal protein impacting bacterial metabolism?
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Study Notes
Streptomycin Side Effects
- Altered protein production can disrupt bacterial metabolism.
- Vertigo is a potential side effect, particularly with streptomycin.
- High-dose, rapid infusion or concurrent neuromuscular blockers can cause neuromuscular paralysis.
Streptomycin Combination Therapies
- Streptomycin and tetracycline are used to treat plague, tularemia, and sometimes brucellosis.
- Streptomycin and penicillin are used to treat enterococcal and viridans streptococcal endocarditis.
Gentamicin Properties and Uses
- Isolated from Micromonospora purpurea.
- Effective against gram-positive and gram-negative bacteria.
- Used alone or synergistically with beta-lactam antibiotics against various gram-negative rods (e.g., Pseudomonas, Proteus, Enterobacter, Klebsiella, Serratia, Stenotrophomonas).
- Clinically used to treat Pseudomonas aeruginosa respiratory infections in cystic fibrosis patients (inhalation route minimizes nephrotoxicity and ototoxicity due to reduced systemic absorption).
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Description
Explore the side effects and therapeutic uses of Streptomycin and Gentamicin in this quiz. Learn about their properties, combination therapies, and effects on various bacterial infections. Perfect for students in pharmacology and microbiology courses.
