18 Questions
What maintains the physical attachments between homologous chromosomes during late prophase?
Chiasmata and sister chromatid cohesion
What occurs in the first meiotic division to the parental homologs?
They are disjoined to reduce ploidy to the haploid state
What leads to genetic exchange during meiosis?
Recombination
What is extruded as a polar body during oocyte meiosis?
One of the two end products of each division
In which part of the adult hermaphrodite anterior gonad arm does a syncytium form due to incomplete cytokinesis?
Distal germ line with a central canal called rachis
Which structures specifically disjoin in the second meiotic division?
Sister chromatids
Where are Germline Stem Cells (GSCs) located in C.elegans?
Close to the Distal Tip Cell (DTC)
What is the function of the Distal Tip Cell (DTC) in C.elegans?
Regulating the germline stem cells
In which zone do cells transition from mitosis to meiosis in the C.elegans germ line?
Germline transition zone
What is the role of DSBs in meiotic prophase of oogenesis in C.elegans?
Formation of homologous recombination
Which structure anchors the ventral uterine precursor (VU) in C.elegans?
Anchor cell (AC)
What is the main function of Germline Stem Cells (GSCs) in C.elegans?
Control of mitosis progression
What is the main function of the Distal Tip Cell in the C.elegans germline stem cell niche?
Promoting mitosis and inhibiting meiosis of germ cells
Why is promoting mitosis of Germline Stem Cells (GSCs) important within the niche?
To maintain the pool of stem cells
How is mitosis maintained by the Distal Tip Cell (DTC) in the C.elegans germline stem cell niche?
Through its intimate contact with germline stem cells
In the context of the stem cell niche, what is the significance of Notch-Delta Signaling?
Maintaining self-renewal and differentiation of stem cells
Which type of proteins are involved in Notch-Delta Signaling in the context of the stem cell niche?
Transmembrane proteins
Apart from promoting mitosis, what other function does the Distal Tip Cell perform within the C.elegans germline stem cell niche?
Elongating the gonadal arm during development
Test your knowledge on stem cell niches and their critical role in stem cell maintenance, self-renewal, and differentiation. Explore the complex microenvironment of niches including supporting cells, extracellular matrix components, tissue biomechanics, and secreted factors.
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