38 Questions
What virulence factors does aureus have to protect itself from neutrophil-mediated killing?
Toxin production in food
Which type of organisms are Staphylococci?
Spherical
What distinguishes Staphylococcal Food Poisoning from other foodborne illnesses regarding food taste and storage?
Has no effect on food taste
What is a major problem organism among Staphylococci according to the text?
Staphylococcus aureus
What is the primary action of Staphylococcal enterotoxins on the body?
Central Nervous System (CNS) effects
Why is antibiotic treatment deemed unnecessary for Staphylococcal Food Poisoning?
Rapid recovery without antibiotics
Which enzyme is hydrolyzed by Staphylococcus aureus according to the text?
Coagulase
Which of the following colors is associated with Staphylococcus aureus?
Yellow
Which predisposing factor increases the risk of Staphylococcal Food Poisoning?
Immunodeficiency diseases
How does Staphylococcus aureus develop resistance to antibiotics like penicillin?
By altering cell wall structure via PBP gene modification
What is a distinguishing characteristic of Staphylococcus epidermidis compared to S.aureus?
Mannitol fermentation
Which Staphylococcus species is resistant to Novobiocin?
S.epidermidis
What distinguishes Methicillin-resistant S. aureus (MRSA) from Penicillin-resistant strains?
Production of beta-lactamase enzyme
Why is S.epidermidis less susceptible to specific antibiotics compared to S.aureus according to the text?
- Novobiocin resistance
What is the function of Coagulase, as described in the text?
Converts fibrinogen to fibrin
Which of the following best describes the role of Protein A in Staphylococcus aureus?
Inhibits antibody-mediated opsonization
What effect does Catalase have on hydrogen peroxide, according to the text?
Breaks it down to O2 and H2O
How does the Capsule or slime layer contribute to the virulence of Staphylococcus aureus?
Prevents phagocytosis
Which enzyme damages connective tissue according to the text?
Hyaluronidase
What is the primary function of the Cell wall components of Staphylococcus aureus?
Binds to exposed fibronectin in wounds
Which factor makes Staphylococcus aureus look less foreign and masks its harmfulness?
Protein A
What is the main difference between nosocomial and community-associated MRSA infections?
Nosocomial infections occur in healthcare settings, while community-associated infections occur outside of healthcare facilities.
Which of the following is NOT a risk factor for nosocomial MRSA infection?
Being a healthy person without any underlying conditions
Where did the first cases of Community-Associated MRSA (CA-MRSA) infections occur?
Detroit, Michigan among IV drug users
What are the typical manifestations of Staph or MRSA infections in the community?
Usually manifested as skin infections like pimples and boils
Who is more likely to get nosocomial MRSA infections?
Patients undergoing prolonged antimicrobial chemotherapy
Which population group was NOT mentioned as being at risk for Community-Associated MRSA?
Elderly individuals in nursing homes
What defines MRSA infection as 'community-associated'?
Infections acquired by persons not recently hospitalized or having medical procedures
Which of the following is NOT a risk factor for CA-MRSA infections?
Regular visit to the hospital
What is the primary mechanism through which MRSA becomes resistant to penicillin-derived antibiotics?
Production of PBP2a protein
Which of the following antibiotics is effective against some multi-drug resistant MRSA strains?
Linezolid
What is the role of vancomycin in treating MRSA infections?
It targets and disrupts the cell wall synthesis in MRSA
Which of the following is a risk factor for CA-MRSA infections according to the text?
Methicillin use
What makes penicillin-derived antibiotics inactive in the presence of MRSA?
Hydrolysis of the β-lactam ring by zyme β-lactamases
Why are vancomycin-resistant MRSA strains a concern in healthcare settings?
They are associated with higher mortality rates
Which alternative antibiotics are mentioned in the text for treating MRSA infections?
Oxazolidinones and streptogrammins
What is the significance of PBP2a protein in methicillin-resistant S. aureus (MRSA)?
It alters the function of penicillin-binding proteins (PBP's)
Why are permanent indwelling catheters considered a risk factor for CA-MRSA infections?
They provide a direct passage for MRSA to enter the body
Learn about Staphylococcal Food Poisoning, caused by toxins produced by S. aureus in food. Understand its symptoms, rapid recovery, and how the bacteria can survive in various conditions.
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