Lecture 7
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Questions and Answers

Why is controlled oxidation preferred over simple burning in a cell?

  • It allows for the gradual release of energy that can be captured in a usable form. (correct)
  • It results in the rapid release of energy which is lost as heat.
  • It involves more complex reactions that are harder to achieve.
  • It produces a larger amount of waste products.

What occurs during the breakdown of simple subunits into Acetyl CoA, ATP, and NADH?

  • Oxidation of Acetyl CoA and substantial ATP production (correct)
  • Digestion into small, absorbable molecules
  • The conversion of glucose into pyruvate
  • Formation of larger molecules from smaller ones

What is the net result of glycolysis?

  • Formation of Acetyl CoA
  • Production of waste products
  • Conversion of glucose into pyruvate, ATP, and NADH (correct)
  • Absorption of small molecules

Where does glycolysis occur in the cell?

<p>Cytoplasm (D)</p> Signup and view all the answers

What are the 3 stages of glycolysis?

<p>Energy Investment Phase, Cleavage Phase, Energy Liberation Phase (B)</p> Signup and view all the answers

What is the role of the Energy Investment Phase in glycolysis?

<p>Requires ATP to start the process (A)</p> Signup and view all the answers

Which phase of glycolysis involves the conversion of one molecule of glucose into two molecules of pyruvate?

<p>Cleavage Phase (A)</p> Signup and view all the answers

What happens during the Energy Liberation Phase of glycolysis?

<p>Release of energy and production of ATP and NADH (C)</p> Signup and view all the answers

What is the end product of alcohol fermentation?

<p>Ethanol (A)</p> Signup and view all the answers

What is the primary function of a dehydrogenase enzyme?

<p>Removes hydrogen ions and electrons. (D)</p> Signup and view all the answers

How many ATP (net) are produced in lactic acid fermentation from one glucose molecule?

<p>2 ATP (C)</p> Signup and view all the answers

What happens to the products of glycolysis in the presence of oxygen?

<p>Undergo oxidative phosphorylation (B)</p> Signup and view all the answers

Which enzyme adds a phosphate group to a molecule?

<p>Kinase (C)</p> Signup and view all the answers

What is the role of NADH in cellular respiration?

<p>Produces ATP (A)</p> Signup and view all the answers

How do the end products differ between alcohol fermentation and lactic acid fermentation?

<p><strong>End product is ethanol</strong> in alcohol fermentation and <strong>lactic acid in lactic acid fermentation</strong>. (B)</p> Signup and view all the answers

Substrate level phosphorylation involves which process?

<p><strong>Transfer of a phosphate group directly to ADP</strong> from a substrate molecule. (D)</p> Signup and view all the answers

What is the main purpose of cellular respiration?

<p>To break down organic molecules and generate energy in the form of ATP (A)</p> Signup and view all the answers

Which term refers to the gain of electrons by a molecule?

<p>Reduction (B)</p> Signup and view all the answers

What type of reaction involves both oxidation and reduction processes?

<p>Redox reaction (C)</p> Signup and view all the answers

Why does controlled oxidation benefit a cell more than simple burning of a molecule?

<p>Controlled oxidation prevents damage to the cell through uncontrolled reactions (B)</p> Signup and view all the answers

What is the main difference between catabolism and anabolism?

<p>Catabolism releases energy, while anabolism requires energy input (D)</p> Signup and view all the answers

During which process does a molecule experience a decrease in its oxidation state?

<p>Reduction (B)</p> Signup and view all the answers

In a redox reaction, what often comes along with an electron when it is picked up?

<p>(H+) Proton (Hydrogen Ion) (B)</p> Signup and view all the answers

Which term describes the synthesis of complex molecules from simpler ones?

<p>Anabolism (A)</p> Signup and view all the answers

How does catabolism differ from anabolism?

<p>Catabolism releases energy, while anabolism requires energy input. (A)</p> Signup and view all the answers

During which process does a molecule experience an increase in its oxidation state?

<p>Oxidation (C)</p> Signup and view all the answers

During the Energy Investment Phase of glycolysis, ATP is required to start the process.

<p>True (A)</p> Signup and view all the answers

Substrate level phosphorylation occurs during the Cleavage Phase of glycolysis.

<p>False (B)</p> Signup and view all the answers

NADH production is a key outcome of the Energy Investment Phase in glycolysis.

<p>False (B)</p> Signup and view all the answers

The Energy Liberation Phase of glycolysis involves the conversion of glucose into pyruvate.

<p>True (A)</p> Signup and view all the answers

In glycolysis, the Cleavage Phase is where ATP is generated from ADP and Pi.

<p>False (B)</p> Signup and view all the answers

The Energy Investment Phase of glycolysis involves breaking down glucose into smaller molecules.

<p>False (B)</p> Signup and view all the answers

NADH is a high-energy molecule that carries electrons to the electron transport chain.

<p>True (A)</p> Signup and view all the answers

During the Cleavage Phase of glycolysis, a six-carbon glucose molecule is split into four three-carbon molecules.

<p>False (B)</p> Signup and view all the answers

Substrate level phosphorylation results in the direct formation of ATP from ADP and Pi.

<p>True (A)</p> Signup and view all the answers

Substrate level phosphorylation in glycolysis involves the direct transfer of a phosphate group to ADP from a substrate molecule.

<p>True (A)</p> Signup and view all the answers

NADH production in glycolysis requires NADP as a precursor.

<p>False (B)</p> Signup and view all the answers

Kinase is an enzyme that converts a molecule into its isomer.

<p>False (B)</p> Signup and view all the answers

Dehydrogenase enzyme removes hydrogen ions and electrons.

<p>True (A)</p> Signup and view all the answers

In the absence of oxygen, the products of glycolysis can undergo fermentation to generate only CO2.

<p>False (B)</p> Signup and view all the answers

Alcohol fermentation produces lactic acid as its end product.

<p>False (B)</p> Signup and view all the answers

Lactic Acid Fermentation produces more energy (ATP) per glucose molecule than Alcohol Fermentation.

<p>False (B)</p> Signup and view all the answers

During the Energy Investment Phase of glycolysis, ATP molecules are consumed to phosphorylate glucose.

<p>True (A)</p> Signup and view all the answers

The Cleavage Phase of glycolysis involves the conversion of one molecule of glucose into two molecules of pyruvate.

<p>True (A)</p> Signup and view all the answers

During the Energy Liberation Phase of glycolysis, NADH is produced.

<p>False (B)</p> Signup and view all the answers

Substrate-level phosphorylation in glycolysis involves the direct transfer of a phosphate group from a substrate to ADP, forming ATP.

<p>True (A)</p> Signup and view all the answers

The production of NADH in glycolysis occurs primarily during the Cleavage Phase.

<p>False (B)</p> Signup and view all the answers

In glycolysis, the Energy Investment Phase precedes the Cleavage Phase.

<p>True (A)</p> Signup and view all the answers

The Energy Liberation Phase of glycolysis results in the net production of ATP.

<p>True (A)</p> Signup and view all the answers

NAD+ is reduced to NADH during some steps of glycolysis.

<p>True (A)</p> Signup and view all the answers

The production of NADH in glycolysis involves the oxidation of NAD+.

<p>False (B)</p> Signup and view all the answers

Substrate-level phosphorylation in glycolysis occurs only once per glucose molecule.

<p>False (B)</p> Signup and view all the answers

During the Energy Investment Phase of glycolysis, ATP molecules are consumed to phosphorylate ______

<p>glucose</p> Signup and view all the answers

The Energy Liberation Phase of glycolysis generates ATP and ______, producing pyruvate molecules at the end

<p>NADH</p> Signup and view all the answers

Substrate level phosphorylation involves the transfer of a phosphate group directly to ADP from a ______ molecule

<p>substrate</p> Signup and view all the answers

NADH is needed in order for NADH to be produced in glycolysis. The cell uses NADH in oxidative phosphorylation to produce ______

<p>ATP</p> Signup and view all the answers

The Cleavage Phase of glycolysis splits the six-carbon glucose molecule into two ______-carbon molecules

<p>three</p> Signup and view all the answers

The Energy Investment Phase of glycolysis involves breaking down ______ into smaller molecules

<p>glucose</p> Signup and view all the answers

Substrate level phosphorylation in glycolysis involves the direct transfer of a phosphate group from a ______ to ADP, forming ATP

<p>substrate</p> Signup and view all the answers

NADH production in glycolysis requires ______ as a precursor

<p>NAD+</p> Signup and view all the answers

The Energy Investment Phase of glycolysis requires ______ to start the process.

<p>ATP</p> Signup and view all the answers

During the Energy Liberation Phase of glycolysis, the net production of ______ occurs.

<p>ATP</p> Signup and view all the answers

The Cleavage Phase of glycolysis involves the conversion of one molecule of glucose into two molecules of ______.

<p>pyruvate</p> Signup and view all the answers

NADH production is a key outcome of the Energy Investment Phase in glycolysis. NADH is a high-energy molecule that carries ______ to the electron transport chain.

<p>electrons</p> Signup and view all the answers

Substrate-level phosphorylation in glycolysis involves the direct transfer of a phosphate group to ADP from a ______ molecule.

<p>substrate</p> Signup and view all the answers

During glycolysis, the breakdown of simple subunits into Acetyl CoA, ATP, and NADH occurs in the ______.

<p>cytosol</p> Signup and view all the answers

In glycolysis, the Energy Investment Phase precedes the ______ Phase.

<p>Cleavage</p> Signup and view all the answers

The net result of glycolysis is the conversion of one molecule of glucose into two molecules of pyruvate, along with the production of ______ and NADH.

<p>ATP</p> Signup and view all the answers

During the Energy Investment Phase of glycolysis, __________ is required to start the process

<p>ATP</p> Signup and view all the answers

The Energy Liberation Phase of glycolysis results in the net production of _________

<p>ATP</p> Signup and view all the answers

The Cleavage Phase of glycolysis involves the conversion of one molecule of glucose into two molecules of _________

<p>pyruvate</p> Signup and view all the answers

NADH production in glycolysis occurs primarily during the _________ Phase

<p>Cleavage</p> Signup and view all the answers

Substrate level phosphorylation in glycolysis involves the direct transfer of a phosphate group to ADP from a _________ molecule

<p>substrate</p> Signup and view all the answers

During glycolysis, the Energy Investment Phase precedes the _________ Phase

<p>Cleavage</p> Signup and view all the answers

_________ involves the direct formation of ATP from ADP and Pi

<p>Substrate level phosphorylation</p> Signup and view all the answers

In glycolysis, the Cleavage Phase is where ATP is generated from ADP and Pi through _________

<p>phosphorylation</p> Signup and view all the answers

NADH is a high-energy molecule that carries electrons to the _________ transport chain

<p>electron</p> Signup and view all the answers

The net result of glycolysis includes the production of ATP and _________

<p>pyruvate</p> Signup and view all the answers

Which stage involves the breakdown of simple subunits into Acetyl CoA, ATP, and NADH in the cytosol?

<p>Stage 2 (C)</p> Signup and view all the answers

What is the primary function of anabolism?

<p>Build macromolecules (D)</p> Signup and view all the answers

During which stage of metabolism does controlled oxidation primarily occur?

<p>Catabolism (A)</p> Signup and view all the answers

What is the end product of lactic acid fermentation?

<p>Lactic Acid (D)</p> Signup and view all the answers

Which type of phosphorylation involves the direct transfer of a phosphate group to ADP from a substrate molecule?

<p>Substrate-level phosphorylation (C)</p> Signup and view all the answers

What does catabolism primarily involve?

<p>Breakdown of complex molecules to release energy (C)</p> Signup and view all the answers

Which process results in the production of more energy (ATP) per glucose molecule: Lactic acid fermentation or Alcohol fermentation?

<p>Lactic Acid Fermentation (A)</p> Signup and view all the answers

What is the net outcome of glycolysis in terms of ATP produced?

<p>$2$ ATP produced (A)</p> Signup and view all the answers

Where do the 3 stages of food molecule breakdown take place?

<p>Breakdown - Oxidation - Mitochondria (B)</p> Signup and view all the answers

Can all energy come from sugar alone?

<p>No, fats and proteins can also be used for energy (C)</p> Signup and view all the answers

What are the precursors to ATP and NADH?

<p>NAD+ (A)</p> Signup and view all the answers

Is NADH a reduced or oxidized molecule?

<p>Reduced (B)</p> Signup and view all the answers

What is the process of converting non-sugar precursors into glucose known as?

<p>Gluconeogenesis (B)</p> Signup and view all the answers

Where does glycolysis take place?

<p>Cytoplasm (D)</p> Signup and view all the answers

How many phases are there in glycolysis?

<p>3 (B)</p> Signup and view all the answers

What is the end product of glycolysis?

<p>$ ext{Pyruvate}$ (C)</p> Signup and view all the answers

In the absence of oxygen in cells unable to perform fermentation, which product of glycolysis would accumulate in the cytosol?

<p>Pyruvate (A)</p> Signup and view all the answers

Which step of glycolysis would be halted in mutated muscle cells unable to perform fermentation in anoxic conditions?

<p>Conversion of glucose to pyruvate (C)</p> Signup and view all the answers

What is the end product of processing pyruvate anaerobically?

<p>Lactic acid and ethanol (C)</p> Signup and view all the answers

Which process occurs when a mutated muscle cell is unable to perform fermentation in anoxic conditions?

<p>Glycolysis (C)</p> Signup and view all the answers

What is the primary difference between alcohol fermentation and lactic acid fermentation?

<p>End products produced (B)</p> Signup and view all the answers

Which molecule is a common precursor for both glycolysis and gluconeogenesis?

<p>Pyruvate (C)</p> Signup and view all the answers

What is the role of fermentation in the absence of oxygen for cells unable to perform it?

<p>Regenerate NAD+ (B)</p> Signup and view all the answers

What is the process that allows for the conversion of pyruvate to lactate, regenerating NAD from NADH, in the absence of oxygen?

<p>Fermentation (A)</p> Signup and view all the answers

In the context of muscle atrophy in rats, why did researchers observe an increase in gluconeogenesis in the liver?

<p>Increased energy demands due to muscle atrophy (C)</p> Signup and view all the answers

What is the significance of increased fructose 1,6-bisphosphatase activity in the liver of rats with hind-limb mobility restored?

<p>Decreased gluconeogenesis (A)</p> Signup and view all the answers

Which metabolic process is most likely to be upregulated when there is insufficient oxygen available for aerobic respiration?

<p>Glycolysis (B)</p> Signup and view all the answers

What happens to pyruvate in the absence of oxygen and without the ability to metabolize further?

<p>Undergoes fermentation to lactate (D)</p> Signup and view all the answers

Which of the following is a storage form of energy that can be metabolized for cellular purposes?

<p>Glycogen (D)</p> Signup and view all the answers

What results from the fermentation process converting pyruvate into ethanol?

<p>Regeneration of NAD (D)</p> Signup and view all the answers

Why is an increase in fructose 1,6-bisphosphatase activity crucial for gluconeogenesis during periods of high energy demand?

<p>To promote gluconeogenic carbon flow (B)</p> Signup and view all the answers

During which phase of glycolysis are 2 molecules of glyceraldehyde-3-phosphate (G3P) produced?

<p>Cleavage phase (A)</p> Signup and view all the answers

What is the main purpose of the energy recovery/generation phase in glycolysis?

<p>To produce ATP and pyruvate (B)</p> Signup and view all the answers

Which type of respiration pathway is known as anaerobic respiration?

<p>Glycolysis (D)</p> Signup and view all the answers

In cellular metabolism, what is the primary function of catabolism?

<p>To break down large molecules into smaller units (D)</p> Signup and view all the answers

Why do cells not directly burn sugar for energy?

<p>Direct burning is too slow to produce ATP efficiently (C)</p> Signup and view all the answers

What is the significance of stepwise oxidation in cellular respiration?

<p>To prevent the buildup of toxic intermediates (B)</p> Signup and view all the answers

What is the main difference between catabolism and anabolism in cellular metabolism?

<p>Catabolism involves breaking down, while anabolism involves building up molecules (B)</p> Signup and view all the answers
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