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Questions and Answers
The partition coefficient compares the concentration ratio of un-ionized species of a compound in two liquids.
The partition coefficient compares the concentration ratio of un-ionized species of a compound in two liquids.
True (A)
The distribution coefficient compares the concentration ratio of ionized species of a compound in two liquids.
The distribution coefficient compares the concentration ratio of ionized species of a compound in two liquids.
False (B)
A high octanol-water partition coefficient indicates a chemical substance is hydrophobic.
A high octanol-water partition coefficient indicates a chemical substance is hydrophobic.
True (A)
Partition coefficients are not useful in estimating drug distribution within the body.
Partition coefficients are not useful in estimating drug distribution within the body.
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Hydrophilic drugs are mainly distributed to lipid bilayers of cells.
Hydrophilic drugs are mainly distributed to lipid bilayers of cells.
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