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The partition coefficient compares the concentration ratio of un-ionized species of a compound in two liquids.
The partition coefficient compares the concentration ratio of un-ionized species of a compound in two liquids.
True
The distribution coefficient compares the concentration ratio of ionized species of a compound in two liquids.
The distribution coefficient compares the concentration ratio of ionized species of a compound in two liquids.
False
A high octanol-water partition coefficient indicates a chemical substance is hydrophobic.
A high octanol-water partition coefficient indicates a chemical substance is hydrophobic.
True
Partition coefficients are not useful in estimating drug distribution within the body.
Partition coefficients are not useful in estimating drug distribution within the body.
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Hydrophilic drugs are mainly distributed to lipid bilayers of cells.
Hydrophilic drugs are mainly distributed to lipid bilayers of cells.
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