Snake Venoms in Cancer Therapy

<p>The 1930s (C)</p> Signup and view all the answers

<p>They are more effective at targeting specific types of cancer cells. (B)</p> Signup and view all the answers

<p>Immunotherapy (A)</p> Signup and view all the answers

<p>Snake venom components are highly specific in their actions and target certain proteins or pathways involved in cancer. (A)</p> Signup and view all the answers

<p>It allows us to develop new drugs that target specific pathways involved in cancer. (D)</p> Signup and view all the answers

<p>The difficulty in obtaining large quantities of venom, particularly from rare snakes. (C)</p> Signup and view all the answers

<p>Identifying and characterizing proteins and peptides found in snake venom. (D)</p> Signup and view all the answers

<p>Creating new anti-cancer drugs. (B)</p> Signup and view all the answers

<p>Targeting the cytotoxins to specific cancer cells. (A)</p> Signup and view all the answers

<p>Nasopharyngeal carcinoma (B)</p> Signup and view all the answers

<p>A promising approach for developing targeted anti-cancer therapies. (D)</p> Signup and view all the answers

<p>Discovery of novel pain relievers (A)</p> Signup and view all the answers

<p>Snake venom can be a rich source of valuable therapeutic compounds. (A)</p> Signup and view all the answers

<p>L-amino acid oxidase (B)</p> Signup and view all the answers

<p>Apoptotic factor (D)</p> Signup and view all the answers

<p>Metalloproteinase (C)</p> Signup and view all the answers

<p>Isolated from snake venom (A)</p> Signup and view all the answers

<p>Tumor angiogenesis (C)</p> Signup and view all the answers

<p>Disintegrin protein (D)</p> Signup and view all the answers

<p>They belong to the metalloprotease/disintegrin family (B)</p> Signup and view all the answers

<p>Agkistrodon halys pallas venom (D)</p> Signup and view all the answers

<p>Obtustatin (A)</p> Signup and view all the answers

<p>Blocking αv β3 integrin (A)</p> Signup and view all the answers

<p>Contortrostatin (C)</p> Signup and view all the answers

<p>Adinbitor (B)</p> Signup and view all the answers

<p>Anti-angiogenesis (C)</p> Signup and view all the answers

<p>Hemorrhagic snake venom (D)</p> Signup and view all the answers

<p>It allows for the binding to integrins crucial for angiogenesis (D)</p> Signup and view all the answers

<p>Contortrostatin (B)</p> Signup and view all the answers

<p>They transport snake venoms to specific locations in the body. (A)</p> Signup and view all the answers

<p>From crude mixtures to the isolation of biologically active components. (B)</p> Signup and view all the answers

<p>Developing nanoparticle delivery systems for targeted therapies. (A)</p> Signup and view all the answers

<p>Emergence of more combinational treatment options. (B)</p> Signup and view all the answers

<p>Trigramin (B)</p> Signup and view all the answers

<p>To create targeted therapies. (C)</p> Signup and view all the answers

<p>Von Willebrand factor binding (A)</p> Signup and view all the answers

<p>Leucurogin (D)</p> Signup and view all the answers

<p>Crude mixtures of venoms were used. (A)</p> Signup and view all the answers

<p>It is still in an early stage of development. (B)</p> Signup and view all the answers

<p>Agkistrodon contortrix contortrix (A)</p> Signup and view all the answers

<p>A venom component that can be isolated and targeted. (A)</p> Signup and view all the answers

<p>Inhibiting α1β1 integrin (B)</p> Signup and view all the answers

<p>Leucurogin (A)</p> Signup and view all the answers

<p>Cloning and characterization of a novel disintegrin (D)</p> Signup and view all the answers

<p>Snake venom (A)</p> Signup and view all the answers

Complex mixtures of peptides, proteins, and other molecules secreted by snakes for predation or defense.

First angiotensin-converting enzyme inhibitor approved in 1981, derived from snake venom peptides.

Treatment methods like surgery and chemotherapy aimed at reducing cancer morbidity and mortality.

Biologically active substances in snake venoms that can affect living organisms, including humans.

The process of identifying new candidate medications based on the understanding of disease.

Strategies that combine various methods or substances for enhanced therapeutic effects.

A cancer treatment strategy that uses drugs to specifically target cancer cells.

Understanding snake venoms can aid in the development of novel anti-cancer drugs.

Proteins from snake venom that inhibit angiogenesis.

Disintegrin from Bothrops leucurus with anticancer properties.

Peptide from Agkistrodon contortrix achieving anti-angiogenic effects.

Disintegrin from Vipera lebetina with no classical RGD sequence.

Disintegrin that inhibits bFGF-induced cell proliferation.

Disintegrin that prevents endothelial cell proliferation.

Programmed cell death crucial for cellular balance.

Process of blood vessel formation that can fuel tumor growth.

The process of extracting specific components from snake venom glands.

Compounds in snake venom that can have medicinal effects.

A method to transport drugs to specific sites in the body.

Lab-made molecules that can bind to specific antigens on cells.

Substances that are toxic to cells, often used in cancer treatment.

The process of linking a drug to another molecule for improved targeting.

The ability of antibodies to recognize specific parts of antigens.

Nanoparticles are used to transport snake venoms to specific body locations.

Snake venoms are combined with monoclonal antibodies for targeted cancer therapy.

Snake venom use in cancer therapy evolved from crude mixtures to isolated active components.

Isolated elements of snake venoms that target specific molecular pathways.

The goal of current cancer therapies using snake venoms is to affect specific pathways in cells.

Using multiple treatment methods, like snake venoms combined with nanoparticles, is expected to grow.

The integration of nanoparticles with snake venoms is still in early research stages.

New combinational treatments using snake venoms are anticipated to develop.

A low molecular weight peptide inhibiting fibrinogen interaction with platelets.

A receptor complex on platelets vital for aggregation and clot formation.

The process of programmed cell death triggered by certain substances, including snake venoms.

Enzyme that induces apoptosis and can be found in snake venom.

Proteins from snake venom that promote cell death in vascular cells.

Family of enzymes that break down proteins and can induce apoptosis.

Used to isolate proteins that induce cytotoxicity in cancer cells.

Type of proteinases found in snake venom that induce apoptosis.