Smallpox and the Immune Response

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30 Questions

Which of the following is a risk factor for smallpox infection?

Working in a laboratory

How does smallpox spread?

Through airborne droplets

What happens when the Variola virus enters the body?

It causes secondary viremia

What are the complications of smallpox?

Blindness

When do the clinical manifestations of smallpox typically appear?

10-14 days after exposure

How is smallpox diagnosed?

By detection of smallpox-specific IgM antibodies

What is the main treatment for smallpox?

Supportive care

When should post-exposure prophylaxis be given to someone exposed to smallpox?

Within 24 hours of exposure

Is routine vaccination for smallpox still carried out?

No, routine vaccination has been discontinued

What are the priority goals of care for a client diagnosed with smallpox?

Prevent disease transmission and provide supportive care

Which virus causes smallpox?

Variola virus

What are the symptoms associated with smallpox?

Fever, malaise, headache, and back pain

When was smallpox successfully eradicated worldwide?

1980

Where does the differentiation of white blood cells begin?

Bone marrow

Which cells defend against intracellular viruses, fungi, and tumor cells?

T cells

What happens when a foreign antigen enters the body?

It is engulfed and digested by antigen-presenting cells

Which cells help activate B cells to produce antibodies?

T helper cells

What do antibodies do once they bind to affected cells?

Enable natural killer cells and cytotoxic T cells to recognize and destroy them

Which cells produce cytokines that recruit neutrophils, macrophages, and mast cells?

Natural killer cells

What were important risk factors for contracting smallpox before it was eradicated?

Close contact with an infected client or contaminated surfaces, infancy, older age, and immunodeficiency

Which of the following is a key characteristic of the smallpox rash?

The rash appears in different stages of development at the same time

What is the usual duration of smallpox illness?

3-4 weeks

Who can be at risk for contracting smallpox nowadays?

Healthcare workers and military personnel

How is smallpox transmitted?

Both A and B

What are the initial symptoms of smallpox?

Both A and B

How is smallpox diagnosed?

All of the above

What is the main goal of nursing care for smallpox?

Both A and B

When is a client with smallpox considered contagious?

Both A and B

What type of mask should a client with smallpox wear when being transported?

N95 mask

How can smallpox be prevented from becoming airborne in the absence of an airborne infection isolation room?

All of the above

Test your knowledge on the immune response and its role in eradicating smallpox, a contagious viral disease. Explore the physiology behind our body's defense system and learn about the success of vaccination in eliminating this deadly disease.

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