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Questions and Answers
Which medication is a CYP3A4 inhibitor that can elevate concentrations of CYP3A4 metabolized medications?
Which medication is a CYP3A4 inhibitor that can elevate concentrations of CYP3A4 metabolized medications?
- Ramelteon
- Grapefruit juice (correct)
- Mirtazapine
- Alcohol
What is the advised action if a patient asks to take two 8 mg doses of Ramelteon due to insomnia?
What is the advised action if a patient asks to take two 8 mg doses of Ramelteon due to insomnia?
- Advise the patient to take the two 8 mg doses as requested
- Advise the patient to consult their doctor before taking any additional Ramelteon
- Advise the patient to take only the 8 mg dose that was studied for efficacy and safety (correct)
- Advise the patient to take a different medication for insomnia
Which two antidepressants are commonly prescribed at low doses for insomnia?
Which two antidepressants are commonly prescribed at low doses for insomnia?
- Mirtazapine (Remeron) and trazodone (correct)
- Bupropion (Wellbutrin) and venlafaxine (Effexor)
- Citalopram (Celexa) and escitalopram (Lexapro)
- Fluoxetine (Prozac) and sertraline (Zoloft)
What is the active ingredient in Advil PM and Tylenol PM for sleep, and what are some common side effects?
What is the active ingredient in Advil PM and Tylenol PM for sleep, and what are some common side effects?
Which tricyclic antidepressant (TCA) is FDA approved for the treatment of insomnia?
Which tricyclic antidepressant (TCA) is FDA approved for the treatment of insomnia?
What is the most likely indication for a new prescription for Provigil 200 mg taken at 6 PM?
What is the most likely indication for a new prescription for Provigil 200 mg taken at 6 PM?
What is the preferred treatment for chronic insomnia?
What is the preferred treatment for chronic insomnia?
What are some non-pharmacological options to treat insomnia?
What are some non-pharmacological options to treat insomnia?
What are the usual doses of antidepressants used off-label for insomnia?
What are the usual doses of antidepressants used off-label for insomnia?
What is the potential risk with combining grapefruit juice and certain medications?
What is the potential risk with combining grapefruit juice and certain medications?