Muscle Contraction and Calcium Signaling Pathway Quiz
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Questions and Answers

Where do Ca ions bind to initiate contraction in cardiac muscle?

  • Sarcoplasmic reticulum
  • Ryanodine receptor-channels
  • Troponin (correct)
  • Voltage-gated Ca2+ channels

What is the primary function of the NCX antiporter in cardiac muscle?

  • Pumping Ca back into the sarcoplasmic reticulum
  • Initiating contraction by binding to troponin
  • Inducing Ca release through ryanodine receptor-channels
  • Exchanging Ca with Na+ (correct)

What causes the release of Ca sparks in cardiac muscle?

  • Activation of the Na+-K+-ATPase
  • Pumping Ca back into the sarcoplasmic reticulum
  • Voltage-gated Ca2+ channels opening in the T-tubule
  • Induction of Ca release through ryanodine receptor-channels (correct)

What happens during relaxation of cardiac muscle?

<p>Ca ions unbind from troponin (A)</p> Signup and view all the answers

What is the main difference between cardiac muscle action potentials and action potentials in neural and skeletal muscle cells?

<p>Cardiac action potentials have a higher permeability to ion X. (D)</p> Signup and view all the answers

What happens during the phase labeled as '3' in the myocardial contractile cell action potential?

<p>Ca2+ channels open; fast K+ channels close (A)</p> Signup and view all the answers

Why are cardiac action potentials unique compared to other cell types?

<p>They have a longer duration than action potentials in other cell types. (C)</p> Signup and view all the answers

What happens during the refractory period in cardiac muscle?

<p>Ion channels are inactivated, preventing further depolarization. (B)</p> Signup and view all the answers

What is the role of Na+ channels in the propagation of action potentials through the heart tissue?

<p>They generate local depolarization and activate adjacent Na+ channels. (C)</p> Signup and view all the answers

What is the function of Ca2+ channels during the myocardial contractile cell action potential?

<p>They close slowly while K+ channels open. (D)</p> Signup and view all the answers

Which factor is used to infuse Dilan each week to manage his hemophilia A?

<p>Factor VIII (C)</p> Signup and view all the answers

What is the primary cause of Jason's stroke?

<p>A blood clot (A)</p> Signup and view all the answers

Which of the following is NOT a factor that prolongs vasoconstriction during the vascular phase of hemostasis?

<p>Fibrinogen (D)</p> Signup and view all the answers

What factor is made by endothelial cells and platelets, and binds to both collagen and platelets during the platelet phase of hemostasis?

<p>von Willebrand factor (D)</p> Signup and view all the answers

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