Sjögren Syndrome
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Questions and Answers

What is the primary characteristic of Sjögren Syndrome?

  • Lymphocytic infiltration of salivary and lacrimal glands (correct)
  • Autoimmune destruction of pancreatic cells
  • Hypertrophy of the thyroid gland
  • Inflammation of synovial joints
  • Which of the following is a common age range for Sjögren Syndrome diagnosis?

  • 60-70 years
  • 30-40 years
  • 40-50 years (correct)
  • 20-30 years
  • What is the female-to-male ratio in Sjögren Syndrome prevalence?

  • 5:1
  • 9:1 (correct)
  • 12:1
  • 3:1
  • What is the hallmark symptom of keratoconjunctivitis sicca in Sjögren Syndrome?

    <p>Dry eyes</p> Signup and view all the answers

    Which classification of Sjögren Syndrome involves associations with other autoimmune diseases?

    <p>Secondary Sjögren Syndrome</p> Signup and view all the answers

    Which autoimmune diseases are commonly associated with secondary Sjögren Syndrome?

    <p>Rheumatoid arthritis and systemic lupus erythematosus</p> Signup and view all the answers

    What is the most commonly used diagnostic test for dry eyes in Sjögren Syndrome?

    <p>Schirmer tear test</p> Signup and view all the answers

    What histological finding is diagnostic in a salivary gland biopsy for Sjögren Syndrome?

    <p>Lymphocytic infiltration</p> Signup and view all the answers

    Which antibody is found in approximately 70% of Sjögren Syndrome patients?

    <p>Anti-Ro antibody</p> Signup and view all the answers

    Which of the following is NOT a clinical manifestation of Sjögren Syndrome?

    <p>Hyperthyroidism</p> Signup and view all the answers

    Which investigation is primarily used to evaluate renal involvement in Sjögren Syndrome?

    <p>24-hour urine collection</p> Signup and view all the answers

    What is the primary purpose of hypromellose in managing Sjögren Syndrome?

    <p>Treating keratoconjunctivitis sicca</p> Signup and view all the answers

    Which of the following is NOT a common extra-glandular manifestation of Sjögren Syndrome?

    <p>Cardiac arrhythmias</p> Signup and view all the answers

    What is the gold standard for confirming Sjögren Syndrome diagnosis?

    <p>Lip or salivary gland biopsy</p> Signup and view all the answers

    Which symptom is most commonly associated with interstitial lung disease in Sjögren Syndrome?

    <p>Chronic cough</p> Signup and view all the answers

    What is the risk of lymphoma in Sjögren Syndrome attributed to?

    <p>Lymphocytic infiltration</p> Signup and view all the answers

    What condition does the Saxon test evaluate in Sjögren Syndrome patients?

    <p>Dry eyes</p> Signup and view all the answers

    Which of the following treatments is used for vaginal dryness in Sjögren Syndrome?

    <p>Vaginal lubricants</p> Signup and view all the answers

    What percentage of Sjögren Syndrome patients typically show positive ANA serology?

    <p>70%</p> Signup and view all the answers

    Which organ system is primarily targeted in Sjögren Syndrome?

    <p>Exocrine glands</p> Signup and view all the answers

    Study Notes

    Sjögren Syndrome MCQs

    • Primary characteristic: Lymphocytic infiltration of salivary and lacrimal glands.
    • Common age range for diagnosis: 40-50 years.
    • Female-to-male prevalence ratio: 9:1.
    • Hallmark symptom of keratoconjunctivitis sicca: Dry eyes.
    • Sjögren Syndrome classification with associations to other autoimmune diseases: Secondary Sjögren Syndrome.
    • Commonly associated autoimmune diseases: Rheumatoid arthritis, and systemic lupus erythematosus; Hyperthyroidism and Graves' disease.
    • Diagnostic test for dry eyes: Schirmer tear test.
    • Diagnostic histological finding in salivary gland biopsy: Lymphocytic infiltration.
    • Antibody commonly found in patients: Anti-La antibody.
    • Not a clinical manifestation: Peripheral neuropathy.
    • Investigation for renal involvement: 24-hour urine collection.
    • Primary purpose of hypromellose: Treating dry mouth and keratoconjunctivitis sicca.
    • Not a common extra-glandular manifestation: Cardiac arrhythmias.
    • Gold standard for diagnosis: Lip or salivary gland biopsy.
    • Symptom associated with interstitial lung disease: Sudden dyspnea.
    • Cause of lymphoma risk: Chronic inflammation.
    • Condition evaluated by the Saxon test: Dry mouth.
    • Treatment for vaginal dryness: Vaginal lubricants.
    • Percentage of patients with positive ANA serology: 70%.
    • Primary target organ system: Exocrine glands.

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    Sjogren Syndrome MCQs PDF

    Description

    Test your knowledge on Sjögren Syndrome with this set of multiple choice questions. Covering characteristics, common associations, symptoms, and diagnostic tests, this quiz will enhance your understanding of this autoimmune condition. Ideal for medical students and professionals looking to reinforce their knowledge.

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