Signaling Transduction Proteins Quiz
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Questions and Answers

What is the main function of GTP-binding proteins in protein activation and inactivation signalling mechanisms?

  • Facilitate dephosphorylation of proteins
  • Catalyze phosphorylation reactions
  • Promote conformational changes in proteins
  • Regulate protein interactions by binding to GTP or GDP (correct)
  • Which of the following is NOT a main type of intracellular signalling complex?

  • Second messenger complex
  • G-Protein coupled receptor complex
  • Phosphorylation complex (correct)
  • Adaptor protein complex
  • What happens to a protein when it undergoes a conformational change in response to a biological signal?

  • It becomes inactive
  • It binds to GTP
  • It switches between active and inactive states (correct)
  • It gets phosphorylated
  • Which group of signalling interaction domains are commonly involved in protein-protein interactions that regulate cell signaling?

    <p>SH2 domains</p> Signup and view all the answers

    Among the types of signal transduction proteins, which type typically function as enzymes that catalyze phosphorylation reactions?

    <p>Kinases</p> Signup and view all the answers

    What determines the duration of a protein's active state in an intracellular signalling pathway?

    <p>Dephosphorylation</p> Signup and view all the answers

    What defines the signalling function of signal transduction proteins?

    <p>Presence of catalytic activity</p> Signup and view all the answers

    Which type of signal transduction proteins possess intrinsic enzyme activity?

    <p>Enzymes</p> Signup and view all the answers

    What distinguishes adaptor proteins from enzymes in signal transduction?

    <p>Intrinsic enzyme activity</p> Signup and view all the answers

    Which type of proteins contain unique DNA-binding domains among signal transduction proteins?

    <p>Gene regulatory proteins</p> Signup and view all the answers

    What type of domain do gene regulatory proteins contain that is distinctive among signal transduction proteins?

    <p>DNA-binding domain</p> Signup and view all the answers

    Which type of signal transduction protein possesses modular signalling domains but lacks intrinsic enzyme activity?

    <p>Adaptor proteins</p> Signup and view all the answers

    What is the main function of protein kinases in intracellular signalling pathways?

    <p>Add phosphate group to activate intracellular signalling protein</p> Signup and view all the answers

    Which type of proteins relay messages from G-protein coupled receptors?

    <p>Large trimeric GTP-binding proteins</p> Signup and view all the answers

    What is the main function of protein phosphatases in cell signalling?

    <p>Remove phosphate group to deactivate intracellular signalling protein</p> Signup and view all the answers

    Which mechanism can shut off intracellular signalling proteins by hydrolysing bound GTP to GDP?

    <p>GTPase cycle</p> Signup and view all the answers

    Which type of proteins are often organized into phosphorylation cascades in cell signalling pathways?

    <p>Serine/Threonine Kinases</p> Signup and view all the answers

    What are the two main types of interactions involved in the transduction of signals in intracellular signalling complexes?

    <p>Protein-2nd Messengers, Protein-Protein</p> Signup and view all the answers

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