Podcast
Questions and Answers
What is the main function of GTP-binding proteins in protein activation and inactivation signalling mechanisms?
What is the main function of GTP-binding proteins in protein activation and inactivation signalling mechanisms?
- Facilitate dephosphorylation of proteins
- Catalyze phosphorylation reactions
- Promote conformational changes in proteins
- Regulate protein interactions by binding to GTP or GDP (correct)
Which of the following is NOT a main type of intracellular signalling complex?
Which of the following is NOT a main type of intracellular signalling complex?
- Second messenger complex
- G-Protein coupled receptor complex
- Phosphorylation complex (correct)
- Adaptor protein complex
What happens to a protein when it undergoes a conformational change in response to a biological signal?
What happens to a protein when it undergoes a conformational change in response to a biological signal?
- It becomes inactive
- It binds to GTP
- It switches between active and inactive states (correct)
- It gets phosphorylated
Which group of signalling interaction domains are commonly involved in protein-protein interactions that regulate cell signaling?
Which group of signalling interaction domains are commonly involved in protein-protein interactions that regulate cell signaling?
Among the types of signal transduction proteins, which type typically function as enzymes that catalyze phosphorylation reactions?
Among the types of signal transduction proteins, which type typically function as enzymes that catalyze phosphorylation reactions?
What determines the duration of a protein's active state in an intracellular signalling pathway?
What determines the duration of a protein's active state in an intracellular signalling pathway?
What defines the signalling function of signal transduction proteins?
What defines the signalling function of signal transduction proteins?
Which type of signal transduction proteins possess intrinsic enzyme activity?
Which type of signal transduction proteins possess intrinsic enzyme activity?
What distinguishes adaptor proteins from enzymes in signal transduction?
What distinguishes adaptor proteins from enzymes in signal transduction?
Which type of proteins contain unique DNA-binding domains among signal transduction proteins?
Which type of proteins contain unique DNA-binding domains among signal transduction proteins?
What type of domain do gene regulatory proteins contain that is distinctive among signal transduction proteins?
What type of domain do gene regulatory proteins contain that is distinctive among signal transduction proteins?
Which type of signal transduction protein possesses modular signalling domains but lacks intrinsic enzyme activity?
Which type of signal transduction protein possesses modular signalling domains but lacks intrinsic enzyme activity?
What is the main function of protein kinases in intracellular signalling pathways?
What is the main function of protein kinases in intracellular signalling pathways?
Which type of proteins relay messages from G-protein coupled receptors?
Which type of proteins relay messages from G-protein coupled receptors?
What is the main function of protein phosphatases in cell signalling?
What is the main function of protein phosphatases in cell signalling?
Which mechanism can shut off intracellular signalling proteins by hydrolysing bound GTP to GDP?
Which mechanism can shut off intracellular signalling proteins by hydrolysing bound GTP to GDP?
Which type of proteins are often organized into phosphorylation cascades in cell signalling pathways?
Which type of proteins are often organized into phosphorylation cascades in cell signalling pathways?
What are the two main types of interactions involved in the transduction of signals in intracellular signalling complexes?
What are the two main types of interactions involved in the transduction of signals in intracellular signalling complexes?
