Cell Communication 1
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Questions and Answers

What property of signal transduction is achieved by precise molecular complementarity between signal and receptor molecules?

  • Sensitivity
  • Amplification
  • Specificity (correct)
  • Cooperativity

Which property of signal transduction is characterized by small changes in ligand concentration causing large changes in receptor activation?

  • Amplification
  • Sensitivity
  • Specificity
  • Cooperativity (correct)

What property of signal transduction involves the activation of many molecules of a second enzyme by an initially activated enzyme?

  • Amplification (correct)
  • Cooperativity
  • Sensitivity
  • Specificity

In signal transduction, what is the result of a nerve cell being either stimulated to transmit a full impulse or remaining in its resting state?

<p>Activation of multiple receptors (D)</p> Signup and view all the answers

What characteristic makes signal transductions highly specific and extremely sensitive?

<p>Molecular complementarity between signals and receptors (D)</p> Signup and view all the answers

What type of signal is produced by the target cell, secreted, and affects the target cell itself via receptors?

<p>Autocrine (B)</p> Signup and view all the answers

In which type of signaling do signals target distant cells via hormones released into the bloodstream?

<p>Endocrine (D)</p> Signup and view all the answers

Which type of receptor receives chemical signals from both outside and inside the cell?

<p>Intracrine receptor (D)</p> Signup and view all the answers

What do effector proteins do in response to signaling molecules?

<p>Elicit cellular responses (B)</p> Signup and view all the answers

Which term describes the phenomenon where different cell types may have different sets of receptors for the same ligand, each inducing a different response?

<p>Receptor specificity (A)</p> Signup and view all the answers

"Cholinergic receptors" respond to which ligand?

<p>Acetylcholine (A)</p> Signup and view all the answers

What is the role of desensitization in cell signaling?

<p>Cells adjust their sensitivity to a signal (A)</p> Signup and view all the answers

How does affinity play a role in cell signaling?

<p>It allows the receptor to detect high concentrations of signal molecules (C)</p> Signup and view all the answers

What is the purpose of integration in cell signaling?

<p>To produce a unified response to multiple signals (D)</p> Signup and view all the answers

Which of the following is NOT a type of signal to which cells respond?

<p>Intracellular lipids (C)</p> Signup and view all the answers

What is one effect of continuous presence of a signal on receptors?

<p>Desensitization (C)</p> Signup and view all the answers

How does cell type specificity contribute to signal response?

<p>Helps cells respond to specific combinations of signals (D)</p> Signup and view all the answers

What is the main characteristic of a metabotropic receptor?

<p>Acts through a second messenger system (B)</p> Signup and view all the answers

Which type of receptors increase sodium permeability across the membrane?

<p>Excitatory ionotropic receptors (C)</p> Signup and view all the answers

Which type of receptor is an example of an enzyme-linked receptor?

<p>Receptor Tyrosine Kinase (RTK) (A)</p> Signup and view all the answers

What is the function of ligand-gated ion channels?

<p>Forms ion channel pores (A)</p> Signup and view all the answers

Which type of receptor depends on equilibrium potential to produce excitatory or inhibitory effects?

<p>Ionotropic receptors (A)</p> Signup and view all the answers

What is the main function of G-protein coupled receptors (GPCRs)?

<p>Acts through a second messenger system (A)</p> Signup and view all the answers

What is the main function of ligands in cellular signaling?

<p>Bind to a receptor to produce a signal (C)</p> Signup and view all the answers

Which of the following correctly describes agonists in cellular signaling?

<p>Mimic the effects of natural ligands by binding to a receptor (C)</p> Signup and view all the answers

What do antagonists do in cellular signaling?

<p>Block the effects of agonists by binding to receptors (D)</p> Signup and view all the answers

Which type of molecules can act as first messengers in extracellular signaling?

<p>Steroids (D)</p> Signup and view all the answers

What do neurotransmitters primarily transmit signals between?

<p>Neurons (D)</p> Signup and view all the answers

Which of the following is classified as an amine neurotransmitter?

<p>A and C (D)</p> Signup and view all the answers

What distinguishes an agonist from an antagonist in cellular signaling?

<p>Agonists mimic natural ligands, antagonists block their effects (A)</p> Signup and view all the answers

Catecholamines like dopamine and norepinephrine serve as neurotransmitters. What is their classification based on?

<p>Structure (A)</p> Signup and view all the answers

Amino acids, such as GABA and glutamate, function as neurotransmitters. What sets them apart from other neurotransmitter types?

<p>Transmission across synapses (D)</p> Signup and view all the answers

What type of response can be triggered by a signaling pathway where there is a gradually increasing concentration of an extracellular signal?

<p>Complete and full intensity response (A)</p> Signup and view all the answers

How does a negative feedback loop in cellular signaling operate?

<p>Suppresses its own production (D)</p> Signup and view all the answers

Which factor influences the speed of a cellular response to extracellular signals?

<p>Turnover of signaling molecules (B)</p> Signup and view all the answers

What role do effector proteins play in response to signaling molecules?

<p>Amplify the signal (A)</p> Signup and view all the answers

How do target cells adjust their responses to extracellular signals?

<p>Using different mechanisms (A)</p> Signup and view all the answers

What characterizes a cellular response in an all-or-none mechanism based on the strength of the stimulus?

<p>Complete and full intensity or totally absent (D)</p> Signup and view all the answers

How is specificity achieved in signal transductions?

<p>By precise molecular complementarity between signal and receptor molecules (A)</p> Signup and view all the answers

What property of signal transduction involves small changes in ligand concentration causing large changes in receptor activation?

<p>Cooperativity (D)</p> Signup and view all the answers

What happens when an enzyme once activated catalyzes the activation of many molecules of a second enzyme?

<p>Amplification (B)</p> Signup and view all the answers

In signal transductions, what distinguishes a full nervous impulse from a nerve cell's resting state?

<p>Ligand concentration (B)</p> Signup and view all the answers

What is a key feature of signal transductions that leads to high sensitivity?

<p>Small changes in ligand concentration (A)</p> Signup and view all the answers

Which type of signaling involves signals produced by the target cell, secreted, and affecting the target cell itself via receptors?

<p>Autocrine (B)</p> Signup and view all the answers

What type of receptors respond to ligands like Acetylcholine?

<p>Cholinergic receptors (B)</p> Signup and view all the answers

In cellular signaling, what role do effector proteins play in response to signaling molecules?

<p>Elicit cellular responses to signaling molecules (C)</p> Signup and view all the answers

What is the main function of G-protein coupled receptors (GPCRs) in signaling pathways?

<p>Act as first messengers in extracellular signaling (A)</p> Signup and view all the answers

Which type of receptors increase sodium permeability across the membrane?

<p>Ligand-gated ion channels (A)</p> Signup and view all the answers

What distinguishes ligands from receptors in terms of binding specificity?

<p>Receptors exhibit high binding versatility while ligands display high specificity (A)</p> Signup and view all the answers

What is the main function of ligands in cellular signaling?

<p>Change the properties of the receptor (C)</p> Signup and view all the answers

Which neurotransmitter transmits signals across a synapse?

<p>Acetylcholine (A)</p> Signup and view all the answers

What sets amine neurotransmitters apart from other types of neurotransmitters?

<p>They have distinct classifications such as catecholamines (C)</p> Signup and view all the answers

Which class of molecules can act as first messengers in extracellular signaling?

<p>Nucleotides (A)</p> Signup and view all the answers

What is the role of agonists in cellular signaling?

<p>Mimic the effects of natural ligands by binding to receptors (A)</p> Signup and view all the answers

Which type of signal is produced by the target cell and affects itself via receptors?

<p>Autocrine signal (A)</p> Signup and view all the answers

What is a common characteristic of neurotransmitters like endorphins and endogenous opioids?

<p>They are peptides (A)</p> Signup and view all the answers

What do antagonists do in cellular signaling?

<p>Block the effects of agonists by binding to receptors (D)</p> Signup and view all the answers

What distinguishes GABA and glutamate among neurotransmitter types?

<p>They are amino acids (D)</p> Signup and view all the answers

Which term describes the phenomenon where different cell types may have different sets of receptors for the same ligand, each inducing a different response?

<p>Functional selectivity (D)</p> Signup and view all the answers

What type of receptor forms ion channel pores upon ligand binding?

<p>Ionotropic receptor (A)</p> Signup and view all the answers

Which type of receptor initiates metabolic steps through a second messenger system?

<p>G-protein coupled receptor (B)</p> Signup and view all the answers

What is the main function of Receptor Tyrosine Kinases (RTKs) among the major types of cell surface receptors?

<p>Phosphorylating tyrosine residues (D)</p> Signup and view all the answers

What effect results from inhibitory ionotropic receptors increasing chloride permeability across the membrane?

<p>Increased hyperpolarization (D)</p> Signup and view all the answers

Which type of receptor responds to ligands by activating G-proteins and initiating downstream signaling pathways?

<p>Metabotropic receptor (B)</p> Signup and view all the answers

What distinguishes enzyme-linked receptors like Guanylyl Cyclases among cell surface receptors?

<p>Phosphorylating tyrosine residues (D)</p> Signup and view all the answers

What is the main difference between autocrine and paracrine signaling?

<p>Autocrine signals are produced by the target cell, while paracrine signals are produced by the emitting cell (A)</p> Signup and view all the answers

What is the function of effector proteins in cellular responses to signaling molecules?

<p>Elicit cellular responses (C)</p> Signup and view all the answers

Which type of receptor displays high ligand binding specificity to different types of ligands?

<p>Polyvalent receptors (D)</p> Signup and view all the answers

What happens when the same ligand binds to different receptors on various cell types?

<p>It induces different responses in each type of cell (D)</p> Signup and view all the answers

What is the main function of second messengers in cellular signaling pathways?

<p>Amplifying the signal by triggering a cascade of biochemical reactions (C)</p> Signup and view all the answers

Which type of receptor directly opens ion channels upon binding with a ligand?

<p>Ligand-gated ion channel receptor (B)</p> Signup and view all the answers

How do molecular switches affect proteins/enzymes in cellular signaling?

<p>Regulate the activity or function of proteins/enzymes (D)</p> Signup and view all the answers

What distinguishes intracellular signaling pathways from extracellular signaling pathways?

<p>The requirement for signal transduction in intracellular signaling (D)</p> Signup and view all the answers

Which cellular process involves converting an external signal into a chemical change within the cell?

<p>Signal transduction (B)</p> Signup and view all the answers

What is a key feature of universal properties of living cells related to intracellular signaling proteins?

<p>They are shared among different cell types (C)</p> Signup and view all the answers

What is the main function of desensitization in cell signaling?

<p>Decrease sensitivity to a continuous signal (A)</p> Signup and view all the answers

How does desensitization impact the cell's response to continuous signaling?

<p>Decreases cellular sensitivity (B)</p> Signup and view all the answers

What does integration refer to in cell signaling?

<p>Unifying multiple signals for a single response (C)</p> Signup and view all the answers

Which mechanism allows cells to respond to changes in extracellular signal molecule concentration?

<p>Specific receptor sets (C)</p> Signup and view all the answers

How can desensitization be reversed in cells?

<p>By reactivating receptors when stimulus falls below threshold (B)</p> Signup and view all the answers

What characteristic enables cells to detect picomolar concentrations of signal molecules?

<p>Receptor affinity (C)</p> Signup and view all the answers

What role do second messengers play in cell signaling?

<p>Generate signaling molecules in response to receptor activation (B)</p> Signup and view all the answers

Which of the following is a function of DIACYLGLYCEROL (DAG) as a second messenger?

<p>Regulates membrane-associated effector proteins (D)</p> Signup and view all the answers

What is the role of INOSITOL 1,4,5-TRISPHOSPHATE (IP3) as a second messenger?

<p>Activates transmembrane receptors (A)</p> Signup and view all the answers

Which type of receptor facilitates cell-extracellular matrix adhesion?

<p>Integrins (C)</p> Signup and view all the answers

What distinguishes CYCLIC ADENOSINE MONOPHOSPHATE (cAMP) among second messengers?

<p>Diffusion to other parts of the cell (C)</p> Signup and view all the answers

What is the main function of the ionotropic receptor?

<p>Forming ion channel pores upon ligand binding (C)</p> Signup and view all the answers

Which type of receptor among the major cell surface receptors is an example of an enzyme-linked receptor?

<p>Receptor Tyrosine Kinase (RTK) (B)</p> Signup and view all the answers

What distinguishes ligand-gated ion channels among the major types of cell surface receptors?

<p>Forming ion channels upon ligand binding (D)</p> Signup and view all the answers

What is the primary role of Guanylyl Cyclases among the enzyme-linked receptors?

<p>Catalyzing the formation of cyclic GMP from GTP (D)</p> Signup and view all the answers

In cellular signaling, what effect does an inhibitory ionotropic receptor have by increasing chloride permeability across the membrane?

<p>Increases cell inhibition (D)</p> Signup and view all the answers

'Toll-like receptors' are an example of which type of major cell surface receptor?

<p>Enzyme-linked (coupled) receptors (A)</p> Signup and view all the answers

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