16 Questions
What is another name for the shunt pathway according to the text?
Pentose monophosphate pathway
Where does the HMP shunt pathway occur within the cell?
Cytosol
How many molecules of glucose-6-phosphate enter the pentose phosphate pathway cycle?
Three
Which hydrogen acceptor is involved in the HMP pathway according to the text?
NADP
What is produced in the EM pathway instead of CO2?
ATP
Which stage of the Pentose Phosphate Pathway involves irreversible oxidative reactions?
Stage 1 oxidative reactions
What is the primary function of the pentose phosphate pathway in erythrocytes?
Generation of NADPH to maintain reduced glutathione
Which of the following organs does not require the oxidative reactions of the pentose phosphate pathway?
Skeletal muscle
What is the primary function of the non-oxidative reactions of the pentose phosphate pathway?
Synthesis of nucleotides and nucleic acids
What is the primary consequence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in erythrocytes?
Decreased ability to detoxify free radicals
Which of the following is a precipitating factor for hemolytic anemia in individuals with G6PD deficiency?
Ingestion of fava beans
What is the primary function of NADPH generated by the pentose phosphate pathway in macrophages?
Generation of superoxide anion radicals to kill bacteria
Which of the following is a characteristic of hemolytic anemia caused by G6PD deficiency?
Jaundice
What is the primary function of NADPH generated by the pentose phosphate pathway in the lens of the eye?
Maintenance of lens protein transparency
What is the primary function of NADPH generated by the pentose phosphate pathway in testes and ovaries?
Synthesis of steroid hormones
What is the primary function of NADPH generated by the pentose phosphate pathway in lactating mammary glands?
Synthesis of fatty acids for milk production
Test your knowledge on the shunt pathway, also known as the pentose phosphate pathway or hexose monophosphate shunt. Learn about this alternative pathway for glucose oxidation, where about 10% of glucose per day enters. Explore how three molecules of glucose-6-phosphate result in the production of CO2 and 5 carbon residues.
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