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16 Questions

What is another name for the shunt pathway according to the text?

Pentose monophosphate pathway

Where does the HMP shunt pathway occur within the cell?

Cytosol

How many molecules of glucose-6-phosphate enter the pentose phosphate pathway cycle?

Three

Which hydrogen acceptor is involved in the HMP pathway according to the text?

NADP

What is produced in the EM pathway instead of CO2?

ATP

Which stage of the Pentose Phosphate Pathway involves irreversible oxidative reactions?

Stage 1 oxidative reactions

What is the primary function of the pentose phosphate pathway in erythrocytes?

Generation of NADPH to maintain reduced glutathione

Which of the following organs does not require the oxidative reactions of the pentose phosphate pathway?

Skeletal muscle

What is the primary function of the non-oxidative reactions of the pentose phosphate pathway?

Synthesis of nucleotides and nucleic acids

What is the primary consequence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in erythrocytes?

Decreased ability to detoxify free radicals

Which of the following is a precipitating factor for hemolytic anemia in individuals with G6PD deficiency?

Ingestion of fava beans

What is the primary function of NADPH generated by the pentose phosphate pathway in macrophages?

Generation of superoxide anion radicals to kill bacteria

Which of the following is a characteristic of hemolytic anemia caused by G6PD deficiency?

Jaundice

What is the primary function of NADPH generated by the pentose phosphate pathway in the lens of the eye?

Maintenance of lens protein transparency

What is the primary function of NADPH generated by the pentose phosphate pathway in testes and ovaries?

Synthesis of steroid hormones

What is the primary function of NADPH generated by the pentose phosphate pathway in lactating mammary glands?

Synthesis of fatty acids for milk production

Test your knowledge on the shunt pathway, also known as the pentose phosphate pathway or hexose monophosphate shunt. Learn about this alternative pathway for glucose oxidation, where about 10% of glucose per day enters. Explore how three molecules of glucose-6-phosphate result in the production of CO2 and 5 carbon residues.

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