5 Questions
In RBCs, what is the role of NADPH in connection to reduced glutathione?
Protects against oxidative damage
What is the main product of the oxidative phase of the HMP shunt pathway?
NADPH
What can result from glucose 6 phosphate dehydrogenase deficiency in RBCs?
Increased susceptibility to oxidative damage
What is the significance of NADPH in the respiratory burst mechanism of WBCs?
Facilitates destruction of pathogens
What is the main function of the HMP shunt pathway in relation to fatty acids and cholesterol?
Provides reducing equivalents for biosynthesis
Study Notes
NADPH in RBCs
- NADPH is essential for maintaining reduced glutathione, which protects RBCs from oxidative damage
HMP Shunt Pathway
- The main product of the oxidative phase of the HMP shunt pathway is NADPH
Glucose 6 Phosphate Dehydrogenase Deficiency
- Deficiency in glucose 6 phosphate dehydrogenase in RBCs can lead to hemolytic anemia
NADPH in WBCs
- NADPH is necessary for the respiratory burst mechanism in WBCs, which is crucial for killing engulfed microorganisms
HMP Shunt Pathway and Lipids
- The HMP shunt pathway is involved in the synthesis of fatty acids and cholesterol
Test your knowledge of the HMP shunt pathway with questions about its site and subcellular location, oxidative phase reactions, significance of NADPH, and its role in RBCs and WBCs.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
