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Questions and Answers
What causes shingles in individuals with a history of chickenpox?
What causes shingles in individuals with a history of chickenpox?
- Reactivation of the varicella-zoster virus (correct)
- Initial infection with the varicella-zoster virus
- Reinfection with chickenpox
- Reactivation of the herpes simplex virus
Where does the dormant varicella-zoster virus reside in the body?
Where does the dormant varicella-zoster virus reside in the body?
- In the lymph nodes
- In the dorsal nerve root ganglia (correct)
- In the bloodstream
- In the muscle tissues
Which method is NOT used for diagnosing shingles?
Which method is NOT used for diagnosing shingles?
- Tzanck smear
- Blood culture (correct)
- Visual examination
- Viral culture
Who is at risk of contracting herpes zoster?
Who is at risk of contracting herpes zoster?
What is a common symptom that may persist after herpes zoster lesions resolve?
What is a common symptom that may persist after herpes zoster lesions resolve?
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Study Notes
Shingles Overview
- Shingles results from the reactivation of the varicella-zoster virus in individuals with a history of chickenpox.
- Occurs during immunocompromised states, indicating a link between immune health and the likelihood of developing shingles.
Virus Dormancy
- The varicella-zoster virus remains dormant in the dorsal nerve root ganglia of sensory cranial and spinal nerves after initial chickenpox infection.
Symptoms and Presentation
- Herpes zoster manifests as painful eruptions in a segmental distribution along the skin area corresponding to the infected nerve, typically appearing after days of discomfort.
Diagnosis
- Diagnosis involves visual examination, Tzanck smear to confirm herpes infection, and viral culture to identify the specific virus involved.
Postherpetic Neuralgia
- After lesions heal, patients may continue to experience postherpetic neuralgia, characterized by severe pain in the affected area.
Contagion
- Shingles is contagious to those who have never had chickenpox or have not been vaccinated, highlighting the importance of vaccination in preventing outbreaks.
Related Viruses
- Herpes simplex virus (HSV) includes type 1, mainly causing cold sores (usually on the lip), and type 2, linked to genital herpes, typically below the waist; both types are contagious and can co-occur.
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