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Questions and Answers
Which of the following organisms employ the shikimate pathway?
What is the origin of the name 'shikimic acid'?
What are the precursors of a wide range of alkaloid structures?
What is the role of phosphoenolpyruvate and D-erythrose 4-phosphate in the shikimate pathway?
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What is the common feature of cinnamic acids, coumarins, lignans, and flavonoids?
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What is the source of L-phenylalanine, L-tyrosine, and L-tryptophan for animals?
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What is the role of shikimic acid in the shikimate pathway?
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What is the relationship between phenylalanine, tyrosine, and tryptophan?
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What is the common feature of the compounds formed from phenylalanine and tyrosine?
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Why are microorganisms and plants capable of synthesizing L-phenylalanine, L-tyrosine, and L-tryptophan?
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Study Notes
The Shikimate Pathway
- Provides three essential amino acids: L-phenylalanine, L-tyrosine, and L-tryptophan
- Employed by microorganisms and plants, but not by animals, making these amino acids essential dietary components
- Central intermediate in the pathway is shikimic acid, which was first isolated from Illicium species (Japanese 'shikimi') plants
- Phosphoenolpyruvate and D-erythrose 4-phosphate combine to form the aromatic amino acids phenylalanine and tyrosine
Aromatic Amino Acids and Derivatives
- Phenylalanine and tyrosine form the basis of C6C3 phenylpropane units, such as:
- Cinnamic acids
- Coumarins
- Lignans
- Flavonoids
- Along with tryptophan, these amino acids are precursors to a wide range of alkaloid structures
The Shikimate Pathway
- Provides three essential amino acids: L-phenylalanine, L-tyrosine, and L-tryptophan
- Employed by microorganisms and plants, but not by animals, making these amino acids essential dietary components
- Central intermediate in the pathway is shikimic acid, which was first isolated from Illicium species (Japanese 'shikimi') plants
- Phosphoenolpyruvate and D-erythrose 4-phosphate combine to form the aromatic amino acids phenylalanine and tyrosine
Aromatic Amino Acids and Derivatives
- Phenylalanine and tyrosine form the basis of C6C3 phenylpropane units, such as:
- Cinnamic acids
- Coumarins
- Lignans
- Flavonoids
- Along with tryptophan, these amino acids are precursors to a wide range of alkaloid structures
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Description
This quiz covers the shikimate pathway, which is employed by microorganisms and plants to produce essential amino acids like L-phenylalanine, L-tyrosine, and L-tryptophan. Learn about the role of shikimic acid and other intermediates in this pathway.
