Ischemia and Cardiopulmonary Bypass (CPB) Complications

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Questions and Answers

What is the main complication in patients with acute coronary syndromes?

  • Clinical hypertension
  • Clinical hypotension
  • Clinical ischemia (correct)
  • Clinical arrhythmia

What can be extremely difficult to determine in patients referred for bypass surgery?

  • The severity of the syndrome
  • The duration of the syndrome
  • The severity and duration of the syndrome (correct)
  • The amount of collateral flow

What is the result of reperfusion and reoxygenation injury?

  • A decrease in the severity of the syndrome (correct)
  • An increase in the duration of the syndrome
  • A decrease in the severity and duration of the syndrome
  • An increase in the amount of collateral flow

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Study Notes

  • Clinical ischemia before cardiopulmonary bypass (CPB) is a common complication in patients with acute coronary syndromes.
  • In most cases, ischemia is active in both the distribution of the principally involved artery (cardiologists call this the “infarct artery”) but also distributions in which preexistent collateral flow may be compromised.
  • Patients referred for bypass surgery in these circumstances almost always have multi-vessel disease patterns making the myocardial substrate dangerous from the standpoint of the severity and duration of the syndrome, which can be extremely difficult if not impossible to determine.
  • Reperfusion and reoxygenation injury occur when these conditions change abruptly before effective measures are implemented.

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